The regulation of mechanosensory motile cilium formation [PDF]
Cilia, 2015 In contrast to the progress in understanding ciliogenesis and cilium function, we know less about the pathways for generating ciliary diversity. Drosophila has a variety of sensory neurons with ciliary dendrites that are structurally and functionally specialised for receiving different sensory modalities.
Jarman A, Lage P, Mali G, Mill P.
europepmc +6 more sources
Ciliary chemosensitivity is enhanced by cilium geometry and motility [PDF]
eLife, 2021 Cilia are hairlike organelles involved in both sensory functions and motility. We discuss the question of whether the location of chemical receptors on cilia provides an advantage in terms of sensitivity and whether motile sensory cilia have a further ...
David Hickey +2 more
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Sensorium: The Original Raison D'etre of the Motile Cilium? [PDF]
Journal of Molecular Cell Biology, 2009 The role of non-motile (primary) cilia as sensory antennae critical for metazoan development and physiology has surfaced over the last decade, long after the function of motile cilia in propelling cells or moving fluids across tissues was well established.
Lynne M. Quarmby, Michel R. Leroux
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DrosophilaBld10 Is a Centriolar Protein That Regulates Centriole, Basal Body, and Motile Cilium Assembly [PDF]
Molecular Biology of the Cell, 2009 Cilia and flagella play multiple essential roles in animal development and cell physiology. Defective cilium assembly or motility represents the etiological basis for a growing number of human diseases. Therefore, how cilia and flagella assemble and the processes that drive motility are essential for understanding these diseases.
Violaine Mottier-Pavie +1 more
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The motile cilium in development and disease: emerging new insights [PDF]
BioEssays, 2009 AbstractIn this paper, I review a collection of recently published papers that have provided significant new information about the biogenesis and functions of motile cilia. In vertebrates, the activity of motile cilia has been associated with a fascinating diversity of developmental and physiological processes.
Sudipto Roy
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Live cell imaging of dynamic behaviors of motile cilia and primary cilium
Microscopy, 2018 The cilium is a tiny organelle, with a length of 1-10 μm and a diameter of ~200 nm, that projects from the surface of many cells and functions to generate fluid flow and/or sense extracellular signals from the environment. Abnormalities in cilia may cause a broad spectrum of disease, i.e. the so-called ciliopathies.
Faryal Ijaz, Koji Ikegami
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Spontaneous creation of macroscopic flow and metachronal waves in an array of cilia [PDF]
, 2006 Cells or bacteria carrying cilia on their surface show many striking features : alignment of cilia in an array, two-phase asymmetric beating for each cilium, coordination between cilia and existence of metachronal waves with a constant phase difference between two adjacent cilia.
Guirao, Boris, Joanny, Jean-François
arxiv +5 more sources
Insights into centriole geometry revealed by cryotomography of doublet and triplet centrioles [PDF]
eLife, 2018 Centrioles are cylindrical assemblies comprised of 9 singlet, doublet, or triplet microtubules, essential for the formation of motile and sensory cilia.
Garrett A Greenan +3 more
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C. elegans PPEF-type phosphatase (Retinal degeneration C ortholog) functions in diverse classes of cilia to regulate nematode behaviors [PDF]
Scientific ReportsPrimary (non-motile) cilia represent structurally and functionally diverse organelles whose roles as specialized cellular antenna are central to animal cell signaling pathways, sensory physiology and development.
Marine Barbelanne +9 more
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GJA1 depletion causes ciliary defects by affecting Rab11 trafficking to the ciliary base
eLife, 2022 The gap junction complex functions as a transport channel across the membrane. Among gap junction subunits, gap junction protein α1 (GJA1) is the most commonly expressed subunit.
Dong Gil Jang +8 more
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