Results 11 to 20 of about 58,452 (246)
The regulation of mechanosensory motile cilium formation [PDF]
Cilia, 2015 In contrast to the progress in understanding ciliogenesis and cilium function, we know less about the pathways for generating ciliary diversity. Drosophila has a variety of sensory neurons with ciliary dendrites that are structurally and functionally specialised for receiving different sensory modalities.
Jarman A, Lage P, Mali G, Mill P.
europepmc +7 more sources
Sensorium: The Original Raison D'etre of the Motile Cilium? [PDF]
Journal of Molecular Cell Biology, 2009 The role of non-motile (primary) cilia as sensory antennae critical for metazoan development and physiology has surfaced over the last decade, long after the function of motile cilia in propelling cells or moving fluids across tissues was well established.
Lynne M. Quarmby, Michel R. Leroux
semanticscholar +5 more sources
Ciliary chemosensitivity is enhanced by cilium geometry and motility [PDF]
eLife, 2021 Cilia are hairlike organelles involved in both sensory functions and motility. We discuss the question of whether the location of chemical receptors on cilia provides an advantage in terms of sensitivity and whether motile sensory cilia have a further ...
David Hickey +2 more
doaj +5 more sources
DrosophilaBld10 Is a Centriolar Protein That Regulates Centriole, Basal Body, and Motile Cilium Assembly [PDF]
Molecular Biology of the Cell, 2009 Cilia and flagella play multiple essential roles in animal development and cell physiology. Defective cilium assembly or motility represents the etiological basis for a growing number of human diseases. Therefore, how cilia and flagella assemble and the processes that drive motility are essential for understanding these diseases.
Violaine Mottier-Pavie +1 more
semanticscholar +5 more sources
The motile cilium in development and disease: emerging new insights [PDF]
BioEssays, 2009 AbstractIn this paper, I review a collection of recently published papers that have provided significant new information about the biogenesis and functions of motile cilia. In vertebrates, the activity of motile cilia has been associated with a fascinating diversity of developmental and physiological processes.
Sudipto Roy
semanticscholar +5 more sources
Live cell imaging of dynamic behaviors of motile cilia and primary cilium
Microscopy, 2018 The cilium is a tiny organelle, with a length of 1-10 μm and a diameter of ~200 nm, that projects from the surface of many cells and functions to generate fluid flow and/or sense extracellular signals from the environment. Abnormalities in cilia may cause a broad spectrum of disease, i.e. the so-called ciliopathies.
Faryal Ijaz, Koji Ikegami
semanticscholar +4 more sources
IFT74 variants cause skeletal ciliopathy and motile cilia defects in mice and humans.
PLoS Genetics, 2023 Motile and non-motile cilia play critical roles in mammalian development and health. These organelles are composed of a 1000 or more unique proteins, but their assembly depends entirely on proteins synthesized in the cell body and transported into the ...
Zeineb Bakey +25 more
doaj +3 more sources
Bioengineering, 2022 Motile cilia are hair-like microscopic structures which generate directional flow to provide fluid transport in various biological processes. Ciliary beating is one of the sources of cerebrospinal flow (CSF) in brain ventricles.
Huseyin Enes Salman +2 more
doaj +2 more sources
Mathematical Biosciences and Engineering, 2021 Primary cilia are non-motile, solitary (one per cell) microtubule-based organelles that emerge from the mother centriole after cells have exited the mitotic cycle.
Zhangli Peng +2 more
doaj +2 more sources
Signaling through the Primary Cilium
Frontiers in Cell and Developmental Biology, 2018 The presence of single, non-motile “primary” cilia on the surface of epithelial cells has been well described since the 1960s. However, for decades these organelles were believed to be vestigial, with no remaining function, having lost their motility. It
Gabrielle Wheway +2 more
doaj +2 more sources