Results 31 to 40 of about 311,073 (267)

Classification of mood disorders

Psychiatria Polska, 2015
This paper looks at some recent developments in the official diagnostic definitions (DSM-5) and in the research domain. The spectrum concept of mood disorders consists of the components of depression and mania, alone or in combination, on a continuum.
Angst, Jules, Ajdacic-Gross, Vladeta, Rössler, Wulf   +2 more
openaire   +3 more sources

Non-randomised feasibility study of training workshops for Talking Therapies service high-intensity therapists to optimise depression and anxiety outcomes for individuals with co-morbid personality difficulties: a study protocol

Pilot and Feasibility Studies, 2023
Background The NHS Talking Therapies for Anxiety and Depression programme (‘TTad’; formerly Improving Access to Psychological Therapies ‘IAPT’) delivers high-intensity cognitive behavioural therapy (CBT) to over 200,000 individuals each year for common ...
Laura A. Warbrick, Barnaby D. Dunn, Paul A. Moran, John Campbell, David Kessler, Katie Marchant, Michelle Farr, Mary Ryan, Megan Parkin, Richard Sharpe, Katrina Turner, Mona Sylianou, Gemma Sumner, Emma Wood   +13 more
doaj   +1 more source

Institutional Compassion in Student Transition to University: Findings from the Nurture-U Compassionate Campus Project

Education Sciences
Compassionate university practices can increase students’ sense of belonging and lead to higher wellbeing. This study presents qualitative data from a UK university collected as part of the Nurture-U Compassionate Campus project.
Jemima Dooley, Vanessa Forbes, Amelia Green, Pranati Misurya, Polly Card, Felicity Thomas, Ed Watkins, Louise Lawrence   +7 more
doaj   +1 more source

Manic patients and sleep management: the role of polysomnography in clinical practice

European Psychiatry, 2022
Introduction Sleep plays a key role in the pathogenesis and clinic of mood disorders. However, few studies have investigated electroencephalographic sleep parameters during the manic phases of Bipolar Disorder (BD).
F. Pacchioni, M.C. Cavallini, L. Fregna, A. Sarzetto, F. Attanasio, B. Barbini, C. Colombo   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Impact of SARS-CoV-2 Infection on Cognitive Function: A Systematic Review

Frontiers in Psychiatry, 2021
The prevalence and etiology of COVID-19's impact on brain health and cognitive function is poorly characterized. With mounting reports of delirium, systemic inflammation, and evidence of neurotropism, a statement on cognitive impairment among COVID-19 ...
Yazen Alnefeesi, Ashley Siegel, Leanna M. W. Lui, Kayla M. Teopiz, Roger C. M. Ho, Yena Lee, Flora Nasri, Hartej Gill, Kangguang Lin, Kangguang Lin, Bing Cao, Joshua D. Rosenblat, Joshua D. Rosenblat, Roger S. McIntyre, Roger S. McIntyre, Roger S. McIntyre, Roger S. McIntyre   +16 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Epilepsy and mood disorders [PDF]

Epilepsia, 2007
Summary  Mood disorders (MD) are a frequent comorbidity of epilepsy with a negative impact on quality of life. The higher prevalence of MD in people with epilepsy (PWE) is most likely a reflection of a bidirectional relation between the two conditions, and common pathogenic mechanisms.
openaire   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

A qualitative study exploring depressed participants’ experiences of receiving Augmented Depression Therapy (ADepT)

BMJ Open
Objectives The current study aimed to explore participants’ views on the acceptability, impact and mechanisms of change of Augmented Depression Therapy (ADepT), a novel wellbeing-focused and recovery-oriented psychological therapy for depression.Design A
Rebecca Watson, Kim A Wright, Nigel Reed, Barney Dunn, Emily Widnall, Kalliopi Demetriou, Laura Warbrick, Katie Marchant, Nicole Geschwind, Isabella Magner-Parsons, Rachel Barter   +10 more
doaj   +1 more source