Results 51 to 60 of about 915,031 (303)

Impact of Aedes aegypti V1016I and F1534C knockdown resistance genotypes on operational interventions

Scientific Reports
Resistance to pyrethroids is common in Aedes aegypti populations. Mutations in the voltage gated sodium channel have an influence on the insecticide resistance (IR) phenotype.
Alden S. Estep, Neil D. Sanscrainte, Muhammad Farooq, Keira J. Lucas, Rebecca L. Heinig, Edmund J. Norris, James J. Becnel   +6 more
doaj   +1 more source

Development and field evaluation of a synthetic mosquito lure that is more attractive than humans. [PDF]

, 2010
BACKGROUND\ud \ud Disease transmitting mosquitoes locate humans and other blood hosts by identifying their characteristic odor profiles. Using their olfactory organs, the mosquitoes detect compounds present in human breath, sweat and skins, and use these
Killeen, G.F., Ngonyani, Hassan, Fredros O Okumu, Edgar Mbeyela, Smallegange, R.C., Moore, Sarah J., Ogoma, Sheila, Munk, Cristina, Mukabana, Wolfgang R., Ngonyani, H., Mbeyela, Edgar, Ogoma, S., Cristina Munk, Emmanuel Titus, Hassan Mshinda, Moore, S.J., Sheila Ogoma, Killeen, Gerry F, Sarah J Moore, Wolfgang R Mukabana, Takken, W., Okumu, Fredros O, Mshinda, Hassan, Mukabana, W.R., Okumu, Fredros O., Okumu, F.O., Lubandwa Biswaro, Moore, Sarah J, Munk, C., Smallegange, Renate C, Gerry F Killeen, Renate C Smallegange, Titus, E., Titus, Emmanuel, Takken, Willem, Mukabana, Wolfgang R, Hassan Ngonyani, Mbeyela, E., Killeen, Gerry F., Mshinda, H., Biswaro, Lubandwa, Biswaro, L., Smallegange, Renate C., Willem Takken   +43 more
core   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Does Mosquito Control Have an Effect on Mosquito-Borne Disease? The Case of Ross River Virus Disease and Mosquito Management in Queensland, Australia

, 2011
We examined the relationship between types of mosquito control programs and the mosquito-borne Ross River virus (RRV) disease in Queensland, Australia.
Tomerini, Deanna, Pat E. Dale, Neil Sipe, Dale, Pat E, Dale, Patricia, Deanna M. Tomerini, Tomerini, Deanna M, Tomerini, Deanna M., Sipe, Neil, Dale, Pat E.   +9 more
core   +1 more source

Repurposing Drugs for Malaria through a Human Dose Prediction: A Case Study with Berzosertib

Clinical Pharmacology &Therapeutics, EarlyView.
Repurposing drugs whose clinical safety has been established offers a valuable approach to reduce the cost and time associated with the development of new drugs for malaria. Here, we investigate the potential to repurpose the anticancer kinase inhibitor berzosertib for the treatment of malaria, by assessing whether a predicted efficacious human dose ...
Devasha Redhi, Mwila Mulubwa, Mmakwena M. Mmonwa, Mathew Njoroge, Liezl Krugmann, Kelly Chibale   +5 more
wiley   +1 more source

Barcoding Quantitative PCR Assay to Distinguish Between Aedes aegypti and Aedes sierrensis

Tropical Medicine and Infectious Disease
The accurate identification of mosquito species is critical for effective mosquito surveillance and control, especially when presented with morphologically similar species like Aedes aegypti and Aedes sierrensis.
Miguel Barretto, Annika Olson, Dereje Alemayehu, Ryan Clausnitzer, Eric J. Haas-Stapleton   +4 more
doaj   +1 more source

Disruption of spatiotemporal clustering in dengue cases by wMel Wolbachia in Yogyakarta, Indonesia

Scientific Reports, 2022
Dengue exhibits focal clustering in households and neighborhoods, driven by local mosquito population dynamics, human population immunity, and fine scale human and mosquito movement.
Suzanne M. Dufault, Stephanie K. Tanamas, Citra Indriani, Adi Utarini, Riris Andono Ahmad, Nicholas P. Jewell, Cameron P. Simmons, Katherine L. Anders   +7 more
doaj   +1 more source

Mosquitoes and Malaria [PDF]

Nature, 1948
WITH reference to the recent article on the Ronald Ross Jubilee1, it may be of interest to note that, in a paper read at a meeting of the Royal Scottish Geographical Society in April 1892, Dr. H. Martyn Clark, of Amritsar, remarked "that, as some insects carry the pollen of one plant to the flower of another, so mosquitos [sic] transplant the malarial ...
openaire   +2 more sources

Viral Dynamic Model‐Informed Dose Selection of Mosnodenvir Prophylaxis against DENV‐3 in a Controlled Human Infection Model

Clinical Pharmacology &Therapeutics, EarlyView.
Dengue virus (DENV) infection is a significant global health threat. Mosnodenvir (JNJ‐64281802) is a pan‐serotype small molecule antiviral blocking DENV replication. A Phase IIa study (NCT05048875) evaluated the antiviral activity, safety, and pharmacokinetics of mosnodenvir as prophylaxis against DENV‐3 in a controlled human infection model (CHIM).
Nele Goeyvaerts, Xavier Woot de Trixhe, Martine Neyens, Thomas N. Kakuda, Liesbeth Van Wesenbeeck, Annemie Buelens, Freya Rasschaert, Anna Durbin, Oliver Ackaert   +8 more
wiley   +1 more source

Evaluation of Ground and Aerial Ultra-Low Volume Applications Using ReMoa Tri Against Deltamethrin-Resistant Aedes aegypti from Collier County, Florida

Tropical Medicine and Infectious Disease
New intervention methods and product formulations are needed to better control pyrethroid-resistant Aedes aegypti populations and mitigate the risk of mosquito-borne disease.
Decyo McDuffie, Sara Kacinskas, Suzanne Li, Casey Parker-Crockett, Keira J. Lucas   +4 more
doaj   +1 more source