Results 31 to 40 of about 6,133,036 (272)

Transcriptional regulation of endothelial cell behavior during sprouting angiogenesis

Nature Communications, 2017
Angiogenesis is a complex process that requires coordinated changes in endothelial cell behavior. Here the authors use Ribo-tag and RNA-Seq to determine temporal profiles of transcriptional activity during postnatal retinal angiogenesis, identifying ...
Hyun-Woo Jeong, Benjamín Hernández-Rodríguez, JungMo Kim, Kee-Pyo Kim, Rocio Enriquez-Gasca, Juyong Yoon, Susanne Adams, Hans R. Schöler, Juan M. Vaquerizas, Ralf H. Adams   +9 more
doaj   +1 more source

Nel positively regulates the genesis of retinal ganglion cells by promoting their differentiation and survival during development [PDF]

, 2014
Peer ...
Findlay, Amy S., Ouyang, Zhufeng, Zakrewska, Ewa, Kuan, Soh-Leh, Durward, Elaine, Nakamoto, Masaru, Findlay, Amy, Zakrzewska, Ewa, Nakamoto, Chizu, Kuan, Soh Leh, Endo, Takuma   +10 more
core   +1 more source

Morphogenesis in Drosophila melanogaster : an in vitro analysis [PDF]

, 2007
The aim of this thesis was to investigate morphogenesis in the fruit fly Drosophila melanogaster using three in vitro tissue culture systems. Primary embryonic cultures derived from Drosophila melanogaster were used to study the effect of the moulting
Scarborough, Julie
core   +2 more sources

Unified quantitative characterization of epithelial tissue development

eLife, 2015
Understanding the mechanisms regulating development requires a quantitative characterization of cell divisions, rearrangements, cell size and shape changes, and apoptoses.
Boris Guirao, Stéphane U Rigaud, Floris Bosveld, Anaïs Bailles, Jesús López-Gay, Shuji Ishihara, Kaoru Sugimura, François Graner, Yohanns Bellaïche   +8 more
doaj   +1 more source

A selection-based knockout approach for a choanoflagellate reveals regulation of multicellular development by Hippo signaling

Cell Reports
Summary: Choanoflagellates, the closest living relatives of animals, provide crucial insights into animal origins. The multicellular choanoflagellate Salpingoeca rosetta can be genetically modified, but existing knockout (KO) pipelines are time consuming
Chantal Combredet, Mylan Ansel, Thibaut Brunet   +2 more
doaj   +1 more source

Comparative transcriptome analyses of the Drosophila pupal eye

G3: Genes, Genomes, Genetics, 2020
Tissue function is dependent on correct cellular organization and behavior. As a result, the identification and study of genes that contribute to tissue morphogenesis is of paramount importance to the fields of cell and developmental biology. Many of the
Miles W DeAngelis, Joseph D Coolon, Ruth I Johnson   +2 more
doaj   +1 more source

Live imaging of echinoderm embryos to illuminate evo-devo

Frontiers in Cell and Developmental Biology, 2022
Echinoderm embryos have been model systems for cell and developmental biology for over 150 years, in good part because of their optical clarity. Discoveries that shaped our understanding of fertilization, cell division and cell differentiation were only ...
Vanessa Barone, Deirdre C. Lyons
doaj   +1 more source

The kinase regulator mob1 acts as a patterning protein for stentor morphogenesis. [PDF]

PLoS Biology, 2014
Morphogenesis and pattern formation are vital processes in any organism, whether unicellular or multicellular. But in contrast to the developmental biology of plants and animals, the principles of morphogenesis and pattern formation in single cells ...
Mark M Slabodnick, J Graham Ruby, Joshua G Dunn, Jessica L Feldman, Joseph L DeRisi, Wallace F Marshall   +5 more
doaj   +1 more source

The Meckel-Gruber syndrome protein TMEM67 controls basal body positioning and epithelial branching morphogenesis in mice via the non-canonical Wnt pathway. [PDF]

, 2015
Ciliopathies are a group of developmental disorders that manifest with multi-organ anomalies. Mutations in TMEM67 (MKS3) cause a range of human ciliopathies, including Meckel-Gruber and Joubert syndromes.
Daniel J. Jagger, Zakia A. Abdelhamed, Johnson, CA, Carmel Toomes, Jagger, DJ, Johnson, Colin A., Toomes, C, Wheway, G, Christopher F. Inglehearn, Colin A. Johnson, Jagger, Daniel J., Toomes, Carmel, Abdelhamed, ZA, Abdelhamed, Zakia A., Subaashini Natarajan, Inglehearn, CF, Natarajan, Subaashini, Gabrielle Wheway, Inglehearn, Christopher F., Natarajan, S, Inglehearn, Chris F., Wheway, Gabrielle   +21 more
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Modelling cell movement, cell differentiation, cell sorting and proportion regulation in Dictyostelium discoideum aggregations [PDF]

, 2015
Understanding the mechanisms that control tissue morphogenesis and homeostasis is a central goal not only in developmental biology but also has great relevance for our understanding of various diseases, including cancer.
Weijer, C. J.; id_orcid, Pineda, M., Eftimie, R.   +2 more
core   +1 more source