Results 61 to 70 of about 1,494,073 (261)

Long‐Term Neurologic Exam Findings in People Diagnosed and Treated During Acute HIV Infection

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Evaluate clinical and laboratory correlates of abnormal neurologic exam findings after acute HIV infection (AHI). Methods Participants from the RV254/SEARCH 010 cohort in Bangkok underwent standardized neurologic examinations at Weeks 0 (AHI), 12, 96, and 288 following antiretroviral therapy (ART).
Kathryn B. Holroyd   +118 more
wiley   +1 more source

Classification of mood disorders

open access: yesPsychiatria Polska, 2015
This paper looks at some recent developments in the official diagnostic definitions (DSM-5) and in the research domain. The spectrum concept of mood disorders consists of the components of depression and mania, alone or in combination, on a continuum.
Angst, Jules   +2 more
openaire   +3 more sources

Modeling Progressive Brain Volume Losses in Chronic Moderate Severe Traumatic Brain Injury: Extensive, but Attenuating

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progressive brain atrophy has now been widely observed in the chronic stages of moderate–severe traumatic brain injury (msTBI), but there is only coarse information regarding its prevalence and magnitude, and whether rate of atrophy accelerates or attenuates across time. We examined these questions in a Canadian inception cohort from
Robin E. A. Green   +6 more
wiley   +1 more source

Cortisol in Mood Disorders

open access: yesStress, 2004
Dysfunction of the hypothalamic-pituitary-adrenal (HPA) axis has been well-described in mood disorders. Hypercortisolaemia, which has been attributed to a breakdown in glucocorticoid-receptor-mediated negative feedback mechanisms within the HPA axis, may be central to the pathogenesis of both the depressive symptoms and the cognitive deficits, which ...
openaire   +2 more sources

A randomized controlled trial of Internet-delivered guided and unguided cognitive behaviour therapy for treating depression and anxiety in UK university students: study protocol for the Nurture-U Internet CBT trial

open access: yesTrials
Background Tackling poor mental health in university students is a priority in higher education. Although major depressive disorder and generalized anxiety disorder are highly prevalent among university students and predict impaired university and later ...
E.R Watkins   +6 more
doaj   +1 more source

What do personality tests say about mood disorders? A systematic review

open access: yesActa Psychologica
Personality is considered a relevant factor in the development and maintenance of mood disorders. However, the use of different tests based on different theories complicates the generalization of results and the formulation of robust conclusions about ...
Jainan Rodrigues Barretto   +6 more
doaj   +1 more source

Mechanisms of rumination change in adolescent depression (RuMeChange): study protocol for a randomised controlled trial of rumination-focused cognitive behavioural therapy to reduce ruminative habit and risk of depressive relapse in high-ruminating adolescents

open access: yesBMC Psychiatry, 2021
Background Adolescent-onset depression often results in a chronic and recurrent course, and is associated with worse outcomes relative to adult-onset depression.
Henrietta Roberts   +16 more
doaj   +1 more source

Utility of the APE2 Score as a Diagnostic Tool for Autoimmune Encephalitis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To retrospectively evaluate the diagnostic performance of the Antibody Prevalence in Epilepsy and Encephalopathy (APE2) score relative to clinician‐adjudicated autoimmune encephalitis (AE) and the Graus criteria in a tertiary neuroimmunology referral cohort, including antibody‐negative AE.
Bijoya Basu   +3 more
wiley   +1 more source

Neuroplasticity in mood disorders

open access: yesDialogues in Clinical Neuroscience, 2004
Neuroimaging and neuropathological studies of major depressive disorder (MDD) and bipolar disorder (BD) have identified abnormalities of brain structure in areas of the prefrontal cortex, amygdala, striatum, hippocampus, parahippocampal gyrus, and raphe nucleus.
openaire   +3 more sources

GABA and mood disorders [PDF]

open access: yesPsychological Medicine, 2003
A γ-aminobutyric acid (GABA)-ergic theory of mood disorders was proposed by Emrich and colleagues (1980) following observations of the efficacy of the GABAergic anticonvulsant, valproate, in the treatment of mania. Since then, increasing biochemical and pharmacological evidence from animal and human studies has supported the hypothesis that mood ...
Taylor, MJ   +3 more
openaire   +5 more sources

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