Health and economic benefits of building ventilation interventions for reducing indoor PM2.5 exposure from both indoor and outdoor origins in urban Beijing, China [PDF]
China is confronted with serious PM2.5 pollution, especially in the capital city of Beijing. Exposure to PM2.5 could lead to various negative health impacts including premature mortality. As people spend most of their time indoors, the indoor exposure to
Lin, Yaoyu +4 more
core +1 more source
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
An application of MCMC simulation in mortality projection for populations with limited data
Objective: IIn this paper, we investigate the use of Bayesian modeling and Markov chain Monte Carlo (MCMC) simulation, via the software WinBUGS, to project future mortality for populations with limited data. In particular, we adapt some extensions of the
Jackie Li
doaj +1 more source
Multipopulation mortality modelling and forecasting: the weighted multivariate functional principal component approaches. [PDF]
Lam KK, Wang B.
europepmc +1 more source
Lee Carter mortality forecasting: application to the Italian population [PDF]
In this paper we investigate the feasibility of using the Lee-Carter methodology to construct mortality forecasts for the Italian population. We fit the model to the matrix of Italian death rates for each gender from 1950 to 2000. A time-varying index of
Haberman, S., Russolillo, M.
core
Childhood mortality in sub-Saharan Africa : cross-sectional insight into small-scale geographical inequalities from Census data [PDF]
Objectives To estimate and quantify childhood mortality, its spatial correlates and the impact of potential correlates using recent census data from three sub-Saharan African countries (Rwanda, Senegal and Uganda), where evidence is lacking.
Clarke, Aileen +2 more
core +1 more source
Molecular cancer prevention: Intercepting disease
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Here we present and discuss the R package modTempEff including a set of functions aimed at modelling temperature effects on mortality with time series data.
Vito M. R. Muggeo
doaj
Estimating under-recognized COVID-19 deaths, United States, march 2020-may 2021 using an excess mortality modelling approach. [PDF]
Iuliano AD +9 more
europepmc +1 more source
Mechanistic modelling of animal dispersal offers new insights into range expansion dynamics across fragmented landscapes [PDF]
Peer ...
Bocedi, Greta +3 more
core +2 more sources

