Results 241 to 250 of about 3,071,110 (344)

Targeting m6A Reader YTHDF1 Enhances Antitumor Immunity and Potentiates Anti‐PD‐L1 Efficacy in Intrahepatic Cholangiocarcinoma

Advanced Science, EarlyView.
The m6A reader YTHDF1 drives intrahepatic cholangiocarcinoma (ICC) progression by remodeling the tumor immune microenvironment. YTHDF1 promotes MDSC recruitment via activation of m6A‐FOSL2‐CXCL6/CXCR2 axis, thereby suppressing CD8+ T cell infiltration and function.
Li Luo, Ziqin Liu, Zimin Song, Dong Zhang, Cong Liang, Fei Fang, Kai Lei, Lina Wang, Weikang Chen, Shunli Shen, Ming Kuang, Xiaoxing Li, Jun Yu, Shiyan Wang, Lixia Xu   +14 more
wiley   +1 more source

Temporal trends and projections in the global burden of congenital genitourinary anomalies from 1990 to 2021: A cross-sectional study. [PDF]

J Int Med Res
Xu S, Zhu H, Shen C, Zheng B, Zhang W.
europepmc   +1 more source

Trends in Causes of Death in Low-Mortality Countries: Implications for Mortality Projections

, 2014
J. Bongaarts
semanticscholar   +1 more source

A tool for projecting age patterns based on a standard age schedule and assumptions on relative risks using linear splines: topals [PDF]

, 2007
Beer, J. de, Gaag, N. van der, Willekens, F.J.   +2 more
core   +2 more sources

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Epidemiological Trends and Projections of PM₂.₅-Attributable COPD Burden in China Over 1990-2035. [PDF]

Int J Chron Obstruct Pulmon Dis
Li M, Wang L, Amhare AF, Song Y, Wan P, Shi S, Qiao L, Guo Y.   +7 more
europepmc   +1 more source

An Implantable Scaffold Sequentially Releasing STING Agonist and B7‐H3 Antibody for Bone Metastasis Immunotherapy

Advanced Science, EarlyView.
We developed an implantable dual‐drug depot using GelMA for bone metastasis treatment, co‐delivering MSA‐2 and αB7‐H3‐loaded CaCO3 microparticles. Sustained release from GelMA scaffold enables MSA‐2 to activate STING signaling and enhance T‐cell infiltration and activation, while sequentially released αB7‐H3 blocks MSA‐2‐induced B7‐H3 upregulation ...
Qijun Lin, Hong Xiao, Shuai Fan, Kaimin Cai, Yanteng Xu, Xinwen Wang, Guanhong Chen, Chuandong Lang, Xinsheng Peng, Mingqiang Li, Yuhu Dai   +10 more
wiley   +1 more source

A Delphi-Based Exploratory Estimation of the Economic Impact of Coccidiosis in Turkish Broiler Production. [PDF]

Animals (Basel)
Tuncel S, Ayvazoğlu PD, Parlatır Y.
europepmc   +1 more source

Leveraging Macrophage Metabolic Reprogramming for Enhanced Anti‐Tumor Immunity

Advanced Science, EarlyView.
Tumor‐associated macrophages (TAMs) are key regulators of the tumor microenvironment (TME), with their metabolic states playing a critical role in tumor progression or regression. This review summarizes current understanding of TAM metabolic plasticity alongside cutting‐edge bioengineering innovations, outlining a roadmap for transforming the ...
Zhiyun Liu, Lingyao Zeng, Xulin Gan, Yilin Zhou, Han Shen, Dan Wu, Xin Shou, Minmin Jiang, Liyun Shi   +8 more
wiley   +1 more source

Correction: Trends in mortality of the WHO-recommended diseases for palliative care in the Republic of Korea, 2014-2023. [PDF]

Front Public Health
Kim M, Kim K, Kim W, Nam EJ, Kye SY, Choi JY.   +5 more
europepmc   +1 more source