Results 141 to 150 of about 93,615 (260)

Lysosomal down-regulation of the mu opioid receptor is opposed by the Retromer complex. [PDF]

Sci Adv
Dagunts A, Adoff H, Novy B, Ameur LB, De Maria M, Saunders A, Lobingier BT.   +6 more
europepmc   +1 more source

Promoting Inclusive Workplaces: Conceptualizing and Measuring Inclusive Leadership in Public Organizations

Public Administration Review, EarlyView.
ABSTRACT Inclusive leadership has become a central theme in public management research to foster equity and workplace inclusiveness. While prior studies demonstrate its potential to enhance inclusiveness, psychological safety, and performance, existing conceptualizations and measures remain fragmented, emphasizing leader attitudes rather than ...
Tanachia S. Ashikali, Mads Pieter Van Luttervelt   +1 more
wiley   +1 more source

TET1 downregulation in the dorsal root ganglion and spinal cord is required for short-term sleep disturbance to delay surgical pain recovery. [PDF]

Br J Anaesth
Cao J, Wang PK, Xu B, Gu X, Pan Z, Cai W, Su S, Li Z, Delorenzo J, Bekker A, Hu H, Tao YX.   +11 more
europepmc   +1 more source

The Gendered Path of Least Resistance: First Entry and Exit Behaviors of Public and Nonprofit Employees

Public Administration Review, EarlyView.
ABSTRACT Public and nonprofit organizations exhibit high rates of female employment often attributed to sector structures and social roles. To better understand how individual behaviors dynamically contribute to these distinctive ratios, we deconstruct public and nonprofit employment into gendered patterns of attraction and attachment.
Tiana Marrese, Ying Liu, Femida Handy
wiley   +1 more source

Urologist and radiologist contributions to variation in prostate cancer detection at fusion biopsy. [PDF]

BJU Int
Triner D, Ginsburg KB, Moser A, Labardee C, Korman H, Domina J, Cher ML, Peabody J, Semerjian A, Purysko A, George AK, Borza T, Krumm AE, Michigan Urological Surgery Improvement Collaborative (MUSIC).   +13 more
europepmc   +1 more source

Receptor Binding, Functional Activity, and Cell Viability Assessment of Novel Marine-Based Hybrid Peptides from <i>Raja porosa</i>. [PDF]

Mar Drugs
Bauer M, Szeleszczuk Ł, Velmurugan BK, Chiang SL, Laskowska AK, Pisklak DM, Szűcs E, Gombos D, Kamysz W, Fehér T, Pielaszkiewicz N, Małek K, Kleczkowska P.   +12 more
europepmc   +1 more source

G protein regulatory network shapes magnitude and kinetics of behavioral responses in an engineered opioid receptor model. [PDF]

J Biol Chem
Coleman DL, Ren RJ, Opperman KJ, Kwan EX, Martemyanov KA, Grill B.   +5 more
europepmc   +1 more source

A µ-opioid receptor superagonist analgesic with minimal adverse effects. [PDF]

Nature
Gomez JL, Ventriglia EN, Frangos ZJ, Sulima A, Robertson MJ, Sacco MD, Budinich RC, Giosan IM, Xie T, Solis O, Tischer AE, Bossert JM, Caldwell KE, Bonbrest H, Essmann A, Garçon-Poca ZM, Choi S, Noya MR, Limiac F, Arce A, Glatfelter GC, Robinson M, Chen L, Mullarkey AA, Brademan DR, Enten G, Dunne W, Quiroz C, Schoenborn I, Lee CB, Rais R, Holt DP, Dannals RF, Shi L, Hüttenhain R, Ferré S, Kiyatkin E, Bonaventura J, Shaham Y, Zachariou V, Baumann MH, Skiniotis G, Rice KC, Michaelides M.   +43 more
europepmc   +1 more source

Identification of Crucial Drug Targets and Pathways to Reprogram Drug Resistance Through Epigenetic Modulation in Advanced Lung Cancer Using Integrated Bioinformatics Approach

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Resistance to chemotherapy, which is demonstrated in almost every patient with advanced‐stage lung cancer (ALC), underscores an urgent need to unravel the underlying molecular mechanisms and identify novel strategies to overcome drug resistance. In the present study, an attempt was made to identify epigenetic targets and modulators that can be
Okibur Rahman, Mossammat Rima Akter, Nur Alam   +2 more
wiley   +1 more source

A Combined Colon Organoid-Sensory Neuron Model Reveals Epithelial Contribution to Moringin Efficacy Against Painful Inflammatory Bowel Disease. [PDF]

Phytother Res
Margiotta F, Lucarini E, Toti A, Cataldi MG, Ciampi C, De Nicola GR, Di Cesare Mannelli L, Ghelardini C.   +7 more
europepmc   +1 more source