Results 61 to 70 of about 27,788 (185)
Zeitschrift für Naturforschung B, 1972 A new synthesis has been developed for the hitherto unreported 2-substituted-3-oxo-4H-1,4-oxazines 3b-3j via the cyclodehydrohalogenation of N-aryl-N-dichloroacetyl-2-amino-4′-nitroacetophenones in dimethyl sulfoxide with potassium t-butoxide. The structures of all the oxazine derivatives have been verified by IR and NMR spectroscopy and correlations ...
openaire +1 more source
Health Benefits of Polysaccharides in Red Algae: A Comprehensive Review
Food Frontiers, Volume 7, Issue 2, March 2026.Graphical abstract showing the health benefits of red algal polysaccharides. ABSTRACT Humans have long consumed red algae (especially by the Asian community), and their polysaccharide extracts (carrageenan, agar) are extensively used in the food industry as gel thickeners.
Sammueal Jun Kai Ong +10 more
wiley +1 more source
Medicinal Research Reviews, Volume 46, Issue 2, Page 352-381, March 2026.ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi +2 more
wiley +1 more source
Magnetic Resonance in Chemistry, Volume 64, Issue 3, Page 324-332, March 2026.We report the results from a kinetic and mechanistic investigation of an inverse‐electron‐demand Diels–Alder (IEDDA) cycloaddition involving an oxazole‐type diene synthesized via an Ugi–Zhu multicomponent reaction (UZ‐3CR). ABSTRACT Pyridines are a crucial class of heterocycles with widespread applications in natural products, pharmaceuticals, and ...
Galdina V. Suárez‐Moreno +6 more
wiley +1 more source
Turn‐Induction in Peptides Incorporating Novel Cyrene‐Derived α,α‐Disubstituted Amino Acid
Journal of Peptide Science, Volume 32, Issue 3, March 2026.Novel chiral cyrene‐derived Cyr residues were incorporated into peptides. The α,α‐disubstituted amino acid residue was introduced using the Ugi reaction. X‐ray crystallographic analysis of R‐ and S‐Cyr residues indicated preference to adopt left‐ and right‐handed α‐helical conformations, respectively.
Kajumee Bora Bhowal +2 more
wiley +1 more source
Cytotoxicity and Antimicrobial Activity of GaMF1 Analogs
ChemMedChem, Volume 21, Issue 4, 25 February 2026.GaMF1 is a reported, highly potent inhibitor of mycobacterial ATP synthase. Structural modification of this scaffold significantly changes biological activity. We present GaMF1 analogues with strong antiparasitic effects, potential antiproliferative properties, and discuss the selectivity limitations of the parent compound and its analogues.
Jan Chasák +8 more
wiley +1 more source
ChemMedChem, Volume 21, Issue 4, 25 February 2026.A high‐throughput cellular screen based on Ca2+ influx in U937 monocytic cells identified thiadiazoles as small‐molecule inhibitors of α‐hemolysin, a key virulence factor of Staphylococcus aureus. The thiadiazole 1 prevents pore formation by a dual mechanism that prevents stem loop unfolding as well as membrane attachment.
Vadim S. Korotkov +9 more
wiley +1 more source
European Journal of Organic Chemistry, Volume 29, Issue 6, 13 February 2026.An ATRA‐based, Ru‐photocatalyzed radical‐polar crossover reaction for the preparation of monoprotected dicarbonyl compounds is reported. This procedure is based on the capture of a cationic intermediate, arising from the radical step, with diverse nucleophiles.
Derek Mota‐Hernández +2 more
wiley +1 more source
Heterocyclic Merging of Stereochemically Diverse Chiral Piperazines and Morpholines with Indazoles. [PDF]
Chemistry, 2023 Viveki AB +6 more
europepmc +1 more source
Genomic Surveillance and Molecular Evolution of Fungicide Resistance in European Populations of Wheat Powdery Mildew. [PDF]
Mol Plant PatholMinadakis N +6 more
europepmc +2 more sources