Results 31 to 40 of about 281,619 (271)

A modified Oster-Murray-Harris mechanical model of morphogenesis [PDF]

open access: yes, 2013
There are two main modeling paradigms for biological pattern formation in developmental biology: chemical prepattern models and cell aggregation models. This paper focuses on an example of a cell aggregation model, the mechanical model developed by Oster,
Benjamin L. Vaughan   +6 more
core   +1 more source

Transcriptional regulation of endothelial cell behavior during sprouting angiogenesis

open access: yesNature Communications, 2017
Angiogenesis is a complex process that requires coordinated changes in endothelial cell behavior. Here the authors use Ribo-tag and RNA-Seq to determine temporal profiles of transcriptional activity during postnatal retinal angiogenesis, identifying ...
Hyun-Woo Jeong   +9 more
doaj   +1 more source

Unified quantitative characterization of epithelial tissue development

open access: yeseLife, 2015
Understanding the mechanisms regulating development requires a quantitative characterization of cell divisions, rearrangements, cell size and shape changes, and apoptoses.
Boris Guirao   +8 more
doaj   +1 more source

Comparative transcriptome analyses of the Drosophila pupal eye

open access: yesG3: Genes, Genomes, Genetics, 2020
Tissue function is dependent on correct cellular organization and behavior. As a result, the identification and study of genes that contribute to tissue morphogenesis is of paramount importance to the fields of cell and developmental biology. Many of the
Miles W DeAngelis   +2 more
doaj   +1 more source

Live imaging of echinoderm embryos to illuminate evo-devo

open access: yesFrontiers in Cell and Developmental Biology, 2022
Echinoderm embryos have been model systems for cell and developmental biology for over 150 years, in good part because of their optical clarity. Discoveries that shaped our understanding of fertilization, cell division and cell differentiation were only ...
Vanessa Barone, Deirdre C. Lyons
doaj   +1 more source

A selection-based knockout approach for a choanoflagellate reveals regulation of multicellular development by Hippo signaling

open access: yesCell Reports
Summary: Choanoflagellates, the closest living relatives of animals, provide crucial insights into animal origins. The multicellular choanoflagellate Salpingoeca rosetta can be genetically modified, but existing knockout (KO) pipelines are time consuming
Chantal Combredet   +2 more
doaj   +1 more source

The kinase regulator mob1 acts as a patterning protein for stentor morphogenesis. [PDF]

open access: yesPLoS Biology, 2014
Morphogenesis and pattern formation are vital processes in any organism, whether unicellular or multicellular. But in contrast to the developmental biology of plants and animals, the principles of morphogenesis and pattern formation in single cells ...
Mark M Slabodnick   +5 more
doaj   +1 more source

Unraveling Heterogeneity in Epithelial Cell Fates of the Mammary Gland and Breast Cancer. [PDF]

open access: yes, 2019
Fluidity in cell fate or heterogeneity in cell identity is an interesting cell biological phenomenon, which at the same time poses a significant obstacle for cancer therapy.
Doh, Hanna   +3 more
core   +1 more source

The receptor protein tyrosine phosphatase PTPRB negatively regulates FGF2-dependent branching morphogenesis [PDF]

open access: yes, 2017
PTPRB is a transmembrane protein tyrosine phosphatase known to regulate blood vessel remodelling and angiogenesis. Here we demonstrate that PTPRB negatively regulates branching morphogenesis in the mammary epithelium.
Gusterson, Barry A.   +9 more
core   +3 more sources

Various scenarios of the cell pattern formation in Arabidopsis lateral root

open access: yesActa Societatis Botanicorum Poloniae, 2014
During lateral root (LR) development a coordinate sequence of cell divisions, accompanied by a change of the organ form takes place. Both the order of anatomical events and morphological features may vary for individual primordia.
Jolanta Białek   +2 more
doaj   +1 more source

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