Results 201 to 210 of about 1,011,235 (270)

Bisphenol B Exposure Induces Miscarriage by Suppressing Migration/Invasion and Migrasome Formation

Advanced Science, Volume 13, Issue 7, 3 February 2026.
BPB (Bisphenol B) exposure up‐regulates ER (estrogen receptor) levels, enhances its interactions with the lnc‐HZ04 promoter region, and thus promotes ER‐mediated lnc‐HZ04 transcription. Subsequently, lnc‐HZ04 suppresses TCF4 (transcription factor 4)‐mediated PKCA (protein kinase C alpha) transcription and subsequently suppresses migration/invasion and ...
Wenxin Huang, Manli Wang, Yi Sun, Xiaoping Yue, Xun Li, Yanbing Lin, Geng Guo, Depeng Zhao, Qigang Fan, Xiaoling Ma, Zhihong Zhang, Shuaishuai Xing, Xiaoting Shen, Huidong Zhang   +13 more
wiley   +1 more source

A Blood‐Brain Barrier‐Penetrant Ag(III) Corrole Compound Rescues Alzheimer's Disease Pathology by Targeting Aβ42‐Induced Oxidative Stress

Advanced Science, Volume 13, Issue 8, 9 February 2026.
The newly designed metallo‐corrole (Mor‐Cor)Ag(III) with a morpholino group exhibited promising therapeutic potential for Alzheimer's disease. It significantly reduces reactive oxygen species (ROS), decreases GFAP expression, increases neurite length, and decreases cell death compared to other similar metallo‐corroles. Abstract Alzheimer's disease (AD)
Arup Tarai, Tuhina Mitra, Tanmoy Pain, Jyotiprakash Mallick, Rwiddhi Chakraborty, Kallam Tejaswi, Swagata Ghatak, Sanjib Kar   +7 more
wiley   +1 more source

Mimicking opioid analgesia in cortical pain circuits. [PDF]

Nature
Oswell CS, Rogers SA, James JG, McCall NM, Hsu AI, Salimando GJ, Mahmood M, Wooldridge LM, Wachira M, Jo AY, Sandoval Ortega RA, Wojick JA, Beattie K, Farinas SA, Chehimi SN, Rodrigues A, Wu JWK, Ejoh LL, Kimmey BA, Lo E, Azouz G, Vasquez JJ, Banghart MR, Beier KT, Creasy KT, Crist RC, Ramakrishnan C, Reiner BC, Deisseroth K, Yttri EA, Corder G.   +30 more
europepmc   +1 more source

A Confirmatory Case of Severe Spondylocostal Dysostosis Caused by Biallelic Loss‐of‐Function of DMRT2

American Journal of Medical Genetics Part A, Volume 200, Issue 2, Page 496-501, February 2026.
ABSTRACT Spondylocostal dysostosis (SCDO) is a rare genetic disorder characterized by abnormal development of the axial skeleton, resulting in malformations of the vertebrae and ribs that often impair lung development and lead to significant respiratory morbidity.
Jonathan Rips, Hagar Mor‐Shaked, Oded Shamriz, Raz Somech, Rawan Abu Omar, Smadar Eventov‐Friedman, Noa Ofek‐Shlomai, Dvorah Zaguer, Tamar Harel   +8 more
wiley   +1 more source

Influence of Aluminum Distribution in Cu-MOR Systems on Methane-to-Methanol Conversion: A Combined Experimental and Theoretical Study. [PDF]

J Phys Chem C Nanomater Interfaces
Njoroge PN, Gading Solemsli B, Wijerathne A, Capel Berdiell I, Seremak A, Chiesa M, Liao YK, Garetto B, Patel N, Kvande K, Borfecchia E, Paolucci C, Olsbye U, Beato P, Svelle S, Prodinger S.   +15 more
europepmc   +1 more source

Efficient Dynamics: Reduced‐Order Modeling of the Time‐Dependent Schrödinger Equation

Advanced Physics Research, Volume 5, Issue 2, February 2026.
Reduced‐order modeling (ROM) approaches for the time‐dependent Schrödinger equation are investigated, highlighting their ability to simulate quantum dynamics efficiently. Proper Orthogonal Decomposition, Dynamic Mode Decomposition, and Reduced Basis Methods are compared across canonical systems and extended to higher dimensions.
Kolade M. Owolabi
wiley   +1 more source

Low dose naloxone mitigates opioid tolerance and dependence and restores mesenchymal stem cell function for cell therapy in addiction. [PDF]

Sci Rep
Goki MM, Rostamgohary A, Yaghoubi S, Bezenjani KE, Behroozi Z, Norouzmahani ME, Samani M, Nematollahi MH, Mehrabani M.   +8 more
europepmc   +1 more source

T‐cell receptor–like chimeric antigen receptor T cells targeting mesothelin: A first‐in‐human dose‐escalation trial for platinum‐resistant advanced ovarian cancer

Cancer, Volume 132, Issue 3, 1 February 2026.
Abstract Background Ovarian cancer remains a formidable therapeutic challenge due to late diagnosis, high recurrence rates, and limited treatment options. Mesothelin (MSLN) is highly expressed in ovarian cancer, making it a promising target for immunotherapy.
Yiyang Shan, Bo Ding, Feng Ji, Hao Lin, Weiwei Shi, Enxiu Wang, Chen Wang, Yang Shen   +7 more
wiley   +1 more source

Characterization of enzootic nasal tumor virus 1-associated enzootic nasal adenocarcinoma in sheep and development of a tumor-derived organoid model. [PDF]

J Vet Diagn Invest
Pillai VV, Ts S, Mor SK.
europepmc   +1 more source

New methods provide a 300‐year perspective on modern area burned in two wilderness areas of the southwest United States

Ecosphere, Volume 17, Issue 2, February 2026.
Abstract Climate change, expanding human ignitions, and increased fuels from fire exclusion are driving increases in area burned and fire severity in dry conifer forests of the western United States. Increasing area burned is occurring against the backdrop of a large fire deficit caused by over a century of fire exclusion.
C. A. Farris, E. Q. Margolis, J. M. Iniguez, D. A. Falk, K. G. Gerow, C. H. Baisan, C. D. Allen, T. W. Swetnam   +7 more
wiley   +1 more source