Results 61 to 70 of about 1,816,378 (344)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Primary hydatid cyst of the neck – EPSC 101593

Journal of Pediatric Surgery Case Reports, 2020
Hydatid cyst is a parasitic infection mostly caused by Echinococcus granulosis. The most frequent sites of the cyst are liver and lungs. Occurrence in the head and neck region is extremely rare.
Mohammad Tareq Rahimi, Reshadullah Jurat, Mohammad Akbar Shirzad, Haseeb Rahman   +3 more
doaj   +1 more source

Posttraumatic Stress and Parenting Behaviors: The Mediating Role of Emotion Regulation [PDF]

, 2019
Maternal trauma has been linked with problematic parenting, including both harsh and permissive behaviors. However, little is known about mechanisms accounting for this association.
Brock, Rebecca L., DiLillo, David, Franz, Molly R., Kumar, Shaina A.   +3 more
core   +2 more sources

Autosomal Recessive Spastic Ataxia of Charlevoix‐Saguenay in Two Half‐Siblings

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Autosomal recessive spastic ataxia of Charlevoix‐Saguenay (ARSACS) is caused by biallelic pathogenic variants in the SACS gene. We report the clinical, radiologic and neurophysiologic features of a pair of half‐siblings who presented with progressive cerebellar ataxia, peripheral neuropathy and upper motor neuron signs.
Dennis Yeow, Matthew Katz, Jonathan Rodgers, Mark Davis, Thomas Robertson, R. J. McKinlay Gardner, Pamela A. McCombe   +6 more
wiley   +1 more source

Building a Guaranteed Income to End the "Child Welfare" System

Columbia Journal of Race and Law, 2022
It is time for policemakers to reimagine and dismantle the child welfare system. This Article provides background on disparities in the child welfare system and argues that policymakers have used the child welfare system to police poverty and regulate ...
Melody Webb
doaj   +1 more source

Prevalence and Correlates of Common Mental Disorders among Mothers of Young Children in Kilimanjaro Region of Tanzania. [PDF]

, 2012
Although poor maternal mental health is a major public health problem, with detrimental effects on the individual, her children and society, information on its correlates in low-income countries is sparse. This study investigates the prevalence of common
A Bhagwanjee, A Rahman, A Rahman, A Sawyer, Amina Abubakar, AO Adewuya, AT Paffer, Babill Stray-Pedersen, BL Genberg, BS Ali, CM McKinney, F Rabbani, G Antelman, I Mirza, IL Pike, J Fisher, J Mbatia, Jacqueline G. Uriyo, James Coyne, JE Nakku, M Amuri, M Ellsberg, M Winston, Mark Swai, MB Nayak, MM Black, MZ Podolska, MZ Podolska, N Deyessa, N Husain, NS Ali, NS Ali, OA Abiodun, Patel, R Coleman, RC Stewart, Roos, SF Kaaya, Sia E. Msuya, T Abramsky, V Patel, V Patel, V Patel, WC Leung, Z Simsek   +44 more
core   +4 more sources

Persistent Leukoencephalopathy Following H1N1 Infection Associated With a Novel MYRF Variant (p.Gly735Asp)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu, Leiyun Huang, Wan Zhu, Min Peng, Qiang Gong, Jing Qian   +5 more
wiley   +1 more source

Methylation of the Corticotropin Releasing Hormone Gene Promoter in BeWo Cells: Relationship to Gene Activity

International Journal of Endocrinology, 2015
Corticotropin releasing hormone (CRH) production by the human placenta increases exponentially as pregnancy advances, and the rate of increase predicts gestational length.
Xin Pan, Maria Bowman, Rodney J. Scott, John Fitter, Richard C. Nicholson, Roger Smith, Tamas Zakar   +6 more
doaj   +1 more source

Late presentation, MR imaging features and surgical treatment of Herlyn-Werner-Wunderlich syndrome (classification 2.2); a case report

BMC Women's Health, 2018
Background Herlyn-Werner-Wunderlich syndrome is a very rare congenital genitourinary anomaly characterized by uterus didelphys, blind hemivagina and ipsilateral renal agenesis. Case presentation Authors present a case of Herlyn-Werner-Wunderlich syndrome
Hidayatullah Hamidi, Nilab Haidary
doaj   +1 more source

Parents’ Experience in an Italian NICU Implementing NIDCAP-Based Care: A Qualitative Study

Children, 2022
Background: The birth of a preterm infant and his/her immediate admittance to the Neonatal Intensive Care Unit (NICU) are sudden, unexpected, stressful and painful events for parents.
Natascia Bertoncelli, Licia Lugli, Luca Bedetti, Laura Lucaccioni, Arianna Bianchini, Alessandra Boncompagni, Federica Cipolli, Anna Cinzia Cosimo, Giovanna Cuomo, Michela Di Giuseppe, Tamara Lelli, Veronica Muzzi, Martina Paglia, Lucia Pezzuti, Claudia Sabbioni, Francesca Salzone, Maria Cristina Sorgente, Fabrizio Ferrari, Alberto Berardi   +18 more
doaj   +1 more source