Results 131 to 140 of about 21,395 (260)

Mechanochemical Strategies Applied to the Late‐Stage Modifications of Pharmaceutically Active Compounds

Angewandte Chemie International Edition, Volume 64, Issue 41, October 6, 2025.
This review highlights mechanochemical strategies for the late‐stage modification of active pharmaceutical ingredients (APIs), providing a valuable resource for selecting substrates to evaluate the pharmaceutical potential of novel and existing (mechano)chemical protocols.
Johanna Templ, Lars Borchardt
wiley   +1 more source

Efficient Synthesis of Acylsilanes Using Morpholine Amides. [PDF]

, 2005
Christopher T. Clark, Benjamin C. Milgram, Karl A. Scheidt   +2 more
openalex   +1 more source

Enantiocomplementary Bioreduction of Flexible Ring N‐(3‐Oxobutyl)Heterocycles Providing Enantiopure Chiral Fragments for Drug Discovery

ChemBioChem, Volume 26, Issue 19, October 3, 2025.
Bioreduction of flexible ring N‐(3‐oxobutyl)‐heterocycles mediated by enantiocomplementary recombinant alcohol dehydrogenases [an (S)‐selective one from Rhodococcus aetherivorans (RaADH), and an (R)‐selective one from Lactobacillus kefir (LkADH)], as whole‐cell biocatalysts results in enantiopure (S)‐ and (R)‐alcohols (ee > 99%), which are promising ...
Máté Gergő Honvári, Levente András Mócza, Bence Attila Kucsinka, Pál Csuka, Viktória Bódai, Diana Maria Scrob, László Poppe, Gábor Hornyánszky   +7 more
wiley   +1 more source

The Study of the Reaction of Morpholine with 4-Bromobenzaldehyde in the Presence and Absence of Copper(I) Iodide

, 1970
Dorairaaj Sivasubramaniam, Meng Guan Tay
openalex   +2 more sources

Characterization of the thermophilic xylanase Fsa02490Xyn from the hyperthermophile Fervidibacter sacchari belonging to glycoside hydrolase family 10

FEBS Open Bio, Volume 15, Issue 10, Page 1629-1642, October 2025.
Fervidibacter sacchari is a member of the bacterial phylum Armatimonadota, only a few of which have been cultivated. It is a hyperthermophilic polysaccharide degradation specialist. We show that a secreted enzyme, Fsa02490Xyn, is an endoxylanase belonging to glycoside hydrolase family 10.
Nicole Torosian, Jonathan K. Covington, Allison M. Cook, Nancy O. Nou, Marike Palmer, Ritesh Mewalal, Miranda Harmon‐Smith, Ian K. Blaby, Jan‐Fang Cheng, Matthias Hess, Brian P. Hedlund   +10 more
wiley   +1 more source

4-(Benzoylthiocarbonyl)morpholine

Acta Crystallographica Section E Structure Reports Online, 2005
Wei-Wei Liu, Yi-Zhi Li, Hongwen Hu, Ling-Dong Kong   +3 more
openaire   +2 more sources

Synthesis and Evaluation of Benzophenone-N-ethyl Morpholine Ethers as Anti-inflammatory Agents [PDF]

, 2010
Shaukath Ara Khanum, Bushra A Begum, Noor Fatima Khanum, V. Girish   +3 more
openalex   +1 more source

SYNTHESIS AND CHARACTERIZATION OF SOME NOVEL THIAZOLE, THIAZOLO[3,2-A]PYRIDINE AND THIAZOLO[3,2-A]-1,8-NAPHTHYRIDINE DERIVATIVES CONTAINING MORPHOLINE MOIETY [PDF]

, 2010
Gameel A. M. Elhagali
openalex   +1 more source

Synthesis and Biological Evaluation of Novel 2‐(Piperidin‐4‐yl)‐1,2,3,4‐tetrahydroisoquinoline and 2‐(Piperidin‐4‐yl)decahydroisoquinoline Antimycotics

Archiv der Pharmazie, Volume 358, Issue 10, October 2025.
A series of 13 hybrid molecules of both lead structures were prepared using reductive amination as key reaction step. The antimycotic potency of the resulting compounds was evaluated against yeast and mold species. Two compounds showed remarkable potency against several yeasts, and even against Candida krusei.
Marie‐Christin Hain, Monika Klimt, Franz Bracher, Ulrike Binder, Jürgen Krauß   +4 more
wiley   +1 more source

(2R*,6S*)-tert-Butyl 2,6-bis(hydroxymethyl)morpholine-4-carboxylate [PDF]

, 2010
Qian Chen, Bojun Li, Guangxin Xia
openalex   +1 more source