Results 11 to 20 of about 174,983 (236)

Thyroid hormone receptor α controls larval intestinal epithelial cell death by regulating the CDK1 pathway

Communications Biology, 2022
Tanizaki et al use ChIP-Seq to identify over 3000 Thyroid hormone (T3) receptor (TR)-bound genes in the intestine of premetamorphic wild type Xenopus tropicalis tadpoles and in TRα-knockouts.
Yuta Tanizaki, Hongen Zhang, Yuki Shibata, Yun-Bo Shi   +3 more
doaj   +1 more source

Flow Dynamics and HSPC Homing in Bone Marrow Microvessels

Cell Reports, 2017
Measurements of flow velocities at the level of individual arterial vessels and sinusoidal capillaries are crucial for understanding the dynamics of hematopoietic stem and progenitor cell homing in the bone marrow vasculature.
M. Gabriele Bixel, Anjali P. Kusumbe, Saravana K. Ramasamy, Kishor K. Sivaraj, Stefan Butz, Dietmar Vestweber, Ralf. H. Adams   +6 more
doaj   +1 more source

Dynein-Mediated Regional Cell Division Reorientation Shapes a Tailbud Embryo

iScience, 2020
Summary: Regulation of cell division orientation controls the spatial distribution of cells during development and is essential for one-directional tissue transformation, such as elongation. However, little is known about whether it plays a role in other
Ayaki Nakamoto, Gaku Kumano
doaj   +1 more source

Cysteine Dioxygenase Regulates the Epithelial Morphogenesis of Mammary Gland via Cysteine Sulfinic Acid

iScience, 2019
Summary: Epithelial morphogenesis is a common feature in various organs and contributes to functional formation. However, the molecular mechanisms behind epithelial morphogenesis remain largely unknown.
Jianjun Zhao, Yuzhu Han, Xingyu Ma, Yang Zhou, Shukai Yuan, Qian Shen, Guogen Ye, Hongrun Liu, Penghui Fu, Gongwei Zhang, Bingke Qiao, Anfang Liu   +11 more
doaj   +1 more source

ultraLM and miniLM: Locator tools for smart tracking of fluorescent cells in correlative light and electron microscopy [version 1; referees: 2 approved, 1 approved with reservations]

Wellcome Open Research, 2016
In-resin fluorescence (IRF) protocols preserve fluorescent proteins in resin-embedded cells and tissues for correlative light and electron microscopy, aiding interpretation of macromolecular function within the complex cellular landscape.
Elisabeth Brama, Christopher J. Peddie, Gary Wilkes, Yan Gu, Lucy M. Collinson, Martin L. Jones   +5 more
doaj   +1 more source

Oxygen changes drive non-uniform scaling in Drosophila melanogaster embryogenesis [version 1; referees: 2 approved, 1 approved with reservations]

F1000Research, 2015
We previously demonstrated that, while changes in temperature produce dramatic shifts in the time elapsed during Drosophila melanogaster embryogenesis, the relative timing of events within embryogenesis does not change.
Steven G. Kuntz, Michael B. Eisen
doaj   +1 more source

LocalZProjector and DeProj: a toolbox for local 2D projection and accurate morphometrics of large 3D microscopy images

BMC Biology, 2021
Background Quantitative imaging of epithelial tissues requires bioimage analysis tools that are widely applicable and accurate. In the case of imaging 3D tissues, a common preprocessing step consists of projecting the acquired 3D volume on a 2D plane ...
Sébastien Herbert, Léo Valon, Laure Mancini, Nicolas Dray, Paolo Caldarelli, Jérôme Gros, Elric Esposito, Spencer L. Shorte, Laure Bally-Cuif, Nathalie Aulner, Romain Levayer, Jean-Yves Tinevez   +11 more
doaj   +1 more source

Human Intestinal Morphogenesis Controlled by Transepithelial Morphogen Gradient and Flow-Dependent Physical Cues in a Microengineered Gut-on-a-Chip

iScience, 2019
Summary: We leveraged a human gut-on-a-chip (Gut Chip) microdevice that enables independent control of fluid flow and mechanical deformations to explore how physical cues and morphogen gradients influence intestinal morphogenesis.
Woojung Shin, Christopher D. Hinojosa, Donald E. Ingber, Hyun Jung Kim   +3 more
doaj   +1 more source

Evidence of a possible multicellular life cycle in Escherichia coli

iScience, 2023
Summary: Biofilms are surface-attached multicellular microbial communities. Their genetics have been extensively studied, but the cell-scale morphogenetic events of their formation are largely unknown.
Devina Puri, Xin Fang, Kyle R. Allison
doaj   +1 more source

Brain-specific lipoprotein receptors interact with astrocyte derived apolipoprotein and mediate neuron-glia lipid shuttling

Nature Communications, 2021
Lipophorin receptors (LpRs) regulate structural and functional development of neurons in Drosophila. Here authors demonstrate how short isoforms of LpR1 mediates astrocyte lipid shuttling to neuron through interacting with glia lipoprotein GLaz and the ...
Jun Yin, Emma Spillman, Ethan S. Cheng, Jacob Short, Yang Chen, Jingce Lei, Mary Gibbs, Justin S. Rosenthal, Chengyu Sheng, Yuki X. Chen, Kelly Veerasammy, Tenzin Choetso, Rinat Abzalimov, Bei Wang, Chun Han, Ye He, Quan Yuan   +16 more
doaj   +1 more source