Results 31 to 40 of about 672,834 (294)

The Role of Ketamine in the Treatment of Bipolar Depression: A Scoping Review

Brain Sciences, 2023
Bipolar depression remains a clinical challenge with a quarter of patients failing to respond to initial conventional treatments. Although ketamine has been extensively studied in unipolar depression, its role in bipolar disorder remains inconclusive ...
Muhammad Youshay Jawad, Saleha Qasim, Menglu Ni, Ziji Guo, Joshua D. Di Vincenzo, Giacomo d’Andrea, Aniqa Tabassum, Andrea Mckenzie, Sebastian Badulescu, Iria Grande, Roger S. McIntyre   +10 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Accelerated transcranial magnetic stimulation (aTMS) to treat depression with treatment switching: study protocol of a pilot, randomized, delayed-start trial

Pilot and Feasibility Studies, 2021
Background Repetitive transcranial magnetic stimulation (rTMS) is a technique for stimulating brain activity using a transient magnetic field to induce an electrical current in the brain producing depolarization of focal groups of brain cells.
Xiao Wei Tan, Edimansyah Abdin, Phern Chern Tor   +2 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Development and initial validation of the Music Mood-Regulation Scale. [PDF]

, 2008
This is an open access journalThis study designed a measure to assess the perceived effectiveness of music as a strategy to regulate mood among a sport and exercise population.
Karag, Costas I., Hewston, Ruth M., Lane, Andrew M.   +2 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Institutional Compassion in Student Transition to University: Findings from the Nurture-U Compassionate Campus Project

Education Sciences
Compassionate university practices can increase students’ sense of belonging and lead to higher wellbeing. This study presents qualitative data from a UK university collected as part of the Nurture-U Compassionate Campus project.
Jemima Dooley, Vanessa Forbes, Amelia Green, Pranati Misurya, Polly Card, Felicity Thomas, Ed Watkins, Louise Lawrence   +7 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Cognitive and mood effects in healthy children during 12 weeks' supplementation with multi-vitamin/minerals [PDF]

, 2008
Adequate levels of vitamins and minerals are essential for optimal neural functioning. A high proportion of individuals, including children, suffer from deficiencies in one or more vitamins or minerals.
Kennedy, David O, Jackson, Philippa A, Robertson, Bernadette C, Defeyter, M.A., Greer, Joanna, Scholey, Andrew B, Jackson, Philippa, Jackson, P.A., Robertson, B.C., Buchanan, Tom, Scholey, Andrew, Haskell, Crystal F, Defeyter, Margaret Anne (Greta), Haskell, C.F., Kennedy, D.O., Scholey, A.B., Elliott, J.M., Tiplady, B., Defeyter, Margaret A, Haskell, Crystal, Kennedy, David, Elliott, Jade, Robertson, Bernadette, Buchanan, T., Tiplady, Brian, Greer, J., Elliott, Jade M   +26 more
core   +1 more source

The role of biological rhythms and blood glucose levels in maintaining a positive mood state. [PDF]

, 2008
A thesis submitted in partial fulfilment of the requirements of the University of Wolverhampton for the degree of Doctor of PhilosophyAlthough the effects of both the menstrual and circadian cycles on mood have been well documented, the question of ...
Martino, Orsolina I.
core   +3 more sources