Results 41 to 50 of about 672,834 (294)

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Assessing mood in older adults : a conceptual review of methods and approaches [PDF]

, 2012
This work was supported by grant number RES354-25-0003, New Dynamics of Ageing (NDA) Programme.Background: Accurate measures of mood state are important for understanding and optimizing health and well-being in later life.
Brown, Laura, Astell, Arlene Jean, Brown, Laura J E; id_orcid, Astell, Arlene J.   +3 more
core   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

I feel good, therefore I am real: Testing the causal influence of mood on state authenticity [PDF]

, 2013
Although the literature has focused on individual differences in authenticity, recent findings suggest that authenticity is sensitive to context; that is, it is also a state.
Sedikides, Constantine, Constantine Sedikides, Slabu, Letitia, Lenton, Alison P., Katherine Power, Power, Katherine, Letitia Slabu, Lenton, Alison, Alison P. Lenton, Power, K., Lenton, A., Sedikides, C., Slabu, L.   +12 more
core   +1 more source

Relationships of affective temperament ratings to diagnosis and morbidity measures in major affective disorders

European Psychiatry, 2021
Background Ratings of affective temperament types show promise in helping to differentiate diagnostic groups among major affective disorders as well as to predict associations with important aspects of morbidity including suicidal risk.
Alessandro Miola, Ross J. Baldessarini, Marco Pinna, Leonardo Tondo   +3 more
doaj   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Biochemical and Endocrine Parameters for the Discrimination and Calibration of Bipolar Disorder or Major Depressive Disorder

Frontiers in Psychiatry, 2022
ObjectivesConventional biochemical indexes may have predictive values in clinical identification between bipolar disorder (BD) and major depressive disorder (MDD).MethodsThis study included 2,470 (BD/MDD = 1,333/1,137) hospitalized patients in Shanghai ...
Yuncheng Zhu, Yuncheng Zhu, Haifeng Ji, Zhiang Niu, Hongmei Liu, Xiaohui Wu, Lu Yang, Zuowei Wang, Jun Chen, Yiru Fang, Yiru Fang, Yiru Fang   +11 more
doaj   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Establishment and validation a relapse prediction model for bipolar disorder

Frontiers in Psychiatry
BackgroundThe recurrence rate of bipolar disorder (BD) is relatively high. Assessing the risk of relapse in patients with BD can assist in identifying populations at high risk for recurrence, and early feasible interventions can improve patient ...
Xiaoqian Zhang, Xiaoqian Zhang, Xiaoqian Zhang, Xiaoqian Zhang, Minghao Wu, Daojin Wang, Long Wang, Long Wang, Long Wang, Wen Xie, Wen Xie, Wen Xie   +11 more
doaj   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source