Results 51 to 60 of about 1,494,073 (261)

NMDA receptor inhibition prevents intracellular sodium elevations in human olfactory neuroepithelial precursors derived from bipolar patients

open access: yesScientific Reports, 2022
Dysregulation of ion flux across membranes and glutamate-induced excitotoxicity appear to be important pathophysiologic abnormalities in bipolar illness. Understanding ion control and responses to ionic stress is important to decipher the pathogenesis of
Yonglin Gao   +4 more
doaj   +1 more source

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino   +25 more
wiley   +1 more source

Does mood affect trading behavior? [PDF]

open access: yes, 2012
We test whether investor mood affects trading with data on all stock market transactions in Finland, utilizing variation in daylight and local weather. We find some evidence that environmental mood variables (local weather, length of day, daylight saving
Markku Kaustia   +3 more
core   +1 more source

Erythromycin-induced psychotic decompensation in a patient affected by paranoid schizophrenic psychosis

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
The aim of this report is to present a case of acute psychotic decompensation in a patient suffering from paranoid schizophrenic psychosis with residual symptoms, treated with erythromycin for acute bronchitis.
Branislav Ostoja Šakić   +2 more
doaj   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova   +9 more
wiley   +1 more source

Mood Disorders [PDF]

open access: yes, 2013
Mood disorders are a crucial group of mental disorders that last for a life time, cause psychosocial dysfunction, disrupts interpersonal relationships and are overall highly restrictive.

core   +2 more sources

Indications for Dialysis in Lithium Toxicity: A Narrative Review

open access: yesKidney and Dialysis
Lithium is the most reliable mood stabilizer available for the treatment of bipolar disorder. However, its use is limited by multiple concerns, including acute toxicity.
Irem Hacisalihoglu Aydin   +5 more
doaj   +1 more source

The Efficacy of Vortioxetine on Anhedonia in Patients With Major Depressive Disorder

open access: yesFrontiers in Psychiatry, 2019
Background: Anhedonia is a common, persistent, and disabling phenomenon in treated adults with Major Depressive Disorder (MDD). Hitherto, relatively few antidepressant agents have been evaluated with respect to their effect on anhedonia in MDD.Methods ...
Bing Cao   +14 more
doaj   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon   +9 more
wiley   +1 more source

Negative mood induction effects on problem-solving task in women with eating disorders: a multi-method examination [PDF]

open access: yes, 2022
BACKGROUND: The effects of negative affect on problem-solving and its psychophysiological correlates are poorly understood in eating disorder populations.
French, Elan N.   +6 more
core   +1 more source

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