Results 241 to 250 of about 11,589 (292)
Molecular interactions between DPPC and morphine derivatives: a DSC and EPR study
The interaction between different morphine derivatives (morphine, codeine, N-methyl-morphine, N-methyl-codeine) and a-L-dipalmitoyl phosphatidylcholine (DPPC) liposomes was studied with differential scanning calorimetry (DSC) and electron paramagnetic ...
Pal Grof
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In addition to producing antinociception, opioids exert profound effects on body temperature. This study aimed at comparing antinociceptive and hyperthermic responses between two groups of mu-opioid receptor agonists: fentanyl (4-anilinopiperidine-type ...
Sonja Vučković +2 more
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Synthesis of new morphine derivatives
Pharmaceutical Chemistry Journal, 1968D'erd' Shel'metsi +4 more
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C-19 configurational assignments in some morphine derivatives by homonuclear NOE
Azidolysis‐thermolysis of C‐19 diastereomer tosyl esters of morphine derivatives resulted in the formation of a new substituted 4‐azatetracyclo [4.4.02,4.03,8] decane ring system.
S Makleit
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Selective interaction of homophtalazine derivatives with morphine
European Journal of Pharmacology, 1997Homophtalazines show specific binding sites in the nigrostriatal system and to find their target of action the interactions between these derivatives, nerisopam and girisopam, and chlorpromazine, chlordiazepoxide and morphine were assessed. The compounds did not influence the chlorpromazine induced decrease in motility and catalepsy, nor did they alter
M I, Fekete +5 more
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Comparative lipophilicity of morphine derivatives
Journal of Planar Chromatography – Modern TLC, 2015Lipophilicity is an important physicochemical characteristic of compounds having potential use in the treatment of humans and animals. Morphine and its semisynthetic derivatives have effects on mu (μ), kappa (κ), and delta (δ) opioid receptors, and their physiological, pharmacological, and therapeutic effects mainly depend on their distribution in the ...
Kalász, Huba +5 more
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Luminescence characteristics of morphine derivatives
Journal of the Chemical Society, Perkin Transactions 2, 1977A detailed study of the fluorescence and phosphorescence characteristics of morphine, diamorphine (heroin), and a number of morphine derivatives has been undertaken. Fluorescence decay times have been determined where appropriate by using a time-correlated single photon counting technique.
Alexander Bowd, James H. Turnbull
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Color Reactions of Morphine Derivatives.
Journal of Chemical & Engineering Data, 1966T o CHECK the specificity of various tests for heroin, several esters of morphine and dihydromorphine were synthesized. These esters were treated with color-producing reagents and the results noted in Table I. Crystalline solids were obtained in other tests and the results are listed in Table 11.
Robert G. Splies, James M. Shellow
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Derivatives of Morphine. I. 14-Hydroxydihydromorphinone
Journal of the American Chemical Society, 1955Ulrich Weis
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Biosynthesis of unnatural morphine derivatives in Papaver somniferum
Journal of the Chemical Society, Perkin Transactions 1, 1972Demethylation of various codeine derivatives to give the corresponding, unnatural derivatives of morphine has been studied in Papaver somniferum. The efficiencies of the unnatural processes have been compared with that of the natural, codeine into morphine, conversion by feeding mixtures of [2-3H]-labelled codeine derivatives with [N-methyl-14C]codeine.
G W, Kirby, S R, Massey, P, Steinreich
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