Results 1 to 10 of about 11,872 (202)
The regulation of mechanosensory motile cilium formation [PDF]
Cilia, 2015 In contrast to the progress in understanding ciliogenesis and cilium function, we know less about the pathways for generating ciliary diversity. Drosophila has a variety of sensory neurons with ciliary dendrites that are structurally and functionally specialised for receiving different sensory modalities.
Jarman A, Lage P, Mali G, Mill P.
europepmc +5 more sources
Ciliary chemosensitivity is enhanced by cilium geometry and motility
eLife, 2021 Cilia are hairlike organelles involved in both sensory functions and motility. We discuss the question of whether the location of chemical receptors on cilia provides an advantage in terms of sensitivity and whether motile sensory cilia have a further ...
David Hickey +2 more
doaj +5 more sources
The primary cilium as a multifunctional organelle: emerging roles and unanswered questions [PDF]
Cell Communication and SignalingThe primary cilium, a solitary membrane-bound, microtubule-based cellular organelle, has been considered an evolutionary relict for almost a century. Over the past three decades, interest in this protruding, non-motile structure of the plasma membrane ...
Denis Corbeil +4 more
doaj +2 more sources
Insights into centriole geometry revealed by cryotomography of doublet and triplet centrioles [PDF]
eLife, 2018 Centrioles are cylindrical assemblies comprised of 9 singlet, doublet, or triplet microtubules, essential for the formation of motile and sensory cilia.
Garrett A Greenan +3 more
doaj +4 more sources
GJA1 depletion causes ciliary defects by affecting Rab11 trafficking to the ciliary base
eLife, 2022 The gap junction complex functions as a transport channel across the membrane. Among gap junction subunits, gap junction protein α1 (GJA1) is the most commonly expressed subunit.
Dong Gil Jang +8 more
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eLife, 2023 Cilia, either motile or non-motile (a.k.a primary or sensory), are complex evolutionarily conserved eukaryotic structures composed of hundreds of proteins required for their assembly, structure and function that are collectively known as the ciliome ...
Rebeca Brocal-Ruiz +7 more
doaj +1 more source
Pathophysiology of Primary Cilia: Signaling and Proteostasis Regulation
Frontiers in Cell and Developmental Biology, 2022 Primary cilia are microtubule-based, non-motile sensory organelles present in most types of growth-arrested eukaryotic cells. They are transduction hubs that receive and transmit external signals to the cells in order to control growth, differentiation ...
Emanuela Senatore +5 more
doaj +1 more source
Bioengineering, 2022 Motile cilia are hair-like microscopic structures which generate directional flow to provide fluid transport in various biological processes. Ciliary beating is one of the sources of cerebrospinal flow (CSF) in brain ventricles.
Huseyin Enes Salman +2 more
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BMC Cancer, 2023 Background Prostate cancer is a common solid tumor that affects a significant number of men worldwide. Conventional androgen deprivation therapy (ADT) increases the risk of developing castration-resistant prostate cancer (CRPC).
Xingchen Dai +4 more
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Diagnostics, 2021 Chronic obstructive pulmonary disease (COPD) is a frequent respiratory disease. However, its pathophysiology remains partially elucidated. Epithelial remodeling including alteration of the cilium is a major hallmark of COPD, but specific assessments of ...
Julien Ancel +10 more
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