Results 71 to 80 of about 1,103,016 (356)

Data incongruence and the problem of avian louse phylogeny [PDF]

, 2004
Recent studies based on different types of data (i.e. morphological and molecular) have supported conflicting phylogenies for the genera of avian feather lice (Ischnocera: Phthiraptera).
Archie J. W., Bandelt H.-J., Blagoveshtchenskii D. I., Bremer K., Choe J. C., Clay T., Clayton D. H., Clayton D. H., Corpet F., Cunningham C. W., Danforth B. N., Darlu P., Eichler W. D., Emerson K. C., Estabrook G. F., Faith D. P., Felsenstein J., Hafner M. S., Hafner M. S., Hillis D. M., Hillis D. M., Hopkins G. H. E., Huelsenbeck J. P., Johnson K. P., Johnson K. P., Jow H., Kallersjo M., Kellogg V. L., Kluge A. G., Konigsmann E., Lockhart P. J., Lockhart P. J., Lopez P., Loye J. E., Lyal C. H. C., Maddison W. P., Meacham C. A., Mey E., Mey E., Page R. D. M., Page R. D. M., Page R. D. M., Palma R. L., Price R. D., Rambaut A., Reed D. L., Rozsa L., Rzhetsky A., Simon C., Swofford D. L., Wheeler W. C., Wilkinson M., Zharkikh A.   +52 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Comparative Analysis Of Zebrafish And Planarian Model Systems For Developmental Neurotoxicity Screens Using An 87-Compound Library [PDF]

, 2019
There is a clear need to establish and validate new methodologies to more quickly and efficiently screen chemicals for potential toxic effects, particularly on development. The emergence of alternative animal systems for rapid toxicology screens presents
Collins, Eva-Maria S., Hagstrom, D., Tanguay, R., Truong, L., Zhang, S.   +4 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

An Overview of Immunotherapeutic Approaches Against Canine Visceral Leishmaniasis: What Has Been Tested on Dogs and a New Perspective on Improving Treatment Efficacy

Frontiers in Cellular and Infection Microbiology, 2019
Visceral leishmaniasis (VL), caused by digenetic protozoa of the genus Leishmania, is the most severe form of leishmaniasis. Leishmania infantum is one of the species responsible for VL and the disease caused is considered a zoonosis whose main reservoir
Ana Alice Maia Gonçalves, Jaqueline Costa Leite, Lucilene Aparecida Resende, Reysla Maria da Silveira Mariano, Patricia Silveira, Otoni Alves de Oliveira Melo-Júnior, Helen Silva Ribeiro, Diana Souza de Oliveira, Diogo Fonseca Soares, Thaiza Aline Pereira Santos, Alexandre Ferreira Marques, Alexsandro Sobreira Galdino, Olindo Assis Martins-Filho, Walderez Ornelas Dutra, Denise da Silveira-Lemos, Rodolfo Cordeiro Giunchetti   +15 more
doaj   +1 more source

Crinoid phylogeny: a preliminary analysis (Echinodermata: Crinoidea) [PDF]

, 2004
We describe the first molecular and morphological analysis of extant crinoid high-level inter-relationships. Nuclear and mitochondrial gene sequences and a cladistically coded matrix of 30 morphological characters are presented, and analysed by ...
Ameziane, N., Cohen, B.L., De Forges, B.R., Eleaume, M.   +3 more
core   +3 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

THE ART OF WAR: PATTERNS AND MECHANISMS UNDERLYING PREDATOR-INDUCED PLASTICITY OF AMPHIBIANS [PDF]

, 2013
Organisms often employ phenotypic plasticity as a strategy to cope with variable environments. This is particularly true of predation threats, wherein prey induce defenses to reduce detection or capture by predators.
Relyea, Rick A, Shaffery, Heather M
core  

Using step width to compare locomotor biomechanics between extinct, non-avian theropod dinosaurs and modern obligate bipeds [PDF]

, 2017
How extinct, non-avian theropod dinosaurs locomoted is a subject of considerable interest, as is the manner in which it evolved on the line leading to birds. Fossil footprints provide the most direct evidence for answering these questions. In this study,
Barrett, R S, Bishop, P J, Clemente, C J, Graham, D F, Hocknull, S A, Hutchinson, J R, Lamas, L P, Lloyd, D G, Rubenson, J, Weems, R E, Wilson, R S   +10 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source