Results 51 to 60 of about 11,920 (200)

Microfluidic pumping using artificial magnetic cilia

open access: yes, 2018
One of the vital functions of naturally occurring cilia is fluid transport. Biological cilia use spatially asymmetric strokes to generate a net fluid flow that can be utilized for feeding, swimming, and other functions.
Alexeev, Alexander   +2 more
core   +1 more source

Ciliary Proteins: Filling the Gaps. Recent Advances in Deciphering the Protein Composition of Motile Ciliary Complexes

open access: yesCells, 2019
Cilia are highly evolutionarily conserved, microtubule-based cell protrusions present in eukaryotic organisms from protists to humans, with the exception of fungi and higher plants.
Anna Osinka   +5 more
doaj   +1 more source

Exploring the role of fallopian ciliated cells in the pathogenesis of high-grade serous ovarian cancer [PDF]

open access: yes, 2018
High-grade serous epithelial ovarian cancer (HGSOC) is the fifth leading cause of cancer death in women and the first among gynecological malignancies. Despite an initial response to standard chemotherapy, most HGSOC patients relapse.
Baldassarre G   +9 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Integrative Transcriptomics and Proteomics Analyses to Reveal the Developmental Regulation of Metorchis orientalis: A Neglected Trematode With Potential Carcinogenic Implications

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Metorchis orientalis is a neglected zoonotic parasite of the gallbladder and bile duct of poultry, mammals, and humans. It has been widely reported in Asian, including China, Japanese, and Korea, where it is a potential threat to public health.
Jun-Feng Gao   +7 more
doaj   +1 more source

Evolutionary origins of sensation in metazoans: functional evidence for a new sensory organ in sponges [PDF]

open access: yes, 2014
Background: One of the hallmarks of multicellular organisms is the ability of their cells to trigger responses to the environment in a coordinated manner.
Farrar, Nathan   +4 more
core   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett   +8 more
wiley   +1 more source

The Primary Cilium as a Biomarker in the Hypoxic Adaptation of Bone Marrow-Derived Mesenchymal Stromal Cells: A Role for the Secreted Frizzled-Related Proteins

open access: yesBiomarker Insights, 2011
A pivotal role in guiding mesenchymal stem cell (MSC) differentiation has recently been attributed to the primary cilium. This solitary, non-motile microtubule-based organelle emerging from the cell surface acts as a sensorial membrane structure ...
Sébastien Proulx-Bonneau   +1 more
doaj   +1 more source

Realizing the physics of motile cilia synchronization with driven colloids

open access: yes, 2015
Cilia and flagella in biological systems often show large scale cooperative behaviors such as the synchronization of their beats in "metachronal waves".
Bruot, Nicolas, Cicuta, Pietro
core   +1 more source

Cilia at the node of mouse embryos sense fluid flow for left-right determination via Pkd2 [PDF]

open access: yes, 2012
Unidirectional fluid flow plays an essential role in the breaking of left-right (L-R) symmetry in mouse embryos, but it has remained unclear how the flow is sensed by the embryo.
A. Kawasumi   +33 more
core   +1 more source

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