Results 111 to 120 of about 8,729,284 (310)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Risk Factors for Mortality and Mortality Rate of Sumo Wrestlers.

open access: yesNippon Eiseigaku Zasshi (Japanese Journal of Hygiene), 1995
We compared the mortality rate of sumo wrestlers with that of the contemporaneous Japanese male population, and inferred the usefulness of an index for predicting longevity in sumo wrestlers. The standardized mortality ratios (SMR) for sumo wrestlers were very high in each period, and also high for ages from 35 to 74.
HOSHI, Akio, INABA, Yutaka
openaire   +3 more sources

Using spatio-temporal clustering to identify mortality patterns and anthropogenic drivers in the marine otter (Lontra felina) in north-central Chile

open access: yesFrontiers in Marine Science
IntroductionSmall marine carnivores inhabiting fragmented rocky coastlines are increasingly exposed to anthropogenic pressures, yet mortality drivers in these systems remain poorly quantified.MethodsWe analyzed 22 years of carcass records (2003–2024) and
Frederick Toro   +23 more
doaj   +1 more source

Hedging Brevity Risk with Mortality-based Securities [PDF]

open access: yes
In 2003, Swiss Re introduced a mortality-based security designed to hedge excessive mortality changes for its life book of business. The concern was apparently brevity risk, i.e., the risk of premature death. The brevity risk due to a pandemic is similar
MacMinn, Richard, Richter, Andreas
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

The impact of different therapies on invasive pulmonary aspergillosis in patients with severe fever and thrombocytopenia syndrome: a systematic review and meta-analysis

open access: yesFrontiers in Public Health
BackgroundIn recent years, a growing number of studies have reported that patients with severe fever with thrombocytopenia syndrome (SFTS)-associated invasive pulmonary aspergillosis (SAPA) patients exhibit a relatively high incidence and mortality rate.
Feng Hao   +9 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Combined impact of glucose variability and mineral disorders on mortality and severe cardiorenal events in critically ill CKD patients: a multicenter cohort study

open access: yesFrontiers in Medicine
IntroductionElderly critically ill ICU patients with CKD face high mortality. The independent and combined prognostic roles of glycemic variability (Glucose CV) and calcium-phosphate metabolic disorders in this population remain unconfirmed.MethodsThis ...
Yingyun Peng   +4 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Preoperative NLR and INR, and intraoperative cold ischemia time as predictors of short-term mortality risk in paediatric liver transplantation: a LASSO-cox model study

open access: yesAnnals of Medicine
Objectives Liver transplantation (LT) is an effective treatment for end-stage liver disease in children, but precise risk stratification tools for postoperative mortality remain needed.Methods We retrospectively analyzed 383 pediatric LT recipients ...
Quanhai Zhang   +6 more
doaj   +1 more source

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