Results 71 to 80 of about 49,566 (282)

Evaluación morfométrica y genética de la estructura poblacional de Cynoscion guatucupa de la costa de Buenos Aires en el Mar Argentino [PDF]

, 2010
This study analyzed the morphometric, microsatellite loci and mitochondrial control region variation of the striped weakfish from two feeding and spawning grounds in the coastal area of Buenos Aires province. The characterization of the body shape proved
Díaz de Astarloa, Clara María, Fernández Iriarte, Pedro J., González Castro, Mariano, Iudica, Celia Estela, Sabadin, David Ezequiel   +4 more
core   +1 more source

The Osteoblastic Microenvironment Determines the Fate of Breast Cancer Cells Disseminated in the Bone Marrow

Advanced Science, EarlyView.
This study revealed how the osteoblastic microenvironment determines the fate of cancer cells disseminated in bone, with a focus on whether they colonize, reside in quiescence, or reactivate from dormancy. Targeting integrin signaling may offer promising strategies for preventing quiescent cancer cells reactivation and bone colonization.
Hong‐Li Wang, Rui Zhang, Xiao‐Min Yue, Jie Zhou, Yu‐Fan Huang, Rong Meng, Yu‐Li Wang, Xiao‐Qing Li   +7 more
wiley   +1 more source

Biodegradable Carbonate Nanogels Loaded with Anti MFAP‐5 siRNA for Anti‐stromal Therapy of Hepatocellular Carcinoma

Advanced Science, EarlyView.
Polycarbonate nanogels enable lipid‐free delivery of anti‐MFAP‐5 siRNA into cancer‐associated fibroblasts (CAF) in hepatocellular carcinoma. In a cirrhotic murine model, this approach silences MFAP‐5, reduces fibroblast activation, and suppresses tumor growth by inhibiting NOTCH/Hes1‐driven angiogenesis. CAF‐targeted MFAP‐5 RNAi and conserved signaling
Paul Schneider, Alexander Fuchs, Michael Fichter, Vanessa Bolduan, Jenny Schunke, Özlem Akilli, Nádia C. Correia, Yannick Ehlers, Christian Czysch, Pia Winterwerber, Eliana Stanganello, Barbara Schrörs, Mustafa Diken, Christoph Eckert, Shusruto Rishik, Andreas Keller, Jörn M. Schattenberg, Stephan Grabbe, Matthias Bros, Lutz Nuhn, Leonard Kaps   +20 more
wiley   +1 more source

Gαi1/3 Is a Novel Regulatory Target for RANKL Signal Transduction and Osteoporosis

Advanced Science, EarlyView.
ABSTRACT Osteoporosis, characterized by progressive bone loss and increased fracture risk, is a growing concern as the population ages. Current treatments, though advanced, remain limited, underscoring the necessity for novel therapeutic targets. Recent studies have shown that the immune system plays a key role in osteoporosis, with osteoclasts driving
Chaowen Bai, Mingchao Zhang, Le Liu, Lide Tao, Chenyang Xu, Hao Chai, Xin Shi, Yin Wang, Xiaopei Zhang, Qiong Chen, Dong Liu, Jinyu Bai, Chang She, Xiaozhong Zhou, Cong Cao, Huajian Shan   +15 more
wiley   +1 more source

Structure and morphometrics of Ancyrocephalus paradoxus (Monogenea: Ancyrocephalidae) from Sander lucioperca (Percidae) in Czechia

Helminthologia, 2019
New morphometric data, including details of the copulatory system and attachment structures, as well as inner organs are provided for Ancyrocephalus paradoxus Creplin, 1839. Scanning electron microscopy reveals new information of the body shape, position
Rubtsova N. Yu., Heckmann R. A.
doaj   +1 more source

Anti‐Apoptotic and Neurite‐Protective Nanomedicine Augments Embryonic Stem Cells‐Derived Retinal Ganglion Cell Transplantation in Glaucoma Recovery

Advanced Science, EarlyView.
Lithium‐epigallocatechin gallate nanoparticles (Li‐EGCG NPs) are co‐transplanted with embryonic stem cell‐derived retinal ganglion cells (ESC‐RGCs) to enhance cell survival and therapeutic efficacy in an acute pathological glaucomatous injury model. This synergistic approach protects RGC cells, preserves retinal structure and improves visual function ...
Moxin Chen, Xiaoyan Jiang, Yuanhui Wang, Zhaobin Luo, Yu Zhang, Siwei Liu, Rui Huang, Dandan Zhang, Zhimin Tang, Yahan Ju, Shaohui Pan, Ni Ni, Wei Feng, Yu Chen, Ping Gu   +14 more
wiley   +1 more source

Approaching a population‐level assessment of body size in pinnipeds using drones, an early warning of environmental degradation

Remote Sensing in Ecology and Conservation
Body mass is a fundamental indicator of animal health closely linked to survival and reproductive success. Systematic assessment of body mass for a large proportion of a population can allow early detection of changes likely to impact population growth ...
Daire Carroll, Eduardo Infantes, Eva V. Pagan, Karin C. Harding   +3 more
doaj   +1 more source

Long-term impacts of captivity on skull morphology and endocranial volume in a marsupial carnivore

Royal Society Open Science
A challenge in modern conservation is maintaining ecological roles and natural behaviours of wildlife in an anthropogenic world. Captive breeding has been linked to morphological changes that may impact individual fitness for reintroduction to the wild ...
Emily L. Scicluna, Marissa L. Parrott, Leila Siciliano-Martina, Margot Michaud, Kylie Robert, Peter T. Green   +5 more
doaj   +1 more source

Isometry in mesosaurs: Implications for growth patterns in early amniotes

Acta Palaeontologica Polonica, 2022
Mesosaurs were small amphibious tetrapods that lived in western Gondwana during the early Permian or even earlier, when temperate Carboniferous–Permian conditions initiated after the glaciations that affected the southern region of Pangea.
PABLO NÚÑEZ DEMARCO, JORGE FERIGOLO, GRACIELA PIÑEIRO   +2 more
doaj   +1 more source

Digital reconstruction of the Ceprano calvarium (Italy), and implications for its interpretation [PDF]

, 2017
The Ceprano calvarium was discovered in fragments on March 1994 near the town of Ceprano in southern Latium (Italy), embedded in Middle Pleistocene layers. After reconstruction, its morphological features suggests that the specimen belongs to an archaic
Benazzi, Stefano, Bernardini, Federico, Biddittu, Italo, Cerroni, Vittorio, Di Vincenzo, Fabio, Dreossi, Diego, Manzi, Giorgio, Profico, Antonio, Rubini, Mauro, Schlager, Stefan, Tuniz, Claudio, Zaio, Paola   +11 more
core   +2 more sources