Results 51 to 60 of about 881 (169)

The Determination of the Relative Configuration of Morphine, Levorphanol and Laevo-Phenazocine by Stereoselective Adsorbents

, 1960
The preparation of levorphanol, dextrorphan and morphine stereoselective adsorbents is described. These adsorbents are used to show that the laevo isomers of morphine, phenazocine and a related compound, and racemorphan and related morphinans have ...
Patricia Anderson, A H Beckett
core   +1 more source

Spatiotemporal oscillations of morphinan alkaloids in opium poppy

Journal of Biosciences, 2018
Here, a comprehensive endeavor is made to simultaneously scrutinize spatiotemporal oscillations of three imperative morphinan alkaloids (i.e. thebaine, codeine, and morphine) alongside dynamic transcriptional patterns of TYDC, SalAT, COR, T6ODM, and CODM genes in different tissues of Papaver somniferum (i.e.
Mahdi, Rezaei, Mohammad Reza, Naghavi, Abdolhadi, Hosseinzadeh, Alireza, Abasi, Jaber, Nasiri   +4 more
openaire   +2 more sources

Enantioenriched Methylene-Bridged Benzazocanes Synthesis by Organocatalytic and Superacid Activations

, 2020
International audienceAchieving in a straightforward way the synthesis of enantioenriched elaborated three-dimensional molecules related to bioactive natural products remains a long-standing quest in organic synthesis.
Agnès Martin‐Mingot, Thibaudeau, Sébastien, Rodolphe Beaud, Jean Rodriguez, Sébastien Thibaudeau, Reviriot, Yasmin, Bastien Michelet, Martin-Mingot, Agnès, Yasmin Reviriot, Beaud, Rodolphe, Damien Bonne, Rodriguez, Jean, Michelet, Bastien, Bonne, Damien   +13 more
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Pharmacological assessment of morphinans and peptide mu-opioid receptor ligands and their application as safer pain therapeutics

, 2021
Etwa 20-30% der Weltbevölkerung leiden unter chronischen Schmerzen, jedoch können diese in vielen Fällen nur unzulänglich behandelt werden. Während für das Management geringer bis moderater Schmerzen überwiegend nichtsteroidale Antirheumatika (NSAR) zum ...
Dumitrascuta, Maria
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Synthetic analgesics.

, 1966
1. Diphenylpropylamines / by P. A. J. Janssen2A. Morphinans / by J. Hellerbach, O. Schnider, H. Besendorf e. a.2B. 6.7-Benzomorphans / by N. B. Eddy and E. L. May.Pt.
Janssen, Paul Adriaan Jan,Baron,1926-2003(viaf)32253568, Hellerbach, J.,, May, Everette Lee,1914-2008, Schnider, O.,, Besendorf, H.,, Eddy, Nathan Browne,1890-1973(viaf)24330416   +5 more
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Effect of a 6-Cyano Substituent in 14-Oxygenated N-Methylmorphinans on Opioid Receptor Binding and Antinociceptive Potency

, 2016
In a continued effort to find new substitution patterns in morphinans that would produce strong antinociception while inducing lesser side effects, 4,5-oxygen bridge-opened 6-cyano-substituted N-methylmorphinans (1−3) were synthesized.
Mario D. Aceto (2384371), Elisabeth Greiner (2089093), Helmut Schmidhammer (576205), Mariana Spetea (576206), Andrew Coop (1416964), Louis S. Harris (1290528)   +5 more
core   +1 more source

Synthesis of Novel Morphinans From Thebaine [PDF]

, 1981
The synthesis of codeinone enol ethers from thebaine, via acetals of 14beta-bromocodeinone, has been successfully carried out. These enol ethers have, in turn, been converted into 6-alkoxy-6-desmethoxy-19-alkylthevinols, which have been shown to be ...
McDougall, Duncan Campbell
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Structures of morphine, oxymorphone and N-substituted morphinans 1–6.

, 2014
Ph, phenyl.
Girolamo Calo (1601704), Szabolcs Béni (576202), Helmut Schmidhammer (576205), Tanila Ben Haddou (576201), Mariana Spetea (576206), Sándor Hosztafi (576203), Davide Malfacini (576204)   +6 more
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10-Oxo-Morphinans as Potential Kappa Selective Analgesics [PDF]

, 1993
Ethylketocyclazocine (EKC), a benzomorphan drug with a 10-oxo group, binds preferentially to kappa opiate receptors. The aim of the present research was to introduce a 10-oxo group into known, potent, mu-selective, morphinan analgesics and possibly ...
Henderson, Calum Fraser
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Synthesis of Pharmachologically Active Morphinans and Aporphines with Suzuki reaction [PDF]

, 2008
Az alkaloidkémia terültén jól elkülöníthető a Suzuki reakció szerepe: totálszintézisekben, az adott váz kiépítésében való alkalmazásánál, valamint a meglévő váz funkcionalizálásában történő felhasználása, különös tekintettel a különös tekintettel a új ...
Sipos, Attila
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