Results 31 to 40 of about 1,494,073 (261)

Clinical Consequences of Inadvertent Intramuscular Administration of Subcutaneous Risperidone Formulation

Case Reports in Psychiatry
Long-acting injectable (LAI) antipsychotics have been predominately administered intramuscularly (IM). Recently, subcutaneous (SC) formulations have been developed.
Emma Ashley, Arnela Aalomerovic, Kyle Blackmer, Rif S. El-Mallakh   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Institutional Compassion in Student Transition to University: Findings from the Nurture-U Compassionate Campus Project

Education Sciences
Compassionate university practices can increase students’ sense of belonging and lead to higher wellbeing. This study presents qualitative data from a UK university collected as part of the Nurture-U Compassionate Campus project.
Jemima Dooley, Vanessa Forbes, Amelia Green, Pranati Misurya, Polly Card, Felicity Thomas, Ed Watkins, Louise Lawrence   +7 more
doaj   +1 more source

Non-randomised feasibility study of training workshops for Talking Therapies service high-intensity therapists to optimise depression and anxiety outcomes for individuals with co-morbid personality difficulties: a study protocol

Pilot and Feasibility Studies, 2023
Background The NHS Talking Therapies for Anxiety and Depression programme (‘TTad’; formerly Improving Access to Psychological Therapies ‘IAPT’) delivers high-intensity cognitive behavioural therapy (CBT) to over 200,000 individuals each year for common ...
Laura A. Warbrick, Barnaby D. Dunn, Paul A. Moran, John Campbell, David Kessler, Katie Marchant, Michelle Farr, Mary Ryan, Megan Parkin, Richard Sharpe, Katrina Turner, Mona Sylianou, Gemma Sumner, Emma Wood   +13 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Epigenetics in mood disorders [PDF]

Environmental Health and Preventive Medicine, 2007
Depression develops as an interaction between stress and an individual's vulnerability to stress. The effect of early life stress and a gene-environment interaction may play a role in the development of stress vulnerability as a risk factor for depression.
Patrick O, McGowan, Tadafumi, Kato
openaire   +2 more sources

Manic patients and sleep management: the role of polysomnography in clinical practice

European Psychiatry, 2022
Introduction Sleep plays a key role in the pathogenesis and clinic of mood disorders. However, few studies have investigated electroencephalographic sleep parameters during the manic phases of Bipolar Disorder (BD).
F. Pacchioni, M.C. Cavallini, L. Fregna, A. Sarzetto, F. Attanasio, B. Barbini, C. Colombo   +6 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Pharmacotherapy of Personality Disorders [PDF]

, 2012
Objective: Prevalence of personality disorders have been reported as 10-13% in general population, 30-50% in psychiatric patients, and 15% in psychiatric outpatients.
Yildiz, Deniz, Oyekcin, Demet Gulec, kUTLUAY, dENİZ, GÜLEÇ ÖYEKÇİN, DEMET   +3 more
core   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source