Mitochondria‐endoplasmic reticulum contact sites (MERCS) are areas where the mitochondria and endoplasmic reticulum closely interact. In this study, we utilize synthetic organelle glues to artificially engineer MERCS for regulating cardiomyocyte development, through which the immature and chemo‐plasticity issues of undifferentiated cells are addressed.
Wei Tang +9 more
wiley +1 more source
Swimming Upstream to Understand Congenital Anomalies of the Kidney and Urinary Tract: Zebrafish Models for Developmental Biology, Disease Mechanisms, and Functional Interpretation of Genetic Variation. [PDF]
Nurcombe ZW, Mougharbel L, Kitzler TM.
europepmc +1 more source
Integrating chemo‐mechanical cues in nano‐microscale environments for stem cell regulation
Nano/microscale control strategies, including nano/microscale materials, ligand spacings, and cell encapsulating gels, cell mechanics, integrin signaling, and biochemical cues to direct stem cell fate, tissue regeneration, and organoid engineering, enabling advanced biomedical applications through mechanoregulation at cell‐material interfaces ...
Rajendra K. Singh +5 more
wiley +1 more source
Signaling Through Girdin Underlies Excessive Cell Morphogenesis Resulting from Depletion of Neurodevelopmental Disorder-Related Neurexin-2. [PDF]
Yako H +5 more
europepmc +1 more source
Substrate stiffness with different dimensions (2D and 3D) exerts a regulatory role in cellular behaviors, thereby governing cell fate decisions. Biomaterials with tunable stiffness exhibit substantial functional potential for the repair and regeneration of the motor system.
Zhiyuan Lu +6 more
wiley +1 more source
Grooved Surface of the Obturator Internus Muscle With Two Distinct Adjacent Parts
ABSTRACT The specific anatomical features of the obturator internus, particularly those of its medial surface, remain insufficiently characterized. This study investigated the morphology of the obturator internus muscle by focusing on the shape of its medial surface and potential age‐related changes.
Satoru Muro +4 more
wiley +1 more source
Engrailed-1 in eccrine sweat gland development and regeneration: from evolutionary innovation to therapeutic perspectives. [PDF]
Zhang L +8 more
europepmc +1 more source
Labeling Strategies for Monitoring Cytoskeleton Dynamics in Cultured Epithelial Cells
ABSTRACT Collective cell migration relies on coordinated cytoskeletal remodeling, yet the impact of live‐cell actin filament probes on these dynamics remains poorly characterized. Here, we systematically compared the performance and cellular effects of fluorogenic jasplakinolide‐based probes, SiR‐actin and SiR‐XActin, with the genetically encoded ...
Victoria Levario‐Diaz +6 more
wiley +1 more source
Transcriptome Dynamics of Terminal Buds During Flower Bud Morphogenesis in Blueberry. [PDF]
Lu X +5 more
europepmc +1 more source
Abstract Background Dentitions have diversified enormously during vertebrate evolution, involving reductions, modifications, or allocations to prey seizing and processing regions. A combination of ancient and novel features related to dental and oropharyngeal apparatuses is found in extant lineages of non‐teleost fishes, such as the gars.
Anna Pospisilova +4 more
wiley +1 more source

