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Moringin alleviates DSS-induced ulcerative colitis in mice by regulating Nrf2/NF-κB pathway and PI3K/AKT/mTOR pathway

International Immunopharmacology
Ulcerative colitis (UC) is a main form of inflammatory bowel disease (IBD), which is a chronic and immune-mediated inflammatory disease. Moringin (MOR) is an isothiocyanate isolated from Moringa oleifera Lam., and has been recognized as a promising potent drug for inflammatory diseases and antibacterial infections.
Tongbo Zhang   +4 more
openaire   +2 more sources

Moringin as a Lead Compound for Anti‐Enteroviruses and Coronaviruses Broad‐Spectrum Inhibition of Viral Proteases: Comparative Evaluation With Glucomoringin and Antiviral Agents

Journal of Medical Virology
ABSTRACT Enteroviruses (EVs) and Coronaviruses (CoVs) are single‐stranded RNA viruses known for their high pathogenicity and significant threat to public health worldwide. These viruses cause widespread respiratory illnesses in humans, resulting in considerable rates of sickness and death, which strain medical ...
Tzu‐Hau Shi   +5 more
openaire   +1 more source

Combined colon organoid and sensory neuron system predicts moringin efficacy against painful inflammatory bowel disease

Francesco Margiotta   +7 more
openaire   +1 more source

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