Results 131 to 140 of about 577,004 (315)
QuateXelero : an accelerated exact network motif detection algorithm
, 2013 Finding motifs in biological, social, technological, and other types of networks has become a widespread method to gain more knowledge about these networks’ structure and function.
Dichter, Norbert +9 more
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
HyPaLib: a database of RNAs and RNA structural elements defined by hybrid patterns
, 2001 Gräf S, Strothmann D, Kurtz S, Steger G. HyPaLib: a database of RNAs and RNA structural elements defined by hybrid patterns. Nucleic Acids Research.
Strothmann, Dirk +3 more
core +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
f-catégories, tours et motifs de Tate
, 2008 International audienceLe but de cette note est de donner une preuve simple de l'énoncé suivant : sur un corps algébrique sur Q, la catégorie triangulée des motifs de Tate est équivalente à la catégorie dérivée bornée de son ...
Jörg Wildeshaus, Wildeshaus, Jörg
core +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Exon-phase symmetry and intrinsic structural disorder promote modular evolution in the human genome
, 2013 A key signature of module exchange in the genome is phase symmetry of exons, suggestive of exon shuffling events that occurred without disrupting translation reading frame.
Kalmár, Lajos +2 more
core +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
A Bioinformatics Approach for Detecting Repetitive Nested Motifs using Pattern Matching [PDF]
, 2016 The identification of nested motifs in genomic sequences is a complex computational problem. The detection of these patterns is important to allow discovery of transposable element (TE) insertions, incomplete reverse transcripts, deletions, and/or ...
Romero, José Rodolfo +4 more
core
Allergen motifs and the prediction of allergenicity
, 2007 We have recently shown that the majority of allergens can be represented by allergen motifs. This observation prompted us to experimentally investigate the synthesized peptides corresponding to the in silico motifs with regard to potential IgE binding ...
Mari, Adriano +19 more
core +1 more source