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Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hydatidiform mole (HM) is an abnormal human pregnancy, where the placenta presents with vesicular swelling of the chorionic villi. A fetus is either not present, or malformed and not viable. Most moles are diploid androgenetic as if one spermatozoon fertilized an empty oocyte, or triploid with one maternal and two paternal chromosome sets as if two ...
Sunde, Lone; id_orcid 0000-0002-8479-165X +6 more
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Cryptococcus neoformans is an environmental yeast that primarily affects immunocompromised individuals, causing respiratory infections and life-threatening meningoencephalitis. Treatment is complicated by limited antifungal options, with concerns such as
Eliane Vanhoffelen +5 more
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Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Localization systems are increasingly valuable, but their location estimates are only useful when the uncertainty of the estimate is known. This uncertainty is currently calculated as the location error given a ground truth, which is then used as a ...
Rafael Berkvens +2 more
doaj +1 more source
A group of edessa oriented mosaic panels exhibited in royal ontario museum
The theme of this article is the three mosaic pavements and we think that they are oriented from Edessa qanhurfa) which are exhibited in Toronto Royal Ontario Museum today. One of the three mosaics mentioned here called the Young Girl Mosaic. This mosaic
core +1 more source
Archaeometric Investigation of the Seasonal Mosaic of Antiochia
Hatay Arkeoloji Müzesinde sergilenen Mevsimler Mozaiği dokuz panelden oluşur ve dört köşesinde mevsimler tasvir edilir. Mevsimler Mozaiğinin üzerinde bulunan cam ve taş tesseraların renkleri Munsell Renk Kataloğu esas alınarak, dijital Odak marka Capsure
Ali ARGUNHAN +3 more
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Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Very little progress has been made during the last decade toward a theoretical understanding of the physical properties of matter in the solid state. The reasons for this stagnation are very clearly presented in a recent paper by A. Smekal.(1) According to Smekal, the properties of solids can be arranged in two large groups as follows.
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