Human IDO2 exhibits unique binding affinities distinct to those of human IDO1
Although indoleamine 2,3‐dioxygenase 2 (IDO2) is highly homologous to IDO1, it displays markedly lower catalytic activity. We found that IDO2 binds L‐tryptophan (L‐Trp) in a flipped orientation stabilized by the IDO2‐specific residue His143. Replacement of His143 with the IDO1‐equivalent tyrosine restored an IDO1‐like binding mode and increased ...
Shunsuke Nogi +8 more
wiley +1 more source
Unraveling the active site cover of coproheme decarboxylase from Listeria monocytogenes
During heme biosynthesis in Gram‐positive bacteria, coproheme decarboxylase (ChdC) catalyzes the conversion of four‐propionate substrate coproheme to the two propionate product heme b. Its active site is universally covered by a flexible linking loop. This study identifies an important histidine residue, which stabilizes the loop in a ChdC homolog.
Nikolaus Falb +4 more
wiley +1 more source
Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi +4 more
wiley +1 more source
Fish Poxviruses on the Rise: Prospects for Aquatic Health
ABSTRACT Fish poxviruses are increasingly recognised as emerging pathogens of fish and should be considered in cases of unexplained gill or skin pathology. Carp edema virus (CEV), the causative agent of koi sleepy disease in common carp and koi (Cyprinus carpio), represents the first known example.
Mikolaj Adamek +9 more
wiley +1 more source
Bio-ecological study of Aedes aegypti in urban ecosystems in Merida state, Venezuela 1996-1998
In order to evaluate certain bio-ecological aspects of Aedes aegypti in the urban ecosystem in Merida State, adults of the species were captured and larva counts were made in 30% the housing units in localities of this region.
Janeth Rojas Urdaneta +4 more
doaj
Epidemiological outlook for vector-borne diseases: Learned lessons and challenges to break the circle [PDF]
Padilla-Rodríguez JC.
europepmc +1 more source
Confirming the impact origin of the São Miguel do Tapuio structure, northeastern Brazil
Abstract The São Miguel do Tapuio structure (SMT) is a remarkable, nearcircular feature of about 21 km diameter, centered at 5°37.6′ S, 41°23.3′ W in Piauí state, northeastern Brazil. The structure is located within the sedimentary strata of the Paleozoic–Mesozoic Parnaíba Basin and predominantly comprises sandstones of the Devonian Pimenteiras and ...
Alvaro Penteado Crósta +9 more
wiley +1 more source
Se llevaron a cabo pruebas de laboratorio para demostrar la eficacia del mermítido Romanomermis iyengari como agente biorregulador de larvas de Culex quinquefasciafus y Anopheles albimanus vectores de filariasis y de malaria en el área del Caribe.
V Soto Alvarez, A Santamarina Mijares
doaj
La contabilización de huevos de mosquitos en campo requiere de tiempo y personal operativo con experiencia, y en algunos casos, la ayuda de costosos equipos de laboratorio.
Walter Eduardo Quezada-Yaguachi +10 more
doaj +1 more source
Evaluación del efecto insecticida de terpenos obtenidos de plantas comestibles y medicinales sobre Aedes aegypti L. (Diptera: Culicidae). [PDF]
Tesina (Grado en Ciencias Biológicas)--Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Lugar de Trabajo: Laboratorio de la Cátedra de Entomología. 2018. 26 h.; ils.; grafs.; tabls.
Flores, Guillermo Alejandro Maximo
core

