Results 101 to 110 of about 281,619 (271)

Simulation Frameworks for Morphogenetic Problems

open access: yesComputation, 2015
Morphogenetic modelling and simulation help to understand the processes by which the form and shapes of organs (organogenesis) and organisms (embryogenesis) emerge.
Simon Tanaka
doaj   +1 more source

Buckling without bending: a new paradigm in morphogenesis

open access: yes, 2018
A curious feature of organ and organoid morphogenesis is that in certain cases, spatial oscillations in the thickness of the growing "film" are out-of-phase with the deformation of the slower-growing "substrate," while in other cases, the oscillations ...
Engstrom, T. A.   +4 more
core   +1 more source

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

open access: yesAdvanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram   +10 more
wiley   +1 more source

Towards an automated analysis of video-microscopy images of fungal morphogenesis

open access: yesAnales del Jardín Botánico de Madrid, 2005
Fungal morphogenesis is an exciting field of cell biology and several mathematical models have been developed to describe it. These models require experimental evidences to be corroborated and, therefore, there is a continuous search for new microscopy ...
Javier Diéguez-Uribeondo   +4 more
doaj   +1 more source

Development of a Synthetic Hydrogel to Foster Microvascularization of an Endometriosis Microphysiological System

open access: yesAdvanced Healthcare Materials, EarlyView.
ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett   +7 more
wiley   +1 more source

Perivascular Progenitor Cells Derived From Human Embryonic Stem Cells Exhibit Functional Characteristics of Pericytes and Improve the Retinal Vasculature in a Rodent Model of Diabetic Retinopathy

open access: yesStem Cells Translational Medicine, 2016
Diabetic retinopathy (DR) is the leading cause of blindness in working‐age people. Pericyte loss is one of the pathologic cellular events in DR, which weakens the retinal microvessels.
Jung Mo Kim   +6 more
doaj   +1 more source

Melt Electrowriting High Resolution Poly(ethylene‐co‐vinyl acetate) Scaffolds for Soft Tissue Engineering

open access: yesAdvanced Healthcare Materials, EarlyView.
This work pioneers melt electrowriting (MEW) of polyethylene vinyl acetate (PEVA) to fabricate ultra‐compliant, high‐resolution scaffolds. By integrating microscale precision with soft tissue‐like biomechanics, PEVA overcomes stiffness‐driven limitations of conventional MEW polymers, establishing a mechanically biomimetic platform for soft tissue ...
Finn Snow   +9 more
wiley   +1 more source

Integrin-linked kinase controls retinal angiogenesis and is linked to Wnt signaling and exudative vitreoretinopathy

open access: yesNature Communications, 2019
Integrin-linked kinase (ILK) is an important mediator of integrin signaling. Here Park et al. show that mice with endothelial-specific deletion of Ilk develop vascular defects that resemble familial exudative vitreoretinopathy, and identify mutations in ...
Hongryeol Park   +12 more
doaj   +1 more source

Supramolecular Engineering of Fluid Pressure in Filamentous Hybrid Double Network Hydrogels for 3D Chondrocyte Culture

open access: yesAdvanced Healthcare Materials, EarlyView.
Inspired by the water‐rich and interconnected biopolymer networks of native load‐bearing tissues, we disclose a connectable design for a hybrid filamentous supramolecular and covalent double network hydrogel generated through in situ photopolymerization.
Ciqing Tong   +11 more
wiley   +1 more source

Active dynamics of tissue shear flow

open access: yes, 2016
We present a hydrodynamic theory to describe shear flows in developing epithelial tissues. We introduce hydrodynamic fields corresponding to state properties of constituent cells as well as a contribution to overall tissue shear flow due to ...
Eaton, Suzanne   +6 more
core   +4 more sources

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