Results 91 to 100 of about 577,004 (315)

The Usage of Scriptural Nativity Motifs in Early Greek and Slavonic Hymnography

open access: yes, 2023
In this article I will make a survey of the usage of the main nativity motifs that can be found in early Greek and Slavonic hymnography, such as the kata stichon hymns.
Santos Marinas, Enrique
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Computational identification and analysis of protein short linear motifs

open access: yes, 2010
Short linear motifs (SLiMs) in proteins can act as targets for proteolytic cleavage, sites of post-translational modification, determinants of sub-cellular localization, and mediators of protein-protein interactions.
Davey, Norman E.   +2 more
core  

Decoding the Terracotta Tablet Found in Shadyakh Islamic Site of Neishabour [PDF]

open access: yesنگره, 2015
Symbols have broader functions in the Islamic era in comparison to the pre-Islamic time, the cause of which may be the change of religion and spiritual approach that occurred in the Islamic world.
Abbas Sheikhi, Leila Ghafarpoor
doaj  

A Study of the Reflection of Qur'anic Verses in Mihrab Carpets of the Safavid Period [PDF]

open access: yesقرآن فرهنگ و تمدن
Among the significant decorative elements in Safavid carpets-representing a fusion of Islamic art and culture-is the use of inscriptions containing Qur’anic verses, poetry, or supplications.
Elaheh Panjahbashi, Rana Mohammadzadeh
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Cryptococcus neoformans serotype A virulence and pathogenicity are capsular glucuronoxylomannan (GXM) motif composition dependent

open access: yesmBio
The Cryptococcus neoformans capsular extracellular polysaccharide (EPS) plays an essential role in virulence and host immunomodulation. In this study, we analyzed the virulence of four serotype A C.
Samuel Rodrigues Dos Santos Junior   +8 more
doaj   +1 more source

“All That Was Lost Is Revealed”: Motifs and Moral Ambiguity in Over the Garden Wall

open access: yesHumanities, 2016
Pointedly nostalgic in both its source material and storytelling approach, Over the Garden Wall’s vintage aesthetic is not merely decorative, but ideological. The miniseries responds to recent postmodern fairy tale adaptations by stripping away a century
Kristiana Willsey
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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