Results 51 to 60 of about 6,133,036 (272)

A digital 3D reference atlas reveals cellular growth patterns shaping the Arabidopsis ovule

eLife, 2021
A fundamental question in biology is how morphogenesis integrates the multitude of processes that act at different scales, ranging from the molecular control of gene expression to cellular coordination in a tissue.
Athul Vijayan, Rachele Tofanelli, Sören Strauss, Lorenzo Cerrone, Adrian Wolny, Joanna Strohmeier, Anna Kreshuk, Fred A Hamprecht, Richard S Smith, Kay Schneitz   +9 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Wnt/β-catenin regulates an ancient signaling network during zebrafish scale development

eLife, 2018
Understanding how patterning influences cell behaviors to generate three dimensional morphologies is a central goal of developmental biology. Additionally, comparing these regulatory mechanisms among morphologically diverse tissues allows for rigorous ...
Andrew J Aman, Alexis N Fulbright, David M Parichy   +2 more
doaj   +1 more source

Actuation enhances patterning in human neural tube organoids

Nature Communications, 2021
Mechanical forces, along with gene regulatory networks and cell-cell signalling, play an important role in the complex organization of tissues.
Abdel Rahman Abdel Fattah, Brian Daza, Gregorius Rustandi, Miguel Ángel Berrocal-Rubio, Benjamin Gorissen, Suresh Poovathingal, Kristofer Davie, Jorge Barrasa-Fano, Mar Cóndor, Xuanye Cao, Derek Hadar Rosenzweig, Yunping Lei, Richard Finnell, Catherine Verfaillie, Maurilio Sampaolesi, Peter Dedecker, Hans Van Oosterwyck, Stein Aerts, Adrian Ranga   +18 more
doaj   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

From START to FINISH : the influence of osmotic stress on the cell cycle [PDF]

, 2013
Peer ...
Celso Grebogi, Romano, M Carmen, Neil A. R. Gow (43882), Gow, Neil A R, Radmaneshfar Elahe, Romano, Maria Carmen, Alistair J. P. Brown (108565), Elahe Radmaneshfar (432585), Grebogi, Celso, Marco Thiel (201071), M. Carmen Romano (201070), Thiel, Marco, Michael C. Gustin (432587), Gustin Michael C., Despoina Kaloriti (432586), Romano, M.Carmen, Gow, Neil A. R., Romano M. Carmen, Gow, Neil A.R., Gow Neil A. R., Kaloriti, Despoina, Alistair J P Brown, M Carmen Romano, Thiel Marco, Radmaneshfar, Elahe, Marco Thiel, Celso Grebogi (129108), Elahe Radmaneshfar, Kaloriti Despoina, Despoina Kaloriti, Brown, Alistair J.P., Brown, Alistair J P, Gustin, Michael C., Grebogi Celso, Brown, Alistair J. P., Brown Alistair J. P., Gustin, Michael C, Michael C Gustin, Neil A R Gow   +38 more
core   +1 more source

ATP‐Mediated Bidirectional Communication Between Natural and Artificial Cells for Controlled Bioreactions

Advanced Functional Materials, EarlyView.
Establishment of bidirectional communication behavior between natural and artificial cells. The first type of communication from natural dendritic cells to artificial polymeric cells was achieved via ATP release after cell lysis. The released ATP was taken up via gated UV‐controlled permeability increase of the polymeric membrane for performing ...
Ilona Kalte, Tsvetomir Ivanov, Leonhard Seufert, Shoupeng Cao, Lucas Caire da Silva, Volker Mailänder, Katharina Landfester   +6 more
wiley   +1 more source

Pericytes are organ-specific regulators of tissue morphogenesis

Nature Communications
Endothelial cells lining the vessel network are indispensable for vascular transport but also provide paracrine signals controlling the behavior of nearby cell types. Pericytes are another essential component of the vessel wall, but little is known about
Seyed Javad Rasouli, Kai Kruse, Rodrigo Diéguez-Hurtado, Parisa Ghanbari, Anusha Aravamudhan, Mara E. Pitulescu, Ralf H. Adams   +6 more
doaj   +1 more source

Fused embryos and pre-metamorphic conjoined larvae in a broadcast spawning reef coral [v2; ref status: indexed, http://f1000r.es/54p]

F1000Research, 2015
Fusion of embryos or larvae prior to metamorphosis is rarely known to date in colonial marine organisms. Here, we document for the first time that the embryos of the broadcast spawning coral Platygyra daedalea could fuse during blastulation and further ...
Lei Jiang, Xin-Ming Lei, Sheng Liu, Hui Huang   +3 more
doaj   +1 more source

The unappreciated generative role of cell movements in pattern formation

Royal Society Open Science, 2022
The mechanisms underpinning the formation of patterned cellular landscapes has been the subject of extensive study as a fundamental problem of developmental biology.
Timothy Fulton, Berta Verd, Benjamin Steventon   +2 more
doaj   +1 more source