Results 241 to 250 of about 38,783 (308)

Proteomic profiling of Elp1‐deficient trigeminal ganglia reveals disruption of neurotrophic and metabolic pathways in a familial dysautonomia mouse model

Developmental Dynamics, EarlyView.
Abstract Background Elp1, a subunit of the Elongator complex, is essential for tRNA modification and neuronal development. Mutations in ELP1 underlie familial dysautonomia (FD), a disorder marked by sensory and autonomic neuropathy. While loss of Elp1 disrupts trigeminal ganglion formation and survival, the downstream molecular consequences remain ...
Carrie E. Leonard, Lauren Clarissa Tang, Beatrix Ueberheide, Lisa A. Taneyhill   +3 more
wiley   +1 more source

Low-level mosaic variants causing the pancreatic disease congenital hyperinsulinism can be detected from blood DNA. [PDF]

EBioMedicine
Bennett JJ, Laver TW, Männistö JME, Houghton JAL, De Franco E, Kalyon O, Wright S, Johnson AM, De Leon DD, Globa E, Kummer S, Banerjee I, Dastamani A, International Congenital Hyperinsulinism Consortium, Wakeling MN, Johnson MB, Flanagan SE.   +16 more
europepmc   +1 more source

Goofy/123Cre lineage tracing differentiates olfactory and vomeronasal neurons from GnRH‐1 and terminal nerve neurons during neuronal migration and reveals additional olfactory placode‐derived cells in the brain

Developmental Dynamics, EarlyView.
Abstract The olfactory placode (OP) generates a broad array of chemosensory neurons in the nasal region, including olfactory sensory neurons, vomeronasal sensory neurons, neurons of the septal organ, and Grueneberg ganglion. During invagination, the OP also generates migratory neuronal populations, including gonadotropin‐releasing hormone‐1 (GnRH‐1 ...
Enrico Amato Jr., Mia V. Call, Noah M. LeFever, Mya Aviles‐Carlos, Nikki M. Dolphin, Paolo E. Forni   +5 more
wiley   +1 more source

Changing patterns of colonisation and persistence during the wolf recolonisation of the human‐dominated Italian alpine region

Ecography, EarlyView.
Dynamic occupancy models are fundamental for understanding complex species recolonisation processes, as they allow the assessment of both colonisation and persistence probabilities over time. Using a dynamic occupancy model and a large‐scale multi‐year dataset on wolf presence collected in the Italian alpine region between 2014 and 2020, we analysed ...
M. V. Boiani, P. Dupont, R. Bischof, O. Friard, F. Bisi, G. Bombieri, S. Calderola, S. Carolfi, C. Chioso, L. Corlatti, U. Fattori, P. Ferrari, S. Filacorda, M. Geary, P. Molinari, E. Pernechele, D. Righetti, M. Tomasella, F. Truc, E. Avanzinelli, A. von Hardenberg, F. Marucco   +21 more
wiley   +1 more source

Citizen science deepens the ecological and climatic dimensions of mosquito surveillance

Ecography, EarlyView.
As mosquito‐borne diseases continue to expand worldwide, integrating citizen science into vector surveillance presents untapped potential. This study compares ecological models of Aedes albopictus, an invasive mosquito and global vector of dengue and other arboviruses, in Spain (2020–2022), using two contrasting data sources: traditional traps and ...
Catuxa Cerecedo‐Iglesias, John R. B. Palmer, Frederic Bartumeus   +2 more
wiley   +1 more source

Faster growing and more functionally diverse: global change alters functional trait composition of mountain plant communities in the European Alps

Ecography, EarlyView.
Understanding how global change reshapes mountain plant communities is essential for predicting biodiversity and ecosystem function in a warming world. Using resurvey data from over 1400 non‐forest vegetation plots across the European Alps, we show that community‐weighted means of key functional traits capturing important dimensions of plant ecological
Sergey Rosbakh, Sabine B. Rumpf, Stefan Dullinger   +2 more
wiley   +1 more source

Contaminant‐to‐Protection: In Situ Built Tri‐Component Barrier Enables Ultralong‐Cycling NASICON‐Based Sodium Metal Batteries

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Benefiting from the synergistic effect between the tri‐components, the hybrid interlayer can not only improve the wettability of NZSP to Na and promote the rapid migration of Na+ ions (Na3Sb with sodiophilic) but also effectively prevent the electron from intruding into the electrolyte at the interface and inhibit the growth of dendrites (NaCl and Na2O
Wenhao Tang, Ao Li, Zhengyang Wu, Shiyue Li, Ruiping Liu   +4 more
wiley   +1 more source

Dimensional Engineering of Wet‐Spun MOF‐Based Woven Fabrics for Superior Electromagnetic Wave Absorption

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This work fabricated MOF‐based woven absorbing fabrics with dimensional engineering via a wet spinning strategy. The absorbing fabrics achieve a reflection loss of −51.47 dB at 2.9 mm, with an effective absorption bandwidth reaching 3.54 GHz. The absorbing fabrics can be freely bent, stretched, and folded, with individual fibers exhibiting a break ...
Zihao Yan, Liyuan Guan, Qing Liu, Junhao Lin, Jianyong Yu, Bin Ding, Zhaoling Li   +6 more
wiley   +1 more source

Neonatal developmental and epileptic encephalopathy with movement disorder and arthrogryposis: A shared phenotype across brain‐expressed sodium channelopathies

Epilepsia, EarlyView.
Abstract Objective Neonatal developmental and epileptic encephalopathy with movement disorder and arthrogryposis (NDEEMA) represents the most severe end of the gain‐of‐function (GOF) SCN1A disorder spectrum. Sporadic cases of congenital arthrogryposis have also been reported in individuals with SCN2A‐, SCN3A‐, and SCN8A‐related developmental and ...
Sopio Gverdtsiteli, Sebastian Ortiz, Tobias Brünger, Francesca Furia, Carmen Barba, Trine Bjørg‐Hammer, Ingo Borggraefe, Roberto Caraballo, Sebahattin Cirak, Alberto Espeche, Walid Fazeli, Renzo Guerrini, Matias Juanes, Karin Kassahn, Maria Kinali, Johannes Krämer, Judith Kröll, Maria Concepción Miranda Herrero, Renske Oegema, Katrin Ounap, Oscar Peñuela, Konrad Platzer, Asuri Narayan Prasad, Aurora Pujol, Karit Reinson, Alfonso Represa, Eugenia Roza, Gabriela Reyes Valenzuela, Agustí Rodríguez‐Palmero, Suzanne Sallevelt, Maria Iciar Sanchez‐Albiusa, Ingrid E. Scheffer, Cory Smid, Carl E. Stafstrom, Eva‐Lena Stattin, Jen R. Suarez, Steffen Syrbe, Kette D. Valente, Matias Wagner, Saskia Wortmann, Elena Gardella, Dennis Lal, Andreas Brunklaus, Rikke S. Møller   +43 more
wiley   +1 more source

Mosaic embryos result in equivalent live birth rates when compared to euploid embryos following frozen embryo transfer. [PDF]

J Assist Reprod Genet
Sashitzky S, Rubin SC, Tetelbaun L, Robb C, Stern R, Bibi M, Rodriguez V, Greene A, Keltz M.   +8 more
europepmc   +1 more source