Results 81 to 90 of about 2,190,813 (317)

An Immuno-Fragile Profile Is Associated with Mortality Risk in Patients with Chronic Kidney Disease

Biomedicines
Background/Objectives: Patients with chronic kidney disease (CKD) face higher risks of infections, poor vaccine responses, and cardiovascular diseases, leading to increased morbidity and mortality due to immune dysfunction and frailty. This study aims to
Noemí Ceprián, Irene Martínez de Toda, Paula Jara Caro, Claudia Yuste, Gemma Valera-Arévalo, Ignacio González de Pablos, Andrea Figuer, Matilde Alique, Rafael Ramírez, Enrique Morales, Julia Carracedo   +10 more
doaj   +1 more source

Delta and Gamma hedging of mortality and interest rate risk [PDF]

This paper studies the hedging problem of life insurance policies, when the mortality and interest rates are stochastic. We focus primar- ily on stochastic mortality. We represent death arrival as the rst jump time of a doubly stochastic process, i.e.
Elisa Luciano, Luca Regis, Elena Vigna
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Clinical Profiles and Mortality-Associated Risk Factors in Patients with Acute Kidney Injury from Atlixco, Puebla, Mexico

Diagnostics
Background: Acute Kidney Injury (AKI) is characterized by rising morbidity and mortality rates, along with significant financial costs associated with its treatment, positioning it as a priority health challenge.
Nancy K. Zúñiga-Fernández, Pedro A. Gaspar-Mendoza, Lizeth Torres-Pineda, Elizabeth Baez-Baez, Karina Alvarado-Dardón, Karla V. Gutiérrez-de Anda, Jorge Ayón-Aguilar, Rubí Romo-Rodríguez, Rosana Pelayo, Diana Casique-Aguirre   +9 more
doaj   +1 more source

Anthropometry and mortality : a cohort study of rural Bangladeshi women. [PDF]

Many authors suggest that low anthropometric levels are associated with higher mortality risk in adults, In developing countries however there have been few opportunities to test this hypothesis.
Hosegood, Victoria
core   +1 more source

Adverse socioeconomic conditions in childhood and cause specific adult mortality: prospective observational study [PDF]

, 1998
<b>Objective:</b> To investigate the association between social circumstances in childhood and mortality from various causes of death in adulthood. Design: Prospective observational study. Setting: 27 workplaces in the west of Scotland.
Blane, D., C. Hart, D. Blane, Davey Smith, G., Hole, D., Hart, C.L., G. D. Smith, D. Hole   +7 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Associations of urinary enterolignans and risk of overall and cause-specific mortality with or without serum albumin adjustment: a prospective cohort study

Frontiers in Nutrition
BackgroundThe association between enterolignans (the bioavailable metabolites of dietary lignans) including enterolactone (ENL) and enterodiol (END) and long-term risk of mortality remains limited and inconclusive. Involvement of human serum albumin (HSA)
Zisuo Sun, Zisuo Sun, Zisuo Sun, Zisuo Sun, Qing Wang, Tianyi Shen, Jingming Zhu, Hongli Wang, Wanshui Yang, Wanshui Yang, Wanshui Yang, Wanshui Yang, Zhuang Zhang, Qiang Zhou   +13 more
doaj   +1 more source

Rivalry, solidarity, and longevity among siblings: A life course approach to the impact of sibship composition and birth order on later life mortality risk, Antwerp (1846-1920)

Demographic Research, 2014
Background: Family composition and household dynamics, both in early and in later life, influence individual health and longevity. Both positive and negative effects can be expected in terms of sibling size and composition.
Robyn Donrovich, Paul Puschmann, Koen Matthijs   +2 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source