Results 61 to 70 of about 3,086,327 (347)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Gestational age-adapted oxygen saturation targeting and outcome of extremely low gestational age neonates (ELGANs)

Swiss Medical Weekly, 2015
QUESTIONS UNDER STUDY: Optimal oxygen saturation (SpO2) targets for extremely low gestational age neonates (ELGANs, gestational age [GA]
Anja Hergenhan, Martina Steurer, Thomas M. Berger   +2 more
doaj   +1 more source

Rates of Mortality in West Africa [PDF]

Journal of the Institute of Actuaries, 1897
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openaire   +2 more sources

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

Molecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva, Bernardo Orr, Ana Azeredo, Andreia Brandão, Manuel R. Teixeira, Paula Paulo   +5 more
wiley   +1 more source

Mortality from asthma in the state of S. Paulo, Brazil (1970-1992)

Revista de Saúde Pública, 1995
Mortality from asthma has shown important variations over time in several countries. In Brazil, a mortality study performed in the 60s, covering the cities of S.Paulo and Ribeirão Preto, and other ten cities showed that S.Paulo presented the lowest death
Lotufo Paulo Andrade, Martins Benseñor Isabela Judith, Lolio Cecília Amaro de   +2 more
doaj  

Pancreatic cancer progression and mortality predicted by depression and anxiety: a systematic review and meta-analysis protocol

Frontiers in Psychiatry
Although the relationship between psychological factors and pancreatic cancer outcomes has been widely discussed, controversy remains. We will for the first time systematically summarize the literature to explore the correlation of anxiety and depression
Ruoqi Zhang, Ruoqi Zhang, Jing Wang, Jing Wang, Peitong Zhang, Zheng Zhang, Zheng Zhang, Rui Miao, Rui Miao   +8 more
doaj   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

The Relationship between Insect Resistance and Tree Age of Transgenic Triploid Populus tomentosa Plants

Frontiers in Plant Science, 2018
To explore the stability of insect resistance during the development of transgenic insect-resistant trees, this study investigated how insect resistance changes as transgenic trees age.
Yachao Ren, Yachao Ren, Jun Zhang, Jun Zhang, Guiying Wang, Guiying Wang, Xiaojie Liu, Li Li, Jinmao Wang, Jinmao Wang, Minsheng Yang, Minsheng Yang   +11 more
doaj   +1 more source

Hedging Pure Endowments with Mortality Derivatives [PDF]

, 2010
In recent years, a market for mortality derivatives began developing as a way to handle systematic mortality risk, which is inherent in life insurance and annuity contracts.
Wang, Ting, Young, Virginia R.
core  

Efficacy of Three Insecticides Applied to Bark to Control \u3ci\u3eAgrilus Planipennis\u3c/i\u3e (Coleoptera: Buprestidae) [PDF]

, 2018
Emerald ash borer (EAB), Agrilus planipennis Fairmaire (Coleoptera: Buprestidae), is a serious exotic pest of ash (Fraxinus) trees in North America. In 2003 and 2004, we tested the efficacy of different insecticides sprayed on the bark of cut ash logs ...
Haack, Robert A, Petrice, Toby R
core   +2 more sources