Results 201 to 210 of about 654,596 (326)

Reconfiguration of Multiphase Coacervate Droplets Into Self‐Regulated Nested Artificial Cells

open access: yesAngewandte Chemie, EarlyView.
Living cells advance functionality through spatiotemporal sub‐compartmentalization and internal organization. Herein, we develop a self‐regulated artificial cell by transforming a membrane‐less multiphase coacervate droplet (MCD) into a membranized, structurally reinforced nested coacervate vesicle (NCV).
Zhuping Yin   +4 more
wiley   +2 more sources

Spatial Relations between Coccoliths and Their Confining Membrane During Crystal Morphogenesis. [PDF]

open access: yesJ Am Chem Soc
Avrahami EM   +11 more
europepmc   +1 more source

Unveiling a New Link: Cholesterol Deficiency in Smith–Lemli–Opitz and Niemann–Pick C as a Driver of Ciliopathies

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The ciliopathies are a group of genetic disorders caused by defective function of either the primary cilia (a large number) or the motile cilia (a much smaller number). These have been defined as diseases with mutations in genes encoding individual ciliary or cilia‐associated proteins.
Robert P. Erickson   +1 more
wiley   +1 more source

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam   +4 more
wiley   +1 more source

The HCMV‐encoded miR‐UL36‐3p promotes angiogenesis of endothelial cells by downregulating FOXO3

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This illustration shows the role of hcmv‐miR‐UL36‐3p in endothelial cell angiogenesis. During productive infection, endothelial cells express HCMV‐encoded miRNAs. Viral hcmv‐miR‐UL36‐3p promotes endothelial cell proliferation, migration, and capillary tube formation by directly targeting and downregulating FOXO3. The pro‐angiogenic activity of hcmv‐miR‐
Chen Wang   +5 more
wiley   +1 more source

Lgr5⁺ cells regulate small intestinal morphogenesis before villification. [PDF]

open access: yesCell Regen
Zhao L   +6 more
europepmc   +1 more source

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