Results 21 to 30 of about 174,983 (236)
PLoS ONE, 2011 Studies on the stem cell niche and the efficacy of cancer therapeutics require complex multicellular structures and interactions between different cell types and extracellular matrix (ECM) in three dimensional (3D) space. We have engineered a 3D in vitro model of mammary gland that encompasses a defined, porous collagen/hyaluronic acid (HA) scaffold ...
Jonathan J Campbell +4 more
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F1000Research, 2013 The development and growth of the skeleton in the absence of parathyroid-hormone-related protein (PTHrP) is abnormal. The shortening of appendicular bones in PTHrP gene null mice is explained by an effect of PTHrP on endochondral bone growth.
Suzan A Kamel, John A Yee
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Transcriptional regulation of endothelial cell behavior during sprouting angiogenesis
Nature Communications, 2017 Angiogenesis is a complex process that requires coordinated changes in endothelial cell behavior. Here the authors use Ribo-tag and RNA-Seq to determine temporal profiles of transcriptional activity during postnatal retinal angiogenesis, identifying ...
Hyun-Woo Jeong +9 more
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Unified quantitative characterization of epithelial tissue development
eLife, 2015 Understanding the mechanisms regulating development requires a quantitative characterization of cell divisions, rearrangements, cell size and shape changes, and apoptoses.
Boris Guirao +8 more
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Cell ReportsSummary: Choanoflagellates, the closest living relatives of animals, provide crucial insights into animal origins. The multicellular choanoflagellate Salpingoeca rosetta can be genetically modified, but existing knockout (KO) pipelines are time consuming
Chantal Combredet +2 more
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Comparative transcriptome analyses of the Drosophila pupal eye
G3: Genes, Genomes, Genetics, 2020 Tissue function is dependent on correct cellular organization and behavior. As a result, the identification and study of genes that contribute to tissue morphogenesis is of paramount importance to the fields of cell and developmental biology. Many of the
Miles W DeAngelis +2 more
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Live imaging of echinoderm embryos to illuminate evo-devo
Frontiers in Cell and Developmental Biology, 2022 Echinoderm embryos have been model systems for cell and developmental biology for over 150 years, in good part because of their optical clarity. Discoveries that shaped our understanding of fertilization, cell division and cell differentiation were only ...
Vanessa Barone, Deirdre C. Lyons
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The kinase regulator mob1 acts as a patterning protein for stentor morphogenesis. [PDF]
PLoS Biology, 2014 Morphogenesis and pattern formation are vital processes in any organism, whether unicellular or multicellular. But in contrast to the developmental biology of plants and animals, the principles of morphogenesis and pattern formation in single cells ...
Mark M Slabodnick +5 more
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Various scenarios of the cell pattern formation in Arabidopsis lateral root
Acta Societatis Botanicorum Poloniae, 2014 During lateral root (LR) development a coordinate sequence of cell divisions, accompanied by a change of the organ form takes place. Both the order of anatomical events and morphological features may vary for individual primordia.
Jolanta Białek +2 more
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Cell Differentiation and Replication during Postnatal Development of the Murine First Molar
Biology, 2021 Various signaling molecular pathways are involved in odontogenesis to promote cellular replication and differentiation. Tooth formation is controlled mainly by epithelial–mesenchymal interactions.
Rudi Balzano +2 more
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