Results 111 to 120 of about 1,416,450 (324)
“All That Was Lost Is Revealed”: Motifs and Moral Ambiguity in Over the Garden Wall
Humanities, 2016 Pointedly nostalgic in both its source material and storytelling approach, Over the Garden Wall’s vintage aesthetic is not merely decorative, but ideological. The miniseries responds to recent postmodern fairy tale adaptations by stripping away a century
Kristiana Willsey
doaj +1 more source
Industrial Conference on Data Mining, 2016 Time series motifs have been in the literature for about fifteen years, but have only recently begun to receive significant attention in the research community. This is perhaps due to the growing realization that they implicitly offer solutions to a host
Yan Zhu +7 more
semanticscholar +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
, 2014 Next-generation sequencing technology enables the identification of thousands of gene regulatory sequences in many cell types and organisms. We consider the problem of testing if two such sequences differ in their number of binding site motifs for a ...
Friedrich, Tara +3 more
core +1 more source
ATtRACT—a database of RNA-binding proteins and associated motifs
Database J. Biol. Databases Curation, 2016 RNA-binding proteins (RBPs) play a crucial role in key cellular processes, including RNA transport, splicing, polyadenylation and stability. Understanding the interaction between RBPs and RNA is key to improve our knowledge of RNA processing ...
Girolamo Giudice +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
In Silico Approach for Prediction of Antifungal Peptides
Frontiers in Microbiology, 2018 This paper describes in silico models developed using a wide range of peptide features for predicting antifungal peptides (AFPs). Our analyses indicate that certain types of residue (e.g., C, G, H, K, R, Y) are more abundant in AFPs.
Piyush Agrawal +6 more
doaj +1 more source
Survival analysis of DNA mutation motifs with penalized proportional hazards
, 2018 Antibodies, an essential part of our immune system, develop through an intricate process to bind a wide array of pathogens. This process involves randomly mutating DNA sequences encoding these antibodies to find variants with improved binding, though ...
Feng, Jean +4 more
core +2 more sources
The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) family
Genome Biology, 2015 The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) enzymes are secreted, multi-domain matrix-associated zinc metalloendopeptidases that have diverse roles in tissue morphogenesis and patho-physiological remodeling, in ...
R. Kelwick +3 more
semanticscholar +1 more source