Results 101 to 110 of about 1,865,481 (313)
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
The modal age at death and the shifting mortality hypothesis [PDF]
The modal age at death is used to study the shifting mortality scenario experienced by low mortality countries. The relations of the life table functions at the modal age are analyzed using mortality models.
Vladimir Canudas-Romo
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Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
علوم بهداشتی ایران, 2014 Background and purpose: Mortality Statistics and rates show the development of a country in the world. These statistics are very important for determining the distribution of risk factors of mortality (in age and gender groups, ethnicity and so on) and ...
Jamshid Yazdani +4 more
doaj
Coherent forecasts of mortality with compositional data analysis
Demographic Research, 2017 Background: Mortality trends for subpopulations, e.g., countries in a region or provinces in a country, tend to change similarly over time. However, when forecasting subpopulations independently, the forecast mortality trends often diverge.
Marie-Pier Bergeron-Boucher +3 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Differential mortality by lifetime earnings in Germany [PDF]
e estimate mortality rates by a measure of socio-economic status in a very large sample of male German pensioners aged~65 or older. Our analysis is entirely nonparametric.
Hans-Martin von Gaudecker +1 more
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Frontiers in Veterinary ScienceAggregated diagnostic data collected over time from swine production systems is an important data source to investigate swine productivity and health, especially when combined with records concerning the pre-weaning and post-weaning phases of production.
Edison S. Magalhães +12 more
doaj +1 more source
Gender differences in social mortality differentials in Switzerland (1990-2005) [PDF]
Using data from the 1990 and 2000 Swiss Federal Censuses linked to the death records of the years 1990-1995 and 2000-2005, this paper investigates gender differences in mortality differentials by level of educational achievement and by marital status. In
Reto Schumacher, Sarah Vilpert
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