Results 91 to 100 of about 8,729,284 (310)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Protocol for a systematic review of sarcopenia in older adults with type 2 diabetes mellitus and its association with increased risk of mortality

Frontiers in Medicine
BackgroundSarcopenia and type 2 diabetes mellitus (T2DM) are prevalent health conditions that significantly impact mortality risk, particularly among older adults.
Phatcharaphon Whaikid, Noppawan Piaseu, Noppawan Piaseu, Anita Souza   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

The V-shaped association between the ratio of neutrophil counts to prognostic nutritional index and 30-, 60-, and 90-day mortality in elderly critically ill patients aged 65 and older with sepsis: a retrospective study based on the MIMIC database

Frontiers in Nutrition
ObjectiveTo investigate the association between the ratio of neutrophil counts to prognostic nutritional index (NPNR) and mortality risk in elderly patients with severe sepsis aged 65 and older.MethodsThis retrospective study utilized data from the MIMIC-
Jierui Cai, Yifeng Jin, Jiaqi Lou, Bingqing Xu, Huan Qi, Jie Li   +5 more
doaj   +1 more source

Total plasma carotenoids and mortality in the elderly: results of the Epidemiology of Vascular Ageing (EVA) study [PDF]

, 2008
Carotenoids are pigments found in fruits and vegetables. While high intakes of fruits and vegetables have been found to be associated with lower mortality, our objective is to investigate if total plasma carotenoids, via their antioxidant properties. are
Berr, C, Berr, Claudine, Akbaraly, Tasnime, N., Favier, A, Favier, Alain, Akbaraly, TN, Akbaraly, Tasnime,   +6 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Good Performance of Revised Scoring Systems in Predicting Clinical Outcomes of Aeromonas Bacteremia in the Emergency Department: A Retrospective Observational Study

Diagnostics
Background: Aeromonas species, Gram-negative, non-sporulating, facultative, and anaerobic bacilli, widely distributed in aquatic environments, derive various infections, including bacteremia.
Cheng-Yang Wen, Sung-Yuan Hu, Ming-Shun Hsieh, Shih-Che Huang, Chia-Hui Shen, Yi-Chun Tsai   +5 more
doaj   +1 more source

Willingness to Pay for Mortality Risk Reductions: Does Latency Matter? [PDF]

Using results from two contingent valuation surveys conducted in Canada and the United States, we explore the effect of a latency period on willingness to pay (WTP) for reduced mortality risk using both structural and reduced form approaches.
Simon, Nathalie, Krupnick, Alan, Alberini, Anna, Cooper, Maureen   +3 more
core   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Risk of Mortality Among Adult Females Diagnosed with Traumatic Brain Injury in an Academic Medical System

Neurotrauma Reports
The objective of this retrospective cohort study was to evaluate mortality risk over five years among 6,432 female patients with a health care encounter diagnosis of TBI from hospitals and outpatient clinics within a university health system. We used TBI
Bernadette A. D’Alonzo, Abigail C. Bretzin, Rebecca B. Morse, Silvia P. Canelón, Douglas J. Wiebe, Andrea L.C. Schneider, Mary Regina Boland   +6 more
doaj   +1 more source