Results 91 to 100 of about 68,629 (307)

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

Determination of Virus Diseases in Lettuce Production Areas of Ankara, Eskisehir, and Konya Provinces of Turkey

Yüzüncü Yıl Üniversitesi Tarim Bilimleri Dergisi, 2021
Winter vegetable cultivation is realized in several having suitable climate condition region of Turkey. Lettuce, an important winter crop for Turkey is cultivated in various provinces of the Central Anatolia Region.
Birol AKBAŞ, Ali Ferhan MORCA, Sevgi COŞKAN   +2 more
doaj   +1 more source

The Origin and Evolution of Viruses as Molecular Organisms

, 2009
Viruses are the most abundant life forms and the repertoire of viral genes is greater than that of cellular genes. It is also evident that viruses have played a major role in driving cellular evolution, and yet, viruses are not part of mainstream biology,
Claudiu I. Bandea
core  

Studies on the interaction between "Tobacco Mosaic Virus" movement protein and microtubules [PDF]

, 2003
During the invasion of a susceptible host, Tobacco mosaic virus (TMV) transports its RNA genome from sites of viral synthesis into neighbouring cells, thus potentiating the spread of infection.
Ashby, Jamie A.
core   +1 more source

Computational Intelligence Accelerates CRISPR‐Cas‐Based Diagnostic Design

iLABMED, EarlyView.
Computational intelligence, including pangenome‐guided target mining, machine‐learning‐based guide RNA optimization, and autonomous AI agents, is shifting CRISPR diagnostic design from empirical screening to systematic, data‐driven engineering and accelerating the path from pathogen discovery to deployable diagnostics.
Hengyu Wang, Qiurun He, Xuhu Mao, Yong Sheng   +3 more
wiley   +1 more source

Ultrasensitive nano-gold labelled, duplex lateral flow immunochromatographic assay for early detection of sugarcane mosaic viruses. [PDF]

Sci Rep, 2022
Thangavelu RM, Kadirvel N, Balasubramaniam P, Viswanathan R.   +3 more
europepmc   +1 more source

Viruses in Extreme Environments, Current Overview, and Biotechnological Potential

, 2021
Virus research has advanced significantly since the discovery of the tobacco mosaic virus (TMV), the characterization of its infection mechanisms and the factors that determine their pathogenicity.
Victoria Mesa, Andrés Gómez, Jose F. Gil, Gil, José F., Natalia Estrada-Ortiz, López Obando, Mauricio, Jersson Plácido, Estrada Ortiz, Natalia, Plácido, Jersson, Mauricio Lopez-Obando, Mesa Salgado, Victoria, Gómez, Andrés   +11 more
core   +1 more source

Navigating the future of nano‐pesticides: A perspective on design, efficacy, mechanisms, and environmental stewardship

iMeta, EarlyView.
Nano‐pesticides are driving a paradigm shift toward sustainable plant protection. This review systematically synthesizes recent advances across four interconnected domains: (i) intelligent formulation design for targeted delivery and controlled release; (ii) interfacial behavior regulation to enhance foliar deposition; (iii) multi‐omics elucidation of ...
Xile Deng, Feiying Zhu, Heng Qiao, Wenjie Shangguan, Qin Yu, Sandeep Sharma, Vijayakumar Shanmugam, Yanan Deng, Yudan Wu, Pengyue Zhao, Ullah Farman, Lidong Cao, Shuo Yan, Zhichao Dong, Lianyang Bai   +14 more
wiley   +1 more source

Simultaneous Detection of Both RNA and DNA Viruses Infecting Dry Bean and Occurrence of Mixed Infections by BGYMV, BCMV and BCMNV in the Central-West Region of Mexico

Viruses, 2017
A multiplex reverse transcription polymerase chain reaction (RT-PCR) assay was developed to simultaneously detect bean common mosaic virus (BCMV), bean common mosaic necrotic virus (BCMNV), and bean golden yellow mosaic virus (BGYMV) from common bean ...
Elizabeth Chiquito-Almanza, Jorge A. Acosta-Gallegos, Nadia C. García-Álvarez, Eduardo R. Garrido-Ramírez, Victor Montero-Tavera, Lorenzo Guevara-Olvera, José L. Anaya-López   +6 more
doaj   +1 more source