Results 61 to 70 of about 420,339 (255)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
mBioThe Cryptococcus neoformans capsular extracellular polysaccharide (EPS) plays an essential role in virulence and host immunomodulation. In this study, we analyzed the virulence of four serotype A C.
Samuel Rodrigues Dos Santos Junior +8 more
doaj +1 more source
A Study of the Reflection of Qur'anic Verses in Mihrab Carpets of the Safavid Period [PDF]
قرآن فرهنگ و تمدنAmong the significant decorative elements in Safavid carpets-representing a fusion of Islamic art and culture-is the use of inscriptions containing Qur’anic verses, poetry, or supplications.
Elaheh Panjahbashi, Rana Mohammadzadeh
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Combinatorial expression motifs in signaling pathways
Cell GenomicsSummary: In animal cells, molecular pathways often comprise families of variant components, such as ligands or receptors. These pathway components are differentially expressed by different cell types, potentially tailoring pathway function to cell ...
Alejandro A. Granados +2 more
doaj +1 more source
“All That Was Lost Is Revealed”: Motifs and Moral Ambiguity in Over the Garden Wall
Humanities, 2016 Pointedly nostalgic in both its source material and storytelling approach, Over the Garden Wall’s vintage aesthetic is not merely decorative, but ideological. The miniseries responds to recent postmodern fairy tale adaptations by stripping away a century
Kristiana Willsey
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
In Silico Approach for Prediction of Antifungal Peptides
Frontiers in Microbiology, 2018 This paper describes in silico models developed using a wide range of peptide features for predicting antifungal peptides (AFPs). Our analyses indicate that certain types of residue (e.g., C, G, H, K, R, Y) are more abundant in AFPs.
Piyush Agrawal +6 more
doaj +1 more source