Results 131 to 140 of about 24,512 (305)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
, 2003 The lateral distribution of the effective contact potential difference (ECPD), often referred to as the work-function difference φMS, was determined experimentally for the first time over the gate area of a metal-oxide-semiconductor (MOS) structure.
Massoud, H. Z. +5 more
core
The application of neuMOS transistors to enhanced Built-in Self-Test (BIST) and product quality [PDF]
, 1999 The neuMOS transistor is a comparatively new device developed in 1991 at Tohoku University, Japan, which is currently showing great promise in the direction of enhanced circuit functionality, particularly in Neural Network applications.
Richardson, Andrew, Nicholson, Richard
core
Photoelectron–grain boundary scattering in al films of MOS structures
, 1978 Internal photoemission is studied in MOS structures by measuring the photocurrents obtained when the metal electrode – a thin Al film – is negatively polarized with respect to the Si slice and photons hv higher than the SiO2–Al interface barrier are ...
GEDDO, MARIO, G. Soncini, A. Stella
core +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Instrumental and technological modeling of autoemission silicon microcathodes
Технологія та конструювання в електронній апаратурі, 2008 A structure of a system for converting topological information for digital lithography is proposed. A method for forming local three-dimensional SOI (Silicon-on-Insulator) structures has been developed, which makes it possible to create both planar and ...
А. A. Druzhynin +4 more
doaj
Reduction of hole traps in GaN MOS structures by high-pressure oxygen annealing [PDF]
Hara Masahiro, Tomigahara Kazuki, Nozaki Mikito, et al. Reduction of hole traps in GaN MOS structures by high-pressure oxygen annealing. Applied Physics Letters 127, 074011 (2025); https://doi.org/10.1063/5.0292841.The impact of annealing pressure on ...
Kobayashi, Takuma +4 more
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
A photodetector based on p-GaN/N-MoS2 QDs heterojunction with high responsivity
Materials Research ExpressMolybdenum disulfide (MoS _2 ) is the most thoroughly investigated for photodetection applications with direct bandgap transition in low-dimensional structures, high light–matter interaction, and good carrier mobility.
Maymunah A Alwehaibi +8 more
doaj +1 more source