Results 21 to 30 of about 281,619 (271)

Oxygen changes drive non-uniform scaling in Drosophila melanogaster embryogenesis [version 1; referees: 2 approved, 1 approved with reservations]

F1000Research, 2015
We previously demonstrated that, while changes in temperature produce dramatic shifts in the time elapsed during Drosophila melanogaster embryogenesis, the relative timing of events within embryogenesis does not change.
Steven G. Kuntz, Michael B. Eisen
doaj   +1 more source

Regulation of polarised growth in fungi [PDF]

, 2008
Polarised growth in fungi occurs through the delivery of secretory vesicles along tracks formed by cytoskeletal elements to specific sites on the cell surface where they dock with a multiprotein structure called the exocyst before fusing with the ...
Adamo, Adamo, Adams, Akashi, Ayad-Durieux, Bachewich, Bartnicki-Garcia, Bartnicki-Garcia, Bassilana, Bassilana, Bassilana, Behrens, Berman, Bidlingmaier, Bose, Boyce, Boyce, Boyce, Boyd, Brown, Caviston, Chant, Chapa y Lazo, Collinge, Colman-Lerner, Court, Crampin, Cvrckova, Dong, Drgonova, Dunkler, Feng, Finger, France, Gao, Girbardt, Gladfelter, Goehring, Gorovits, Gulli, Guo, Harris, Harris, Hartwell, Hergovich, Hou, Hou, Irazoqui, Jin, Karnoub, Knechtle, Kohno, Konzack, Kron, Leberer, Leberer, Leberer, Leonhard, Lew, Li, Liu, Loeb, Loeb, Longtine, Mahlert, Mata, McCollum, McCusker, Medkova, Mehta, Mendenhall, Nelson, Nonaka, Novick, Pan, Park, Pearson, Peter, Peter E. Sudbery, Philippsen, Punt, Qadota, Racki, Read, Santangelo, Schmidt, Seiler, Seiler, Sinha, Smith, Soll, Stevenson, Sudbery, Sudbery, Sudbery, Tamaskovic, Tanaka, Tcheperegine, Trinci, Verde, Versele, Virag, Virag, Walton, Walworth, Wedlich-Soldner, Wedlich-Soldner, Wendland, Wu, Yarden, Zhang, Zheng, Zheng   +112 more
core   +1 more source

Myosin IIA-mediated forces regulate multicellular integrity during vascular sprouting [PDF]

, 2019
Angiogenic sprouting is a critical process involved in vascular network formation within tissues. During sprouting, tip cells and ensuing stalk cells migrate collectively into the extracellular matrix while preserving cell-cell junctions, forming patent ...
Chen, Christopher S., Choi, Colin, Dong, Li, Eyckmans, Jeroen, Howes, Caroline, King, Jessica, Mirabella, Teodelinda, Oberai, Assad, Stapleton, Sarah, Yang, Jinling, Yoon, Christine   +10 more
core   +1 more source

LocalZProjector and DeProj: a toolbox for local 2D projection and accurate morphometrics of large 3D microscopy images

BMC Biology, 2021
Background Quantitative imaging of epithelial tissues requires bioimage analysis tools that are widely applicable and accurate. In the case of imaging 3D tissues, a common preprocessing step consists of projecting the acquired 3D volume on a 2D plane ...
Sébastien Herbert, Léo Valon, Laure Mancini, Nicolas Dray, Paolo Caldarelli, Jérôme Gros, Elric Esposito, Spencer L. Shorte, Laure Bally-Cuif, Nathalie Aulner, Romain Levayer, Jean-Yves Tinevez   +11 more
doaj   +1 more source

Human Intestinal Morphogenesis Controlled by Transepithelial Morphogen Gradient and Flow-Dependent Physical Cues in a Microengineered Gut-on-a-Chip

iScience, 2019
Summary: We leveraged a human gut-on-a-chip (Gut Chip) microdevice that enables independent control of fluid flow and mechanical deformations to explore how physical cues and morphogen gradients influence intestinal morphogenesis.
Woojung Shin, Christopher D. Hinojosa, Donald E. Ingber, Hyun Jung Kim   +3 more
doaj   +1 more source

Brain-specific lipoprotein receptors interact with astrocyte derived apolipoprotein and mediate neuron-glia lipid shuttling

Nature Communications, 2021
Lipophorin receptors (LpRs) regulate structural and functional development of neurons in Drosophila. Here authors demonstrate how short isoforms of LpR1 mediates astrocyte lipid shuttling to neuron through interacting with glia lipoprotein GLaz and the ...
Jun Yin, Emma Spillman, Ethan S. Cheng, Jacob Short, Yang Chen, Jingce Lei, Mary Gibbs, Justin S. Rosenthal, Chengyu Sheng, Yuki X. Chen, Kelly Veerasammy, Tenzin Choetso, Rinat Abzalimov, Bei Wang, Chun Han, Ye He, Quan Yuan   +16 more
doaj   +1 more source

Evidence of a possible multicellular life cycle in Escherichia coli

iScience, 2023
Summary: Biofilms are surface-attached multicellular microbial communities. Their genetics have been extensively studied, but the cell-scale morphogenetic events of their formation are largely unknown.
Devina Puri, Xin Fang, Kyle R. Allison
doaj   +1 more source

A Multifunctional 3D Co-Culture System for Studies of Mammary Tissue Morphogenesis and Stem Cell Biology

PLoS ONE, 2011
Studies on the stem cell niche and the efficacy of cancer therapeutics require complex multicellular structures and interactions between different cell types and extracellular matrix (ECM) in three dimensional (3D) space. We have engineered a 3D in vitro model of mammary gland that encompasses a defined, porous collagen/hyaluronic acid (HA) scaffold ...
Jonathan J Campbell, Natalia Davidenko, Maria M Caffarel, Ruth E Cameron, Christine J Watson   +4 more
openaire   +4 more sources

A multi-protein receptor-ligand complex underlies combinatorial dendrite guidance choices in C. elegans. [PDF]

, 2016
Ligand receptor interactions instruct axon guidance during development. How dendrites are guided to specific targets is less understood. The C. elegans PVD sensory neuron innervates muscle-skin interface with its elaborate dendritic branches.
Dong, Xintong, Shen, Ao, Shen, Kang, Tugizova, Madina, Xiang, Yang K, Zou, Wei   +5 more
core   +2 more sources

Continuous and intermittent exposure of neonatal rat calvarial cells to PTHrP (1-36) inhibits bone nodule mineralization in vitro by downregulating bone sialoprotein expression via the cAMP signaling pathway [v2; ref status: indexed, http://f1000r.es/18x]

F1000Research, 2013
The development and growth of the skeleton in the absence of parathyroid-hormone-related protein (PTHrP) is abnormal.  The shortening of appendicular bones in PTHrP gene null mice is explained by an effect of PTHrP on endochondral bone growth.
Suzan A Kamel, John A Yee
doaj   +1 more source