Results 131 to 140 of about 1,416,450 (324)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
MUSICAL COMPOSITION AND ELEMENTARY EXCITATIONS OF THE ENVIRONMENT [PDF]
Interdisciplinary Description of Complex Systems, 2003 During the performance of a musical composition a special human environment comes into being. We aim to interpret the compositions as a specific class of human environment in order to utilise that for description of structure and dynamics of general ...
Damir Pajic +2 more
doaj
GPS-SUMO: a tool for the prediction of sumoylation sites and SUMO-interaction motifs
Nucleic Acids Res., 2014 Small ubiquitin-like modifiers (SUMOs) regulate a variety of cellular processes through two distinct mechanisms, including covalent sumoylation and non-covalent SUMO interaction.
Qi Zhao +9 more
semanticscholar +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
MOTIF CERITA RAKYAT SEBAGAI SARANA PENJAGA INTEGRITAS SOSIAL MASYARAKAT ASEAN
Waskita: Jurnal Pendidikan Nilai dan Pembangunan Karakter, 2019 Folklore is a traditional story to convey the noble values of a region to the future generations which are delivered using spoken language. The focus of this study are (1) the motifs and variations of Malin Kundang folklore in various ASEAN countries ...
Lilik Wahyuni
doaj +1 more source
Flexible multitask computation in recurrent networks utilizes shared dynamical motifs
bioRxiv, 2022 Laura N. Driscoll +2 more
semanticscholar +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source