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Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Identification of viruses in Gramineae growing in the neighbourhood of CIRAD's sugarcane quarantine in Montpellier, France [PDF]
CIRAD's sugarcane quarantine imports sugarcane varieties from different countries all over the world. These varieties, imported as cuttings or tissue-cultured plantlets, are likely to harbour pathogenic organisms and especially viruses.
Girard, Jean-Claude +2 more
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Creating Conditions for Innovation in a Complex Health System: A management practice analysis
As extended lifespans, rapid technological evolution and rising public expectations are increasing the complexity of our healthcare systems, health leaders need to innovate to gain sustainable improvements.
Sharon Mickan
doaj +1 more source
Period and toroidal knot mosaics
Knot mosaic theory was introduced by Lomonaco and Kauffman in the paper on `Quantum knots and mosaics' to give a precise and workable definition of quantum knots, intended to represent an actual physical quantum system.
Hong, Kyungpyo +4 more
core +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Pepino mosaic virus (PepMV) is a relatively new plant virus that has become a signifi cant agronomical problem in a relatively short period of time.
Vlugt, R.A.A., van der
core +1 more source
Steven Narod’s latest Countercurrents contribution to Current Oncology discusses a new breast and ovarian cancer susceptibility gene known as PPM1D. [...]
Foulkes, W.D., Real, F.X.
openaire +2 more sources
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Total Hemi-overgrowth in Pigmentary Mosaicism of the (Hypomelanosis of) Ito Type: Eight Case Reports. [PDF]
Pigmentary mosaicism of the (hypomelanosis of) Ito type is an umbrella term, which includes phenotypes characterized by mosaic hypopigmentation in the form of streaks, whorls, patchy, or more bizarre skin configurations (running along the lines of ...
Corsello G +8 more
core +1 more source

