Results 241 to 250 of about 11,589 (292)

Molecular interactions between DPPC and morphine derivatives: a DSC and EPR study

open access: yesInternational Journal of Pharmaceutics, 2003
The interaction between different morphine derivatives (morphine, codeine, N-methyl-morphine, N-methyl-codeine) and a-L-dipalmitoyl phosphatidylcholine (DPPC) liposomes was studied with differential scanning calorimetry (DSC) and electron paramagnetic ...
Pal Grof
exaly   +1 more source

A comparison of the antinociceptive and temperature responses to morphine and fentanyl derivatives in rats

open access: yesArchives of Pharmacal Research, 2013
In addition to producing antinociception, opioids exert profound effects on body temperature. This study aimed at comparing antinociceptive and hyperthermic responses between two groups of mu-opioid receptor agonists: fentanyl (4-anilinopiperidine-type ...
Sonja Vučković   +2 more
exaly   +2 more sources
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Synthesis of new morphine derivatives

Pharmaceutical Chemistry Journal, 1968
D'erd' Shel'metsi   +4 more
exaly   +2 more sources

C-19 configurational assignments in some morphine derivatives by homonuclear NOE

open access: yesMagnetic Resonance in Chemistry, 1992
Azidolysis‐thermolysis of C‐19 diastereomer tosyl esters of morphine derivatives resulted in the formation of a new substituted 4‐azatetracyclo [4.4.02,4.03,8] decane ring system.
S Makleit
exaly   +2 more sources

Selective interaction of homophtalazine derivatives with morphine

European Journal of Pharmacology, 1997
Homophtalazines show specific binding sites in the nigrostriatal system and to find their target of action the interactions between these derivatives, nerisopam and girisopam, and chlorpromazine, chlordiazepoxide and morphine were assessed. The compounds did not influence the chlorpromazine induced decrease in motility and catalepsy, nor did they alter
M I, Fekete   +5 more
openaire   +2 more sources

Comparative lipophilicity of morphine derivatives

Journal of Planar Chromatography – Modern TLC, 2015
Lipophilicity is an important physicochemical characteristic of compounds having potential use in the treatment of humans and animals. Morphine and its semisynthetic derivatives have effects on mu (μ), kappa (κ), and delta (δ) opioid receptors, and their physiological, pharmacological, and therapeutic effects mainly depend on their distribution in the ...
Kalász, Huba   +5 more
openaire   +2 more sources

Luminescence characteristics of morphine derivatives

Journal of the Chemical Society, Perkin Transactions 2, 1977
A detailed study of the fluorescence and phosphorescence characteristics of morphine, diamorphine (heroin), and a number of morphine derivatives has been undertaken. Fluorescence decay times have been determined where appropriate by using a time-correlated single photon counting technique.
Alexander Bowd, James H. Turnbull
openaire   +1 more source

Color Reactions of Morphine Derivatives.

Journal of Chemical & Engineering Data, 1966
T o CHECK the specificity of various tests for heroin, several esters of morphine and dihydromorphine were synthesized. These esters were treated with color-producing reagents and the results noted in Table I. Crystalline solids were obtained in other tests and the results are listed in Table 11.
Robert G. Splies, James M. Shellow
openaire   +1 more source

Derivatives of Morphine. I. 14-Hydroxydihydromorphinone

Journal of the American Chemical Society, 1955
Ulrich Weis
exaly   +2 more sources

Biosynthesis of unnatural morphine derivatives in Papaver somniferum

Journal of the Chemical Society, Perkin Transactions 1, 1972
Demethylation of various codeine derivatives to give the corresponding, unnatural derivatives of morphine has been studied in Papaver somniferum. The efficiencies of the unnatural processes have been compared with that of the natural, codeine into morphine, conversion by feeding mixtures of [2-3H]-labelled codeine derivatives with [N-methyl-14C]codeine.
G W, Kirby, S R, Massey, P, Steinreich
openaire   +2 more sources

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