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L1 Mosaicism in Mammals: Extent, Effects, and Evolution [PDF]

open access: yesTrends in Genetics, 2017
The retrotransposon LINE-1 (long interspersed element 1, L1) is a transposable element that has extensively colonized the mammalian germline. L1 retrotransposition can also occur in somatic cells, causing genomic mosaicism, as well as in cancer. However,
Geoffrey J Faulkner   +1 more
exaly   +2 more sources
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The Mosaic of Rottlerin

The Journal of Organic Chemistry, 2015
The first total synthesis of rottlerin is described. The methodology allows the development of potential novel protein kinase C δ (PKCδ) analogues for better treatment of various diseases. Kamalachalcone A and dimeric rottlerin were synthesized in a very practical and economical way using FeCl3 as a catalyst.
Kenneth K C, Hong   +3 more
openaire   +2 more sources

Mosaics and Watersheds

2005
We investigate the effectiveness of the divide set produced by watershed algorithms. We introduce the mosaic to retrieve the altitude of points along the divide set. A desirable property is that, when two minima are separated by a crest in the original image, they are still separated by a crest of the same altitude in the mosaic. Our main result states
Najman, Laurent   +2 more
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The Big Mosaic

Current Anthropology, 1996
Compte-rendu du quatrieme et dernier atelier de recherche de l'European Science Foundation Network, qui s'est tenu a Pavlov (Republique Tcheque) du 12 au 14 octobre 1995, sur le theme de la situation climatique des 10000 dernieres annees et l'evaluation de son impact sur l'evolution culturelle des populations europeennes, notamment en ce qui concerne ...
MUSSI, Margherita, Wil Roebroeks
openaire   +1 more source

Video mosaics

Proceedings of the 2nd international symposium on Non-photorealistic animation and rendering, 2002
We present a method for creating a video mosaic, a two-dimensional arrangement of small source videos (tiles) that suggests a larger, unified target video. We develop a distance measure to assess the match between source and target based on average color and also three-dimensional wavelet decomposition signatures in the YIQ color space.
Allison W. Klein   +3 more
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A Mosaic of Software

2011 IEEE Seventh International Conference on eScience, 2011
In this paper we describe a Software Server, a background process that in conjunction with a central repository of lightweight wrapper scripts allows functionality within heterogeneous software to be called in a simple and consistent manner. The key role of the Software Server is to provide a common interface to software functionality in a manner that ...
Kenton McHenry   +4 more
openaire   +1 more source

Mosaicism in mammals

Genetica, 1959
Eighteen new cases of colour mosaics are described. Previous reports of mosaics are collocated and briefly discussed. Various mechanisms are described which may engender three types of mosaicism. These are the (1) somatic, (2) the soma-gonadic and (3) the gonadic.
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The Genetic Mosaic

Journal of the Royal Society of Medicine, 1993
Blaschko's lines are the acknowledged markers which represent the patterns of systematized naevi. Their interpretation has remained mysterious, because certain special features which they exhibit are impossible to reconcile with any known anatomical system in the human body.
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Mosaicism in pseudoachondroplasia

American Journal of Medical Genetics, 1997
Pseudoachondroplasia (PSACH) is a spondylo-epi-metaphyseal dysplasia characterized by disproportionate short stature, generalized ligamentous laxity, and precocious osteoarthritis. PSACH is caused by mutations in the cartilage oligomeric matrix protein (COMP) gene, which codes for a noncollagenous protein expressed in the territorial matrix of ...
H L, Ferguson   +5 more
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Pigmentary mosaicism

Clinics in Dermatology, 2022
Pigmentary mosaicism refers to patterned hypo- and/or hyperpigmentation that results from genetic heterogeneity of skin cells. The most common clinical patterns are streaks and swirls following Blaschko's lines in narrow or broad bands and a block-like distribution.
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