Results 1 to 10 of about 11,874 (154)
The regulation of mechanosensory motile cilium formation [PDF]
Cilia, 2015 In contrast to the progress in understanding ciliogenesis and cilium function, we know less about the pathways for generating ciliary diversity. Drosophila has a variety of sensory neurons with ciliary dendrites that are structurally and functionally specialised for receiving different sensory modalities.
Jarman A, Lage P, Mali G, Mill P.
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Ciliary chemosensitivity is enhanced by cilium geometry and motility
eLife, 2021 Cilia are hairlike organelles involved in both sensory functions and motility. We discuss the question of whether the location of chemical receptors on cilia provides an advantage in terms of sensitivity and whether motile sensory cilia have a further ...
David Hickey +2 more
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Sensorium: The Original Raison D'etre of the Motile Cilium? [PDF]
Journal of Molecular Cell Biology, 2009 The role of non-motile (primary) cilia as sensory antennae critical for metazoan development and physiology has surfaced over the last decade, long after the function of motile cilia in propelling cells or moving fluids across tissues was well established.
Lynne M. Quarmby, Michel R. Leroux
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The motile cilium in development and disease: emerging new insights [PDF]
BioEssays, 2009 AbstractIn this paper, I review a collection of recently published papers that have provided significant new information about the biogenesis and functions of motile cilia. In vertebrates, the activity of motile cilia has been associated with a fascinating diversity of developmental and physiological processes.
Sudipto Roy
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DrosophilaBld10 Is a Centriolar Protein That Regulates Centriole, Basal Body, and Motile Cilium Assembly [PDF]
Molecular Biology of the Cell, 2009 Cilia and flagella play multiple essential roles in animal development and cell physiology. Defective cilium assembly or motility represents the etiological basis for a growing number of human diseases. Therefore, how cilia and flagella assemble and the processes that drive motility are essential for understanding these diseases.
Violaine Mottier-Pavie +1 more
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Live cell imaging of dynamic behaviors of motile cilia and primary cilium
Microscopy, 2018 The cilium is a tiny organelle, with a length of 1-10 μm and a diameter of ~200 nm, that projects from the surface of many cells and functions to generate fluid flow and/or sense extracellular signals from the environment. Abnormalities in cilia may cause a broad spectrum of disease, i.e. the so-called ciliopathies.
Faryal Ijaz, Koji Ikegami
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The primary cilium as a multifunctional organelle: emerging roles and unanswered questions [PDF]
Cell Communication and SignalingThe primary cilium, a solitary membrane-bound, microtubule-based cellular organelle, has been considered an evolutionary relict for almost a century. Over the past three decades, interest in this protruding, non-motile structure of the plasma membrane ...
Denis Corbeil +4 more
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Insights into centriole geometry revealed by cryotomography of doublet and triplet centrioles [PDF]
eLife, 2018 Centrioles are cylindrical assemblies comprised of 9 singlet, doublet, or triplet microtubules, essential for the formation of motile and sensory cilia.
Garrett A Greenan +3 more
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GJA1 depletion causes ciliary defects by affecting Rab11 trafficking to the ciliary base
eLife, 2022 The gap junction complex functions as a transport channel across the membrane. Among gap junction subunits, gap junction protein α1 (GJA1) is the most commonly expressed subunit.
Dong Gil Jang +8 more
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eLife, 2023 Cilia, either motile or non-motile (a.k.a primary or sensory), are complex evolutionarily conserved eukaryotic structures composed of hundreds of proteins required for their assembly, structure and function that are collectively known as the ciliome ...
Rebeca Brocal-Ruiz +7 more
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