Results 191 to 200 of about 459,719 (297)

Global Variability in Discoid Meniscus Management: A Comparative Study of Pediatric Research in Sports Medicine Asia‐Pacific and the Surgical Cohort Outcome Registry Experience Registry

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To compare diagnostic emphasis and surgical management strategies for discoid meniscus (DM) between Asia‐Pacific surgeons participating in the Pediatric Research in Sports Medicine collaborative and North American surgeons within the Surgical Cohort Outcome Registry Experience registry.
Si Jian Hui, Khim Yew Chew, Jacqueline Jin Li Liew, Ryan Wai Keong Loke, Henry Ellis, Qi‐Wei Lee, James Hoi Po Hui   +6 more
wiley   +1 more source

Modeling NDD-Associated NLGN2 Depletion Using CRISPR/Cas13 Reveals Exaggerated Process Elongation Mediated by the CCDC88A-G Protein-ELMO Axis. [PDF]

Int J Mol Sci
Yako H, Takahashi M, Tada S, Waragai M, Miyamoto Y, Yamauchi J.   +5 more
europepmc   +1 more source

Human Fibroblast–Myeloid Cell Tissue Atlas Across the Lungs, Synovium, Skin, and Heart

Arthritis &Rheumatology, EarlyView.
Objective The availability of single‐cell RNA sequencing (scRNAseq) data in different tissues and disease states provides an opportunity to compare cellular subsets and identify common and unique cellular activation. In this study, we aimed to characterize shared and tissue‐specific myeloid and stromal phenotypes and to uncover key cellular subtypes ...
Lucy MacDonald, Katerina Apostolopoulou, Olympia Hardy, Melpomeni Toitou, Gabriela Kania, Przemyslaw Blyszczuk, Raphael Micheroli, Thomas D. Otto, Mariola Kurowska‐Stolarska, Caroline Ospelt   +9 more
wiley   +1 more source

Primordial cardiomyocytes orchestrate myocardial morphogenesis and vascularization but are dispensable for regeneration. [PDF]

Elife
Sun J, Chen L, Wang J.
europepmc   +1 more source

IgG Glycosylation‐Dependent CLEC7A Signaling Drives Podocyte Dysfunction in Lupus Nephritis

Arthritis &Rheumatology, EarlyView.
Objective Lupus nephritis (LN) is a severe complication of systemic lupus erythematosus (SLE) that can lead to end‐stage kidney disease and increased mortality. IgG from patients with LN displays abnormal glycosylation, contributing to podocyte injury.
Rohit Upadhyay, Alexia Orellana, George C. Tsokos, Rhea Bhargava   +3 more
wiley   +1 more source

Loss of Hippo Signaling Causes Coloboma via Steric Obstruction of Optic Fissure Fusion. [PDF]

Invest Ophthalmol Vis Sci
Neelathi UM, Sanchez-Mendoza D, Steele SR, Aguda R, Brooks BP.   +4 more
europepmc   +1 more source

Treatment‐Driven Peripheral Blood Transcriptomic Remodeling and Baseline Predictors of ESSDAI and STAR Response to B Cell Therapy in Sjögren's Disease

Arthritis &Rheumatology, EarlyView.
Graphical Abstract Objective This study aimed to characterize whole blood transcriptomic profiles in adults with active Sjögren's disease (SjD) treated with anti‐CD20 or B lymphocyte stimulator/BAFF inhibition, identify markers of clinical response, and define inflammatory pathways linked to nonresponse. Methods Whole blood RNA sequencing was performed
Aimen Ibrahim, Junjie Peng, Eileen Tian, Lucia Martin‐Gutierrez, John Casement, Kyle Thompson, Wan‐Fai Ng, André van Maurik, Elizabeth C. Jury, Coziana Ciurtin   +9 more
wiley   +1 more source

Decoding Long Noncoding RNAs in Cardiac Development and Congenital Heart Disease: Recent Advances and Clinical Perspectives. [PDF]

Circ Genom Precis Med
Zhang Y, Lusis AJ, Touma M.
europepmc   +1 more source

Optimized micro‐sized cell sphere‐matrix niche co‐aggregates promote efficient oral and craniomaxillofacial bone regeneration

BMEMat, EarlyView.
The construct of cell‐niche co‐aggregates (GelMA‐SHED sphere‐DDMPs) promotes cranial and periodontal bone regeneration and ensures angiogenic‐osteogenic coupling by downregulating miR‐34c‐5p to enhance the expression of NOTCH1 and its intracellular domain (NICD).
Xiao‐Hui Zhang, Shi‐Han Mu, Yi‐Han Xiao, Lu‐Fan Yang, Peng‐Fei Wang, Teng‐Fei Hu, Jun‐Xi He, Jiong‐Zhen Piao, Sha Zhang, Jin‐Yu Liu, Yi‐De He, Ying‐Ying Wu, Si‐Qi Ying, Xin‐Yue Cai, Chen‐Han Li, Zi‐Qi Zhang, Xiao Lei, Ji Chen, Jian‐Fei Liang, Yan Jin, Bing‐Dong Sui, Chao Ma, Chen‐Xi Zheng, Fang Jin   +23 more
wiley   +1 more source

Glycolytic suppression of cell adhesion promotes thyroid morphogenesis in response to nutrition. [PDF]

EMBO Rep
Shindo A, Nishiguchi S, Fujiwara A, Nakashima K.   +3 more
europepmc   +1 more source