Results 121 to 130 of about 943,002 (392)

Autophagy Activators Normalize Aberrant Tau Proteostasis and Rescue Synapses in Human Familial Alzheimer's Disease iPSC‐Derived Cortical Organoids

Advanced Science, EarlyView.
A new cerebrocortical organoid model using isogenic hiPSCs with familial Alzheimer's mutations recapitulates key AD features, including amyloid‐beta and phospho‐Tau aggregation, neuronal hyperexcitability, and synapse loss. Single‐cell RNA‐seq reveals aberrant pathways in excitatory and inhibitory neurons.
Sergio R. Labra, Jadon Compher, Akhil Prabhavalkar, Mireya Almaraz, Claudia Cedeño Kwong, Christine Baal, Maria Talantova, Nima Dolatabadi, Julian Piña‐Sanz, Yubo Wang, Leonard Yoon, Swagata Ghatak, Zi Gao, Yuting Zhang, Dorit Trudler, Lynee Massey, Wei Lin, Anthony Balistreri, Michael Bula, Nicholas J. Schork, Tony S. Mondala, Steven R. Head, Jeffery W. Kelly, Stuart A. Lipton   +23 more
wiley   +1 more source

Comparing MOSAIC and the variational learning model of the optional infinitive stage in early child language [PDF]

, 2009
This paper compares MOSAIC and the Variational Learning Model (VLM) in terms of their ability to explain the level of finiteness marking in early child Dutch, English, Spanish, German and French.
Freudenthal, D, Gobet, F, Pine, J M
core   +1 more source

Determination of the mosaic angle distribution of Grafoil platelets using continuous-wave NMR spectra

, 2009
We described details of a method to estimate with good accuracy the mosaic angle distributions of microcrystallites (platelets) in exfoliated graphite like Grafoil which is commonly used as an adsorption substrate for helium thin films.
B. Cowan, H. Bozler, H. Fukuyama, H. Godfrin, H. Taub, Hiroshi Fukuyama, L.D. Dillon, P. Schiffer, S. Takayoshi, S. Takayoshi, Y. Niimi   +10 more
core   +1 more source

NuSAP Safeguards Centriole Integrity to Mediate CEP57‐CEP152 Torus Recruitment for Proper Engagement

Advanced Science, EarlyView.
This study reveals a novel role for the microtubule stabilizer NuSAP at centrioles. NuSAP depletion destabilizes the centriole's tubulin structure, causing premature disengagement, PCM defects, and mis‐localization of the CEP57‐CEP63‐CEP152 complex. By reinforcing centriole architecture, NuSAP enables early CEP57 loading and initiates a newly proposed ...
Shiyu Zhang, Zemin Jiang, Qiaoyun Yang, Hong Zheng, Minghao Wang, Chennianci Zhu, Lih‐Wen Deng, Karen Carmelina Crasta, Yih‐Cherng Liou   +8 more
wiley   +1 more source

First Report of Costus Stripe Mosaic Virus Infecting Tradescantia spathacea Plants in Brazil

, 2021
Gabriel Madoglio Favara, de Oliveira, Camila Geovana Ferro, Heron Delgado Kraide, Eike Yudi Nishimura Carmo, Gressa Amanda Chinelato, Elliot Watanabe Kitajima, Jorge Alberto Marques Rezende   +7 more
openalex   +1 more source

Reference‐Guided Chromosome‐by‐Chromosome de novo Assembly at Scale Using Low‐Coverage High‐Fidelity Long‐Reads with HiFiCCL

Advanced Science, EarlyView.
HiFiCCL, as the first assembly framework specifically designed for low‐coverage high‐fidelity reads, improves the assembly quality of existing assemblers and also enhances downstream applications such as large structural variant (SV) detection (>10 000 bp), synteny analysis, pangenome graph construction, and graph‐based individual‐specific germline SVs
Zhongjun Jiang, Weihua Pan, Runtian Gao, Heng Hu, Wentao Gao, Murong Zhou, Yu‐Hang Yin, Zhipeng Qian, Shuilin Jin, Guohua Wang   +9 more
wiley   +1 more source

Mikrodontia Insisif Lateral Sebagai Salah Satu Manifestasi Oral Penderita Sindrom Down Tipe Mosaik dan Penuh

Majalah Kedokteran Bandung, 2014
Microdontia is the term when tooth size is smaller than normal, also called conical teeth. Etiology is multifactorial. Microdontia, commonly follow the syndromes. Down syndrome is common followed by microdontia. The aim of this study was to find out oral
Willyanti Syarif
doaj   +1 more source

Mosaic number of knots

, 2014
Lomonaco and Kauffman developed knot mosaics to give a definition of a quantum knot system. This definition is intended to represent an actual physical quantum system.
Hong, Kyungpyo, Lee, Ho, Lee, Hwa Jeong, Oh, Seungsang   +3 more
core   +1 more source

A role for plant microtubules in the formation of transmission‐specific inclusion bodies of Cauliflower mosaic virus [PDF]

, 2008
Alexandre Martinière, Daniel Gargani, Marilyne Uzest, Nicole Lautrédou, Stéphane Blanc, Martin Drucker   +5 more
openalex   +1 more source

A Multi‐Step Deposition Strategy for β‐SiC Coatings on Cf/C Composites: Achieving Breakthrough Oxidation Resistance and Mechanical Properties

Advanced Science, EarlyView.
A new multi‐step β‐SiC deposition strategy for anti‐oxidation Cf/C composites successfully achieves dual‐performance breakthrough of anti‐oxidation property (≈700 h at 1500 °C)and mechanical property (bending strength of 215 MPa and adhesion strength of 9.4 MPa).
Dou Hu, Bing Liu, Xiaoxuan Li, Jia Sun, Tao Li, Yang Xu, Hejun Li, Qiangang Fu   +7 more
wiley   +1 more source