Results 121 to 130 of about 4,012,050 (346)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Descriptive macroscopic anatomy of the central nervous system six-banded armadillo (Euphractus sexcintus, Linnaeus, 1758) and nine-banded armadillo (Dasypus novemcinctus, Linnaeus, 1758)

Jornal Interdisciplinar de Biociências, 2016
Armadillos of the species Dasypus novemcinctus and Euphractus sexcintus are xenarthrico is a mammal that inhabits fields and has several eating habits.
João Victor Silva Araújo, Maria Michele Araújo de Sousa Cavalcante, Paulo César de Jesus Gonçalves, Sérgio Paulo Lima Guerra, Andrezza Braga Soares da Silva, Airton Mendes Conde Júnior   +5 more
doaj  

The roof and lateral recesses of the fourth ventricle, considered morphologically and embryologically [PDF]

, 1900
Joseph A. Blake
openalex   +1 more source

Astrocyte morphology

Trends in Cell Biology
Astrocytes are predominant glial cells that tile the central nervous system (CNS). A cardinal feature of astrocytes is their complex and visually enchanting morphology, referred to as bushy, spongy, and star-like. A central precept of this review is that such complex morphological shapes evolved to allow astrocytes to contact and signal with diverse ...
Baldwin, Katherine T, Murai, Keith K, Khakh, Baljit S   +2 more
openaire   +4 more sources

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Death Risk Score Model of Hospitalized COVID-19 Patients: A Cohort Study

International Journal of Clinical Practice
Conclusion: The routine laboratory on hospital admission may be a good predictor of mortality during the hospitalization follow-up of COVID-19 patients. A score risk may be adjusted and calculated based on these markers.
Gustavo A. Cruz, Thais B. Boteon, Henrique Pott, Sigrid de Sousa dos Santos, Bruna Dias de Lima Fragelli, Cynthia Aparecida de Castro, Joice Margareth de Almeida Rodolpho, Davi Casale Aragon, Fernanda de F. Anibal, Meliza Goi Roscani   +9 more
doaj   +1 more source

Morphology of the nervous system of cypris [PDF]

, 1896
C. H. Turner
openalex   +1 more source

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

FEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel, Rachel Brown, Alexa Rabeling, Mubeen Goolam   +3 more
wiley   +1 more source

Correlation between the region of interest in digital radiography, Hounsfield units, and histological maturation on Wistar rats submitted to tibial fracture

Journal of the Foot & Ankle
Objective: Study the relationship between the region of interest (ROI) and Hounsfield units (HU) in the tibial bone callus. Methods: Twenty-one adult Wistar rats were submitted to tibial fracture.
Eduardo de Oliveira Carrilho Padula, Lucas Pires, Marcio Babinski   +2 more
doaj   +1 more source