Results 81 to 90 of about 683,455 (344)

Mood instability : significance, definition and measurement [PDF]

, 2015
Mood instability is common, and an important feature of several psychiatric disorders. We discuss the definition and measurement of mood instability, and review its prevalence, characteristics, neurobiological correlates and clinical implications.
Broome, Matthew R., Harrison, P. J., Marwaha, Steven, Saunders, K. E. A.   +3 more
core   +1 more source

Neuropsychiatric Symptoms Mimicking Dementia in a Patient Treated With Imatinib

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Tyrosine kinase inhibitors are the cornerstone of chronic myeloid leukemia treatment. Newer agents have more potency and a broader spectrum of action, but also a higher potential for neuropsychiatric side effects. We present a case of a patient on imatinib who developed progressive cognitive, mood, and behavioral alterations.
Ashley Jones, Samuele Bonomi, Keith E. Stockerl‐Goldstein, Randall J. Bateman   +3 more
wiley   +1 more source

Biased facial emotion perception in mental health disorders:a possible target for psychological intervention? [PDF]

, 2017
Our perception of emotion in the faces of others affects our own behavior and mood. Indeed, individuals with mood disorders such as depression and aggression often show biases in facial-emotion perception.
Looi, Chung Yen, Munafo, Marcus, Penton-Voak, Ian   +2 more
core   +2 more sources

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Current and Emerging Therapies for the Management of Bipolar Disorders

Journal of Central Nervous System Disease, 2011
Bipolar disorder is a complex condition to treat because agents that may be effective for a specific phase may not be effective for other phases, or may even worsen the overall course of the illness.
Rif S. El-Mallakh, Ahmed Z. Elmaadawi, Yonglin Gao, Kavita Lohano, R. Jeannie Roberts   +4 more
doaj   +1 more source

Outpatient Management of Mood Disorders by the Family Physician [PDF]

, 2018
It is well-known that the demand for psychiatric care in the US is higher than the supply of psychiatric clinical providers. Vermont, in particular, has a paucity of psychiatric providers and there are minimal providers in Chittenden County and the ...
O\u27Neill, Elizabeth S
core   +2 more sources

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

A resource of induced pluripotent stem cell (iPSC) lines including clinical, genomic, and cellular data from genetically isolated families with mood and psychotic disorders

Translational Psychiatry, 2023
Genome-wide (GWAS) and copy number variant (CNV) association studies have reproducibly identified numerous risk alleles associated with bipolar disorder (BD), major depressive disorder (MDD), and schizophrenia (SCZ), but biological characterization of ...
Sevilla D. Detera-Wadleigh, Layla Kassem, Emily Besancon, Fabiana Lopes, Nirmala Akula, Heejong Sung, Meghan Blattner, Laura Sheridan, Ley Nadine Lacbawan, Joshua Garcia, Francis Gordovez, Katherine Hosey, Cassandra Donner, Claudio Salvini, Thomas Schulze, David T. W. Chen, Bryce England, Joanna Cross, Xueying Jiang, Winston Corona, Jill Russ, Barbara Mallon, Amalia Dutra, Evgenia Pak, Joe Steiner, Nasir Malik, Theresa de Guzman, Natia Horato, Mariana B. Mallmann, Victoria Mendes, Amanda L. Dűck, Antonio E. Nardi, Francis J. McMahon   +32 more
doaj   +1 more source

Lived and Care Experiences of Chronic Musculoskeletal Shoulder Pain in Australian Adults: A Qualitative Study

Arthritis Care &Research, EarlyView.
Objective Australian evidence on lived and care experiences of chronic musculoskeletal shoulder pain (CMSP), irrespective of disorder classification or disease, is limited. However, such evidence is important for person‐centered care and informing local service pathways and care guidelines or standards.
Sonia Ranelli, Joanne E. Jordan, Ilana N. Ackerman, Alison Thorpe, Jennifer G. Persaud, Linda J. Woodhouse, Jason Chua, Ben Horgan, Andrew M. Briggs   +8 more
wiley   +1 more source

Discontinuing psychotropic drug treatment

BJPsych Open, 2020
Interruption of ongoing treatment with benzodiazepines, antidepressants, antipsychotics and mood stabilisers including lithium can be followed by clinically significant withdrawal reactions within hours or days, as well as later increases in relapses or ...
Leonardo Tondo, Ross J. Baldessarini
doaj   +1 more source