Results 21 to 30 of about 311,073 (267)

Biochemical and Endocrine Parameters for the Discrimination and Calibration of Bipolar Disorder or Major Depressive Disorder

Frontiers in Psychiatry, 2022
ObjectivesConventional biochemical indexes may have predictive values in clinical identification between bipolar disorder (BD) and major depressive disorder (MDD).MethodsThis study included 2,470 (BD/MDD = 1,333/1,137) hospitalized patients in Shanghai ...
Yuncheng Zhu, Yuncheng Zhu, Haifeng Ji, Zhiang Niu, Hongmei Liu, Xiaohui Wu, Lu Yang, Zuowei Wang, Jun Chen, Yiru Fang, Yiru Fang, Yiru Fang   +11 more
doaj   +1 more source

Relationships of affective temperament ratings to diagnosis and morbidity measures in major affective disorders

European Psychiatry, 2021
Background Ratings of affective temperament types show promise in helping to differentiate diagnostic groups among major affective disorders as well as to predict associations with important aspects of morbidity including suicidal risk.
Alessandro Miola, Ross J. Baldessarini, Marco Pinna, Leonardo Tondo   +3 more
doaj   +1 more source

Recognition and Treatment of Cognitive Dysfunction in Major Depressive Disorder

Frontiers in Psychiatry, 2018
Major Depressive Disorder (MDD) is a prevalent, chronic, disabling, and multidimensional mental disorder. Cognitive dysfunction represents a core diagnostic and symptomatic criterion of MDD, and is a principal determinant of functional non-recovery ...
Hannah Zuckerman, Zihang Pan, Zihang Pan, Caroline Park, Caroline Park, Elisa Brietzke, Elisa Brietzke, Natalie Musial, Aisha S. Shariq, Michelle Iacobucci, Samantha J. Yim, Leanna M. W. Lui, Carola Rong, Roger S. McIntyre, Roger S. McIntyre, Roger S. McIntyre, Roger S. McIntyre, Roger S. McIntyre   +17 more
doaj   +1 more source

Cognition in mood disorders [PDF]

BJPsych Open, 2020
Cognitive impairment plays a key role in determining the course of illness and functional outcomes in mood disorders. This article summarises and discusses important papers within this thematic series of BJPsych Open that contribute to a greater understanding of the complexity of ‘Cognition in Mood Disorders’.
Katie M. Douglas, Richard J. Porter, Allan H. Young   +2 more
openaire   +3 more sources

The Burden of Mood Disorders [PDF]

Science, 2012
The Overall Burden of Mood Disorders—Individual, Societal, and Economic—has been increasing in recent decades. This is certainly the case for depression (see the special section beginning on page 67 of this issue). In Europe, the burden is greater than 10 years ago despite the availability of reasonably effective pharmacological and ...
openaire   +2 more sources

GABA and mood disorders [PDF]

Psychological Medicine, 2003
A γ-aminobutyric acid (GABA)-ergic theory of mood disorders was proposed by Emrich and colleagues (1980) following observations of the efficacy of the GABAergic anticonvulsant, valproate, in the treatment of mania. Since then, increasing biochemical and pharmacological evidence from animal and human studies has supported the hypothesis that mood ...
Taylor, MJ, Bhagwagar, Z, Cowen, PJ, Sharp, T   +3 more
openaire   +5 more sources

The THINC-it Tool for Cognitive Assessment and Measurement in Major Depressive Disorder: Sensitivity to Change

Frontiers in Psychiatry, 2020
BackgroundHerein, we sought to determine the sensitivity to change in cognitive function, as measured by the THINC-it tool, in a sample of adults with major depressive disorder (MDD) receiving standardized antidepressant therapy.MethodsAdults meeting the
Roger S. McIntyre, Roger S. McIntyre, Roger S. McIntyre, Roger S. McIntyre, Roger S. McIntyre, Mehala Subramaniapillai, Caroline Park, Caroline Park, Hannah Zuckerman, Bing Cao, Yena Lee, Yena Lee, Michelle Iacobucci, Flora Nasri, Dominika Fus, Christopher R. Bowie, Christopher R. Bowie, Tanya Tran, Joshua D. Rosenblat, Rodrigo B. Mansur, Rodrigo B. Mansur   +20 more
doaj   +1 more source

Neurocircuitry of Mood Disorders [PDF]

Neuropsychopharmacology, 2009
This review begins with a brief historical overview of attempts in the first half of the 20th century to discern brain systems that underlie emotion and emotional behavior. These early studies identified the amygdala, hippocampus, and other parts of what was termed the 'limbic' system as central parts of the emotional brain.
Joseph L, Price, Wayne C, Drevets
openaire   +2 more sources

Probing the clinical and brain structural boundaries of bipolar and major depressive disorder

Translational Psychiatry, 2021
Bipolar disorder (BD) and major depressive disorder (MDD) have both common and distinct clinical features, that pose both conceptual challenges in terms of their diagnostic boundaries and practical difficulties in optimizing treatment.
Tao Yang, Sophia Frangou, Raymond W. Lam, Jia Huang, Yousong Su, Guoqing Zhao, Ruizhi Mao, Na Zhu, Rubai Zhou, Xiao Lin, Weiping Xia, Xing Wang, Yun Wang, Daihui Peng, Zuowei Wang, Lakshmi N. Yatham, Jun Chen, Yiru Fang   +17 more
doaj   +1 more source

Association between cognitive function and performance on effort based decision making in patients with major depressive disorder treated with Vortioxetine

Comprehensive Psychiatry, 2019
Background: It is well established that deficits in motivation, reward, and cognition are common during and in between syndromal episodes of depression as part of Major Depressive Disorder (MDD).
Mehala Subramaniapillai, Rodrigo B. Mansur, Hannah Zuckerman, Caroline Park, Yena Lee, Michelle Iacobucci, Bing Cao, Roger Ho, Kangguang Lin, Lee Phan, Roger S. McIntyre   +10 more
doaj   +1 more source