Results 61 to 70 of about 6,317 (257)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Jacobean Morality and Moral Performativity in Volpone and Women Beware Women
Ideas: Journal of English Literary Studies, 2021 In Volpone, or the Fox, Ben Jonson conveys a moral message, blending the satirical comedy with the feigning death of the protagonist Volpone, who spreads the false news of his death to the legacy hunters.
Gül Kurtuluş
doaj
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Urgensi Menjadi Teladan: Peran Guru Sebagai Role Model Dalam Pendidikan Agama Islam
Edification JournalIslamic Religious Education plays a central role in shaping individuals' character and morality. In this context, teachers not only act as educators but also as role models who provide real-life examples for students. This article explores the urgency of
M. Afiqul Adib
doaj +1 more source
Internet of Things – A New Epistemic Object [PDF]
Journal of Systemics, Cybernetics and Informatics, 2017 Within the digitalization the Internet of Things (IoT) plays an important role. The research areas of the Internet of Things, highlighting its potentialities as well as its dark sides, are discussed.
Rolf Dornberger +2 more
doaj
Cultural Assimilation: Two Ibsenian Women in Traditional Chinese Yue Opera
Interlitteraria, 2016 Chinese interest in Henrik Ibsen’s plays has flourished for more than a century and many of his plays have been performed on or adapted for the Chinese stage since the early twentieth century.
Terry Siu-Han Yip
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Akhlak Mahmudah Perspective of Ibn Miskawaih
Spiritual HealingThe moral of Mahmudah is an important point in the tradition of Islamic thought that has been explained in depth by the Islamic philosopher Ibn Miskawaih.
Jarman Arroisi +2 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source