Results 131 to 140 of about 18,579 (227)

Stereodivergent Synthesis of C5‐α‐Substituted Linezolid Derivatives From D‐Mannitol and Structure–Antibacterial Activity Evaluation

open access: yesChirality, Volume 38, Issue 9, September 2026.
A stereodivergent route from D‐mannitol enables access to enantiopure C5‐α‐substituted linezolid analogues with full configurational control. Biological evaluation reveals that α‐substitution abolishes antibacterial activity irrespective of stereochemistry, establishing a strict steric limitation at C5 and highlighting the dominant role of substituent ...
José A. Gálvez   +3 more
wiley   +1 more source

Stereoselective and Diastereospecific Aminosilylation and Hydrosilylation of Heterobicyclic Alkenes by Copper Catalysis Under Mild Conditions

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 33, 1 September 2026.
An efficient and straightforward methodology for the stereoselective and diastereospecific aminosilylation and hydrosilylation of heterobicyclic norbornene derivatives is introduced. The mild conditions enable the functionalization of norbornene substrates with broad functional‐group tolerance.
Daniel Kamzol   +3 more
wiley   +1 more source

Fostamatinib Dual Immunomodulation in Post-Haploidentical HSCT Autoimmune Cytopenia and Autoimmune Hepatitis: A Case Report and Review of Literature. [PDF]

open access: yesJ Clin Immunol
Tessitore A   +7 more
europepmc   +1 more source

A Perspective of Soy Isoflavones on Analytical, Biological, and Chemical Attributes

open access: yesLegume Science, Volume 8, Issue 3, September 2026.
ABSTRACT This review covers key aspects of soybean (Glycine max), with a particular focus on its isoflavone content and biological properties. Soybeans maintain their position as both a nutraceutical and a pharmaceutical crop, with a broad range of dietary items used worldwide, including soy milk, fermented soy products, and various dietary supplements.
Sristy Suman   +4 more
wiley   +1 more source

Aprepitant and Fosaprepitant for Preventing Nausea and Vomiting in Patients Receiving Highly Emetogenic Chemotherapy-A Real-World Study. [PDF]

open access: yesCurr Oncol
Ünlü B   +8 more
europepmc   +1 more source

SMILES2Docking: An Open‐Source Desktop Workflow for Ligand Ionization, Stereochemistry‐Aware Preparation and Semi‐Empirical 3D Refinement

open access: yesMolecular Informatics, Volume 45, Issue 9, September 2026.
SMILES2Docking is an open‐source desktop workflow that converts spreadsheet SMILES libraries into docking‐ready 3D ligands. A single auditable pipeline performs structural curation, stereochemistry control, MolGpKa pH‐dependent ionization, molecular mechanics geometry, and optional semi‐empirical MOPAC refinement, and exports MOL2, SDF, or PDBQT files.
Daniel Andrés Grajales Ruiz   +4 more
wiley   +1 more source

Response Surface Method‐Optimized Microwave‐Assisted Extraction and LC–MS/MS Profiling of Bioactive Compounds Wild Edible Arisaema schimperianum Tuber

open access: yesSEPARATION SCIENCE PLUS, Volume 9, Issue 9, September 2026.
Response surface optimization identified 60% microwave power and 40 s as a balanced condition for recovering bioactive compounds from Arisaema schimperianum tuber. LC–MS/MS profiling revealed diverse metabolites, while freeze‐drying best preserved thermolabile compounds, highlighting an effective strategy for maximizing extraction efficiency and ...
Gezahegn Abawa Zeleke   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy